Palmitoyl-CoA is an acyl-CoA thioester. It is an "activated" form of palmitic acid and can be transported into the mitochondrial matrix by the carnitine...
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Palmitoyl-CoA hydrolase (EC 3.1.2.2) is an enzyme in the family of hydrolases that specifically acts on thioester bonds. It catalyzes the hydrolysis of...
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Serine C-palmitoyltransferase (redirect from Palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating))
enzyme that catalyzes the chemical reaction: palmitoyl-CoA + L-serine ⇌ {\displaystyle \rightleftharpoons } CoA + 3-dehydro-D-sphinganine + CO2 Thus, the...
18 KB (1,755 words) - 20:13, 16 October 2024
acids (MUFAs), specifically oleate and palmitoleate from stearoyl-CoA and palmitoyl-CoA. Oleate and palmitoleate are major components of membrane phospholipids...
27 KB (3,137 words) - 21:10, 29 June 2024
Carnitine palmitoyltransferase I (redirect from Carnitine-palmitoyl transferase I)
known as carnitine acyltransferase I, CPTI, CAT1, CoA:carnitine acyl transferase (CCAT), or palmitoylCoA transferase I, is a mitochondrial enzyme responsible...
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Carnitine palmitoyltransferase II deficiency (redirect from Carnitine palmitoyl transferase 2 deficiency)
mechanism in which the enzyme must bind CoA before palmitoylcarnitine, and then the resulting product palmitoyl-CoA is the last substrate to be released...
26 KB (3,163 words) - 15:55, 16 October 2024
palmitoylcarnitine into palmitoyl-CoA. A related transferase is carnitine acyltransferase. Palmitoylcarnitine Palmitoyl CoA There are four different...
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involved in diverse cellular processes. Sphingosine is synthesized from palmitoyl CoA and serine in a condensation required to yield dihydrosphingosine. Dehydrosphingosine...
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Palmitoyl protein hydrolase/thioesterases is an enzyme (EC 3.1.2.22) that removes thioester-linked fatty acyl groups such as palmitate from modified cysteine...
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short chain fatty acyl-CoAs are negative feedback inhibitors of ACC. One such negative allosteric modulator is palmitoyl-CoA. Phosphorylation can result...
27 KB (2,990 words) - 21:27, 4 July 2024
receptor. Bombykol is known to be derived from acetyl-CoA via the C-16 fatty acyl palmitoyl-CoA. Palmitoyl-CoA is converted to bombykol in steps that involve...
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reaction palmitoyl-CoA + ecdysone ⇌ {\displaystyle \rightleftharpoons } CoA + ecdysone palmitate Thus, the two substrates of this enzyme are palmitoyl-CoA and...
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Palmitoyl-CoA. Palmitoyl-CoA has the ability to freely pass the outer mitochondrial membrane, but the inner membrane is impermeable to the Acyl-CoA and...
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mechanism consumes an acetyl coenzyme A (acetyl-CoA) and seven malonyl-CoA molecules to produce a palmitoyl-CoA. Synthesis of fatty acids is generally performed...
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this mechanism two products are released, AMP and acyl coa product. (Step 4, Figure 2) Acyl CoA is formed from long chain fatty acids through an acyl substitution...
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converted into acetyl-CoA. The overall net reaction, using palmitoyl-CoA (16:0) as a model substrate is: 7 FAD + 7 NAD+ + 7 CoASH + 7 H2O + H(CH2CH2)7CH2CO-SCoA...
23 KB (2,461 words) - 05:56, 15 October 2024
occurs as feedback inhibition by palmitoyl-CoA and activation by citrate. When there are high levels of palmitoyl-CoA, the final product of saturated fatty...
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(myelin-proteolipid) O-palmitoyltransferase (redirect from Palmitoyl-CoA:(myelin-proteolipid) O-palmitoyltransferase)
catalyzes the chemical reaction palmitoyl-CoA + [myelin proteolipid] ⇌ {\displaystyle \rightleftharpoons } CoA + O-palmitoyl-[myelin proteolipid] Thus, the...
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inhibitors: Guanosine triphosphate (GTP) Adenosine triphosphate (ATP) Palmitoyl-CoA Zn2+ Activators: Adenosine diphosphate (ADP) Leucine l-isoleucine l-valine...
15 KB (1,654 words) - 16:29, 28 July 2024
In terms of its biosynthesis, stearic acid is produced from palmitoyl-CoA, with malonyl-CoA a two-carbon building block (after decarboxylation). Stearic...
17 KB (1,568 words) - 08:03, 31 May 2024
Glycoprotein N-palmitoyltransferase (redirect from Palmitoyl-CoA:glycoprotein N-palmitoyltransferase)
enzyme that catalyzes the chemical reaction palmitoyl-CoA + glycoprotein ⇌ {\displaystyle \rightleftharpoons } CoA + N-palmitoylglycoprotein Thus, the two...
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Long-chain acyl-CoA dehydrogenase (EC 1.3.8.8, palmitoyl-CoA dehydrogenase, palmitoyl-coenzyme A dehydrogenase, long-chain acyl-coenzyme A dehydrogenase...
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palmitoyltransferase. The preferred substrates for this reaction are palmitoyl-CoA and serine. However, studies have demonstrated that serine palmitoyltransferase...
25 KB (2,774 words) - 16:47, 24 September 2024
of sphingomyelin synthesis involves the condensation of L-serine and palmitoyl-CoA. This reaction is catalyzed by serine palmitoyltransferase. The product...
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for palmitoyl-CoA ligase (FACL1)". Cytogenetics and Cell Genetics. 59 (1): 17–9. doi:10.1159/000133189. PMID 1531127. "Entrez Gene: ACSL1 acyl-CoA synthetase...
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reaction palmitoyl-CoA + dolichol ⇌ {\displaystyle \rightleftharpoons } CoA + dolichyl palmitate Thus, the two substrates of this enzyme are palmitoyl-CoA and...
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ACOT1 (redirect from Acyl-CoA thioesterase 1)
acyl-CoA hydrolases, acyl-CoA thioester hydrolases, and palmitoyl-CoA hydrolases. The reaction carried out by these enzymes is as follows: CoA ester...
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Glycoprotein O-fatty-acyltransferase (redirect from Fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase)
that catalyzes the chemical reaction palmitoyl-CoA + mucus glycoprotein ⇌ {\displaystyle \rightleftharpoons } CoA + O-palmitoylglycoprotein Thus, the two...
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3-oxoacyl-CoA + NADPH + H+ This microsomal complex extends palmitoyl-CoA and stearoyl-CoA (and their modified forms) to very-long-chain acyl CoAs. Beaudoin...
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Delta11-fatty-acid desaturase (redirect from Delta11-palmitoyl-CoA desaturase)
acid desaturase, Z/E11-desaturase, Delta11-palmitoyl-CoA desaturase) is an enzyme with systematic name acyl-CoA,hydrogen donor:oxygen Delta11-oxidoreductase...
2 KB (236 words) - 13:46, 26 August 2023