• Thumbnail for Promyelocytic leukemia protein
    Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene. PML protein is a tumor suppressor...
    33 KB (4,053 words) - 07:02, 10 July 2024
  • Thumbnail for Acute promyelocytic leukemia
    Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. In APL, there is an abnormal...
    31 KB (3,263 words) - 14:35, 27 December 2024
  • Thumbnail for Acute myeloid leukemia
    forms of acute myeloid leukemia with recurrent genetic abnormalities: t(8;21), inv(16) or t(16;16), and acute promyelocytic leukemia with PML-RARA, in which...
    75 KB (7,543 words) - 18:38, 10 December 2024
  • Thumbnail for Nuclear bodies
    (also called splicing speckles), histone locus bodies, and promyelocytic leukemia protein (PML) nuclear bodies (also called PML oncogenic dots). Nuclear...
    17 KB (1,890 words) - 16:27, 9 October 2024
  • Thumbnail for Tretinoin
    acne and acute promyelocytic leukemia. For acne, it is applied to the skin as a cream, gel or ointment. For acute promyelocytic leukemia, it is effective...
    31 KB (2,915 words) - 14:46, 21 January 2025
  • Thumbnail for Zinc finger and BTB domain-containing protein 16
    Heparin-binding EGF-like growth factor, Nuclear receptor co-repressor 2, Promyelocytic leukemia protein RUNX1T1, Retinoic acid receptor alpha, SIN3A, SIN3B, and ZBTB32...
    23 KB (2,635 words) - 16:29, 26 November 2023
  • Thumbnail for Cell nucleus
    which promotes transcription of small nuclear RNA (snRNA). Promyelocytic leukemia protein (PML-nuclear bodies) are spherical bodies found scattered throughout...
    88 KB (10,001 words) - 18:00, 4 December 2024
  • leukoencephalopathy, rare and usually fatal disorder Promyelocytic leukemia protein, tumor suppressor protein Programmable Macro Language, for Aveva industrial...
    844 bytes (118 words) - 02:21, 28 May 2024
  • Thumbnail for Retinoblastoma protein
    inhibitor-2 Polymerase (DNA directed), alpha 1 PRDM2 PRKRA Prohibitin Promyelocytic leukemia protein RBBP4 RBBP7 RBBP8 RBBP9 SNAPC1 SKP2 SNAPC3 SNW1 SUV39H1 TAF1...
    79 KB (9,502 words) - 07:42, 4 September 2024
  • Thumbnail for Papillomaviridae
    "Establishment of papillomavirus infection is enhanced by promyelocytic leukemia protein (PML) expression". Proceedings of the National Academy of Sciences...
    63 KB (7,242 words) - 05:09, 15 April 2024
  • Thumbnail for HHEX
    HHEX (redirect from HHEX (protein))
    RA, Borden KL (Nov 1999). "The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis...
    12 KB (1,534 words) - 08:17, 2 November 2024
  • Thumbnail for Death-associated protein 6
    relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in the...
    11 KB (1,528 words) - 20:53, 21 December 2023
  • Thumbnail for SKI protein
    homolog 2, Mothers against decapentaplegic homolog 3, NFIX, Promyelocytic leukemia protein, SKIL, and SNW1. GRCh38: Ensembl release 89: ENSG00000157933...
    20 KB (2,418 words) - 01:54, 22 December 2023
  • Thumbnail for Dentatorubral–pallidoluysian atrophy
    alter the distribution of the intranuclear structures, such as promyelocytic leukemia protein (PML) nuclear bodies. Although the role of PML bodies is unclear...
    23 KB (2,513 words) - 22:07, 9 September 2024
  • as Compound Huangdai (复方黄黛), is a medication used to treat acute promyelocytic leukemia. Effectiveness appears similar to arsenic trioxide. It is generally...
    10 KB (954 words) - 14:26, 17 January 2025
  • Thumbnail for HHV Infected Cell Polypeptide 0
    HHV Infected Cell Polypeptide 0 (category Proteins)
    dots or promyelocytic leukemia (PML) nuclear bodies, and alters the expression of host and viral genes in combination with a neuron specific protein. At later...
