field of molecular biology, the peroxisome proliferator–activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription...
18 KB (1,897 words) - 23:57, 4 October 2024
Peroxisome proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear...
19 KB (2,091 words) - 05:22, 13 July 2024
Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that...
18 KB (1,964 words) - 09:49, 12 October 2024
Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor...
22 KB (2,567 words) - 20:42, 4 October 2024
PPAR agonist (redirect from Peroxisome proliferator-activated receptor agonist)
PPAR agonists are drugs which act upon the peroxisome proliferator-activated receptor. They are used for the treatment of symptoms of the metabolic syndrome...
9 KB (1,045 words) - 13:21, 2 November 2024
proposed to be the peroxisome proliferator-activated receptor alpha (PPAR-α). PEA also has affinity to cannabinoid-like G-coupled receptors GPR55 and GPR119...
47 KB (5,039 words) - 04:14, 20 September 2024
and Woronin bodies of filamentous fungi. Peroxisome proliferator-activated receptor "Definition of PEROXISOME". www.merriam-webster.com. Retrieved 2019-10-30...
33 KB (3,863 words) - 06:13, 27 July 2024
Telmisartan (category Angiotensin II receptor antagonists)
"Telmisartan prevents weight gain and obesity through activation of peroxisome proliferator-activated receptor-delta-dependent pathways". Hypertension. 55 (4):...
14 KB (1,192 words) - 05:32, 13 September 2024
very-low-density lipoprotein (VLDL). Acadesine GFT505 GW0742 Irisin Peroxisome proliferator-activated receptor Sodelglitazar SR9009 Koh B (2013-03-22). "Anti-doping...
20 KB (1,953 words) - 11:14, 12 November 2024
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is...
32 KB (3,863 words) - 10:06, 3 November 2024
increased risk of rhabdomyolysis. Fibrates stimulate peroxisome proliferator activated receptor (PPAR) alpha, which controls the expression of gene products...
10 KB (1,091 words) - 01:14, 8 October 2024
ester. It lowers lipid levels by activating peroxisome proliferator-activated receptor alpha (PPARα). PPARα activates lipoprotein lipase and reduces apoprotein...
26 KB (2,514 words) - 21:09, 28 September 2024
Another potential target of antiepileptic drugs is the peroxisome proliferator-activated receptor alpha. Some anticonvulsants have shown antiepileptogenic...
71 KB (5,797 words) - 20:15, 21 November 2024
particular receptors include buspirone, aripiprazole, buprenorphine, nalmefene and norclozapine. Examples of ligands activating peroxisome proliferator-activated...
4 KB (429 words) - 04:01, 14 February 2024
Thiazolidinediones or TZDs act by activating PPARs (peroxisome proliferator-activated receptors), a group of nuclear receptors, specific for PPARγ (PPAR-gamma...
20 KB (2,167 words) - 15:13, 20 September 2024
(January 2004). "Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear...
17 KB (1,945 words) - 06:08, 25 July 2024
a peroxisome proliferator-activated receptor (PPAR) agonist. It activates a type of receptor called the peroxisome proliferator-activated receptor alpha...
7 KB (548 words) - 05:04, 10 July 2024
by voluntary exercise. AMPK is required for increased peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) expression in skeletal muscle...
65 KB (7,149 words) - 14:04, 13 November 2024
Arachidonic acid (section PLA2 activation)
arachidonic acid. Receptors that activate this pathway include: A1 receptor D2 receptor α2 adrenergic receptor 5-HT1 receptor PLC may also be activated by MAP kinase...
21 KB (1,899 words) - 17:30, 2 October 2024
Pioglitazone selectively stimulates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ) and to a lesser extent PPAR-α. It...
28 KB (2,663 words) - 03:58, 30 September 2024
PFOA alters lipid metabolism. It is an agonist of PPARα and is a peroxisome proliferator in rodents contributing to a well understood form of oxidative...
127 KB (13,106 words) - 18:03, 6 November 2024
lipolysis. It does so by activating peroxisome proliferator-activated receptor alpha (PPARα) 'transcription factor ligand', a receptor that is involved in...
12 KB (950 words) - 06:13, 1 April 2024
"Obesity and breast cancer: the roles of peroxisome proliferator-activated receptor-γ and plasminogen activator inhibitor-1". PPAR Research. 2009: 345320...
13 KB (1,603 words) - 02:15, 10 March 2024
mainly realized through its activation of peroxisome proliferator-activated receptor gamma (PPARγ). PPARs are ligand-activated nuclear transcription factors...
33 KB (3,409 words) - 19:47, 26 August 2024
thiazolidinediones (pioglitazone and rosiglitazone), works by activating peroxisome proliferator-activated receptors (PPARs). Troglitazone is a ligand to both PPARα...
20 KB (2,044 words) - 13:18, 15 August 2024
triggering the activation of AMP-activated protein kinase (AMPK) which subsequently phosphorylates peroxisome proliferator-activated receptor gamma coactivator-1α...
82 KB (10,564 words) - 19:00, 9 November 2024
their 9-HODE counterparts) directly activate peroxisome proliferator-activated receptor gamma (PPARγ). This activation appears responsible for the ability...
67 KB (7,852 words) - 20:54, 18 October 2024
nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling". The...
14 KB (1,641 words) - 03:02, 20 June 2024
main active metabolite GFT1007 are peroxisome proliferator-activated receptor (PPAR) agonists, both of which activate PPAR-alpha, PPAR-gamma, and PPAR-delta...
14 KB (888 words) - 22:31, 11 November 2024
Genistein (category Glycine receptor antagonists)
of G protein-coupled estrogen receptor (affinity of 133 nM) activation of peroxisome proliferator-activated receptors (PPARs) inhibition of several tyrosine...
45 KB (4,451 words) - 09:21, 8 November 2024