Physiologically based pharmacokinetic (PBPK) modeling is a mathematical modeling technique for predicting the absorption, distribution, metabolism and...
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Bioequivalence Generic drugs Physiologically based pharmacokinetic modelling Plateau principle Toxicokinetics Pharmacokinetics. (2006). In Mosby's Dictionary...
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Fluorodeoxyglucose Multi-compartment model Patlak plot Pharmacokinetics Physiologically-based pharmacokinetic modelling G. Lucignani; G. Paganelli; E. Bombardieri...
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Pharmacometrics (category Pharmacokinetics)
Physiologically-Based Pharmacokinetic models integrate physiological information to simulate drug behavior in various tissues and organs. These models consider organ-specific...
10 KB (1,306 words) - 19:51, 27 March 2024
Spendiff, M. K.; Cocker, J.; Loizou, G. D. (2006). "Physiologically based pharmacokinetic modelling of human exposure to 2-butoxyethanol". Toxicol. Lett...
24 KB (2,388 words) - 14:53, 3 August 2024
Nephrotoxicity Neurotoxicity Ototoxicity Paracelsus Physiologically-based pharmacokinetic modelling. Poison Reference dose Registry of Toxic Effects of...
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45: 55–65. Franks S.J., Spendiff M.K., et al., 2006, Physiologically based pharmacokinetic modelling of human exposure to 2-butoxyethanol, Toxicology Letters...
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engineering Biological neuron models Compartmental models in epidemiology Physiologically-based pharmacokinetic modelling Cobelli, Claudio; Foster, David...
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Neuroinformatics Mathematical model Compartmental models in epidemiology Physiologically-based pharmacokinetic modelling Ermentrout, Bard; Terman H. David...
22 KB (3,115 words) - 21:20, 25 October 2023
His research in pharmacology, has been particularly in physiologically based pharmacokinetics (that deals with the movement in time of drugs and their...
13 KB (1,188 words) - 14:32, 4 August 2024
Biological half-life (category Pharmacokinetics)
and each part with a different biological half-life (physiologically-based pharmacokinetic modelling). Attempts to remove a substance from the whole organism...
23 KB (2,515 words) - 08:39, 9 October 2024
Glycyrrhizin (section Pharmacokinetics)
DeJongh J (May 2001). "The pharmacokinetics of glycyrrhizic acid evaluated by physiologically based pharmacokinetic modeling". Drug Metabolism Reviews...
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Leon Aarons (section Data modelling)
collaborated on earlier research published in 2008 used physiologically based pharmacokinetic modelling (PBPK) to "evaluate the potential CYP3A4 inhibitory...
15 KB (1,599 words) - 08:27, 4 May 2024
Daridorexant (section Pharmacokinetics)
strong CYP3A4 inhibitor itraconazole, on the basis of physiologically-based pharmacokinetic modeling, would be expected to increase daridorexant exposure...
47 KB (4,020 words) - 00:39, 3 November 2024
2,4-Dinitrophenol (section Pharmacokinetics)
Dhaval K. (1 June 2022). "Physiologically-based pharmacokinetic model for 2,4-dinitrophenol". Journal of Pharmacokinetics and Pharmacodynamics. 49 (3):...
35 KB (3,728 words) - 03:55, 31 October 2024
Drug discovery (redirect from Target base drug discovery)
metabolism Fragment-based drug discovery High content screening Pharmacogenetics Pharmacognosy Physiologically-based pharmacokinetic modelling Pre-clinical development...
58 KB (6,735 words) - 03:23, 19 October 2024
process parameters can then be integrated into so called "physiologically based pharmacokinetic models" or PBPK. In vitro studies permit a species-specific...
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PMID 24857840. Guo J, Zhou D, Li Y, Khanh BH (November 2015). "Physiologically based pharmacokinetic modeling to predict complex drug-drug interactions: a case study...
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health record — Personalized medicine — Pharmacology — Physiologically based pharmacokinetic modelling — Point of care testing — Positron emission tomography...
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Valganciclovir (section Pharmacokinetics)
M, Greig G, Reigner B, Parrott N (November 2016). "A Physiologically Based Pharmacokinetic Model for Ganciclovir and Its Prodrug Valganciclovir in Adults...
17 KB (1,265 words) - 19:42, 20 December 2023
of his Ph.D. thesis, on the use of physiologically based pharmacokinetic models and stochastic carcinogenesis models for risk assessment, was developed...
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ethylene glycol ethyl ether acetate and validation of a physiologically based pharmacokinetic model for rat and human". Toxicology and Applied Pharmacology...
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tablets in specific populations clinical trials based on mechanistic physiologically-based pharmacokinetic model". European Journal of Pharmaceutical Sciences...
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M.; Killam, A. L.; Dittrich, H. C. (January 1999). "Physiologically based pharmacokinetic model for fluorocarbon elimination after the administration...
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S, Shipp AM, Yager JW, Clewell HJ (January 2004). "Physiologically based pharmacokinetic modeling of arsenic in the mouse". Journal of Toxicology and...
80 KB (9,472 words) - 03:57, 2 November 2024
the genetic control of alcohol dehydrogenase into a physiologically based pharmacokinetic model for ethanol in humans". Toxicological Sciences. 78 (1):...
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Pharmacology (section Pharmacokinetics)
drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically...
48 KB (4,744 words) - 21:42, 24 September 2024
Cheminformatics Biomedical informatics Orphan drug Physiologically-based pharmacokinetic modelling Pharmaceuticals in India Generic drug New chemical...
90 KB (12,115 words) - 03:24, 15 July 2024
1515/jip-2012-0081. Collins Licata, A.; et al. (2001). "A Physiologically Based Pharmacokinetic Model for Methyl tert-Butyl Ether in Humans: Implementing Sensitivity...
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active metabolite. El-Masri HA, Portier CJ (June 1998). "Physiologically based pharmacokinetics model of primidone and its metabolites phenobarbital and...
2 KB (62 words) - 01:52, 25 February 2021