    24 KB (2,680 words) - 02:32, 15 January 2025
  • of numerical mathematics Cyto-Plasmic Promyelocytic Leukaemia (cPML), a form of the promyelocytic leukemia protein Central Pennsylvania Multiple Listing...
    644 bytes (102 words) - 20:13, 26 July 2022
  • Thumbnail for Thymine-DNA glycosylase
    CREB-binding protein, Estrogen receptor alpha, Promyelocytic leukemia protein, SUMO3, and Small ubiquitin-related modifier 1. Click on genes, proteins and metabolites...
    12 KB (1,613 words) - 21:58, 28 July 2024
  • Thumbnail for CHEK2
    transcription factor E2F1 and the promyelocytic leukemia protein (PML) involved in apoptosis (programmed cell death). The CHK2 protein plays a critical role in...
    28 KB (2,797 words) - 09:37, 2 October 2024
  • Thumbnail for TNFAIP3
    2001.0921. PMID 11594795. Wu WS, Xu ZX, Chang KS (2002). "The promyelocytic leukemia protein represses A20-mediated transcription". J. Biol. Chem. 277 (35):...
    15 KB (1,971 words) - 12:07, 15 November 2024
  • Thumbnail for Glucocorticoid receptor
    PMID 10903152. Lin DY, Lai MZ, Ann DK, Shih HM (May 2003). "Promyelocytic leukemia protein (PML) functions as a glucocorticoid receptor co-activator by...
    37 KB (4,035 words) - 09:01, 19 August 2024
  • Thumbnail for Chromosome 15
    PLA2G4D: encoding protein Phospholipase A2 group IVD PLA2G4E: encoding protein Phospholipase A2 group IVE PML: promyelocytic leukemia protein (involved in...
    34 KB (3,031 words) - 03:36, 10 March 2024
  • Thumbnail for Nuclear receptor 4A1
    with: AKT1, Bcl-2, HIF1A, Nuclear receptor co-repressor 2, Promyelocytic leukemia protein, Retinoid X receptor alpha, and Von Hippel-Lindau tumor suppressor...
    21 KB (2,532 words) - 05:38, 11 November 2024
  • Thumbnail for GATA2
    "Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor...
    34 KB (4,038 words) - 10:22, 27 November 2024
  • Thumbnail for Fanconi anemia
    blood. All of the subtypes of AML can occur in FA with the exception of promyelocytic. However, myelomonocytic and acute monocytic are the most common subtypes...
    37 KB (4,140 words) - 20:00, 18 November 2024
  • Thumbnail for Arsenic trioxide
    of adults with newly-diagnosed low-risk acute promyelocytic leukemia whose acute promyelocytic leukemia is characterized by the presence of the t(15;17)...
    25 KB (2,193 words) - 16:38, 12 January 2025
  • involved in fatty acid transport and β-oxidation through a promyelocytic leukemia protein (PML)/peroxisome proliferation-activated receptor-gamma coactivator...
    31 KB (3,375 words) - 16:48, 13 January 2025
  • Thumbnail for Zinc finger protein 226
    promyelocytic leukemia, a condition resulting in the abundance of blood forming cells in the bone marrow, promyelocytic leukemia zinc finger proteins...
    36 KB (3,870 words) - 02:04, 11 June 2024
  • Thumbnail for 60S ribosomal protein L11
    been shown to interact with: BLMH, Mdm2, NOP53, P16, P53, and Promyelocytic leukemia protein GRCh38: Ensembl release 89: ENSG00000142676 – Ensembl, May 2017...
    10 KB (1,160 words) - 21:50, 21 April 2024
  • XRCC1 BRCT in collaboration with Tomas Lindahl's group, PML (promyelocytic leukemia protein) structure function studies and the characterisation of the...
    10 KB (1,059 words) - 01:18, 26 December 2024