field of molecular biology, the peroxisome proliferator–activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription...
17 KB (1,850 words) - 09:47, 3 May 2024
Peroxisome proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear...
19 KB (2,091 words) - 05:22, 13 July 2024
proliferator-activated receptor delta and peroxisome proliferator-activated receptor gamma, PPAR-alpha is part of the subfamily of peroxisome proliferator-activated receptors...
22 KB (2,563 words) - 18:52, 10 July 2024
Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that...
18 KB (1,963 words) - 04:51, 13 July 2024
PPAR agonist (redirect from Peroxisome proliferator-activated receptor agonist)
PPAR agonists are drugs which act upon the peroxisome proliferator-activated receptor. They are used for the treatment of symptoms of the metabolic syndrome...
9 KB (1,045 words) - 01:12, 27 April 2024
proposed to be the peroxisome proliferator-activated receptor alpha (PPAR-α). PEA also has affinity to cannabinoid-like G-coupled receptors GPR55 and GPR119...
51 KB (5,586 words) - 05:10, 1 March 2024
Telmisartan (category Angiotensin II receptor antagonists)
"Telmisartan prevents weight gain and obesity through activation of peroxisome proliferator-activated receptor-delta-dependent pathways". Hypertension. 55 (4):...
14 KB (1,179 words) - 06:17, 26 June 2024
very-low-density lipoprotein (VLDL). Acadesine GFT505 GW0742 Irisin Peroxisome proliferator-activated receptor Sodelglitazar SR9009 Koh B (2013-03-22). "Anti-doping...
20 KB (1,954 words) - 18:01, 12 July 2024
increased risk of rhabdomyolysis. Fibrates stimulate peroxisome proliferator activated receptor (PPAR) alpha, which controls the expression of gene products...
10 KB (1,091 words) - 19:14, 28 August 2023
Another potential target of antiepileptic drugs is the peroxisome proliferator-activated receptor alpha. Some anticonvulsants have shown antiepileptogenic...
70 KB (5,787 words) - 06:43, 29 June 2024
ester. It lowers lipid levels by activating peroxisome proliferator-activated receptor alpha (PPARα). PPARα activates lipoprotein lipase and reduces apoprotein...
26 KB (2,461 words) - 13:52, 11 July 2024
nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling". The...
14 KB (1,641 words) - 03:02, 20 June 2024
Kelly DP (October 2004). "Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control...
17 KB (1,995 words) - 21:24, 29 March 2024
lipolysis. It does so by activating peroxisome proliferator-activated receptor alpha (PPARα) 'transcription factor ligand', a receptor that is involved in...
12 KB (950 words) - 06:13, 1 April 2024
Pioglitazone selectively stimulates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ) and to a lesser extent PPAR-α. It...
28 KB (2,646 words) - 18:27, 11 July 2024
Thiazolidinediones or TZDs act by activating PPARs (peroxisome proliferator-activated receptors), a group of nuclear receptors, specific for PPARγ (PPAR-gamma...
20 KB (2,133 words) - 22:39, 27 April 2024
a dual PPAR agonist at the subtypes α (alpha) and γ (gamma) of the peroxisome proliferator-activated receptor (PPAR). Agonist action on PPARα lowers high...
9 KB (746 words) - 07:01, 29 May 2024
active metabolite GFT1007 are peroxisome proliferator-activated receptor (PPAR) agonists, both of which activate PPAR-alpha, PPAR-gamma, and PPAR-delta...
12 KB (674 words) - 10:19, 1 July 2024
Farnesoid X receptor has been shown to interact with: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha and Retinoid X receptor alpha. A number...
17 KB (1,945 words) - 06:12, 13 July 2024
Arachidonic acid (section PLA2 activation)
arachidonic acid. Receptors that activate this pathway include: A1 receptor D2 receptor α-2 adrenergic receptor 5-HT1 receptor PLC may also be activated by MAP kinase...
21 KB (1,878 words) - 21:32, 2 June 2024
deacetylase 5, MAP3K7IP2, MECP2, Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor gamma Promyelocytic leukemia...
23 KB (2,678 words) - 09:26, 16 May 2024
Carnitine (section Activation)
ultimately replenishing the supply of ATP. Peroxisome proliferator-activated receptor alpha (PPARα) is a nuclear receptor that functions as a transcription factor...
30 KB (3,278 words) - 20:35, 26 April 2024
Oleoylethanolamide (OEA) is an endogenous peroxisome proliferator-activated receptor alpha (PPAR-α) agonist. It is a naturally occurring ethanolamide lipid...
7 KB (654 words) - 01:49, 3 December 2023
NFKB1, PCAF, PPARGC1A, Peroxisome proliferator-activated receptor alpha, SNW1, STAT3, STAT6, TRIP4, and Thyroid hormone receptor beta. GRCh38: Ensembl...
15 KB (1,725 words) - 17:17, 1 July 2024
interact with the aryl hydrocarbon receptor, peroxisome proliferator-activated receptor alpha and the aryl hydrocarbon receptor nuclear translocator. Further...
12 KB (1,468 words) - 05:27, 9 February 2024
Roberts-Thomson SJ (July 2004). "Effect of the peroxisome proliferator-activated receptor beta activator GW0742 in rat cultured cerebellar granule neurons"...
9 KB (827 words) - 19:19, 6 May 2024
Pirinixic acid is a peroxisome proliferator-activated receptor alpha (PPARα) agonist that is under experimental investigation for prevention of severe...
7 KB (675 words) - 03:19, 6 April 2023
Pemafibrate, sold under the brand namd Parmodia, is a peroxisome proliferator-activated receptor alpha (PPARα) agonist. It is developed and marketed by Kowa...
4 KB (91 words) - 11:40, 3 January 2024
Schwammenthal E, Adler Y, Goldenberg I, et al. (May 2004). "Peroxisome proliferator-activated receptor ligand bezafibrate for prevention of type 2 diabetes mellitus...
8 KB (688 words) - 09:07, 23 September 2023
"Molecular mechanisms of alcoholic fatty liver: role of peroxisome proliferator-activated receptor alpha". Alcohol. 34 (1): 35–8. doi:10.1016/j.alcohol.2004...
38 KB (3,896 words) - 13:25, 18 May 2024