Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
35 KB (3,831 words) - 18:08, 20 August 2024
In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...
27 KB (2,665 words) - 17:03, 6 April 2024
A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
14 KB (1,210 words) - 13:35, 14 June 2024
5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
65 KB (7,149 words) - 14:24, 16 January 2025
biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that...
11 KB (1,182 words) - 22:08, 3 April 2025
MTOR (redirect from Serine/threonine protein kinase mTOR)
phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR links with other proteins and serves as a core component of two distinct protein complexes...
120 KB (12,682 words) - 14:38, 16 January 2025
Rho-associated protein kinase or Rho-associated coiled-coil kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine specific...
19 KB (2,181 words) - 21:49, 18 March 2025
The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
14 KB (1,447 words) - 09:31, 22 December 2023
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
46 KB (5,510 words) - 21:54, 29 November 2024
Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK)...
3 KB (296 words) - 17:06, 14 September 2023
Myotonin-protein kinase (MT-PK) also known as myotonic dystrophy protein kinase (MDPK) or dystrophia myotonica protein kinase (DMPK) is an enzyme that...
19 KB (2,426 words) - 16:47, 30 March 2024
Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently...
11 KB (1,347 words) - 16:18, 9 February 2025
p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines...
14 KB (1,385 words) - 10:32, 28 April 2024
response to extracellular signals. Key proteins involved are PI3K (phosphatidylinositol 3-kinase) and Akt (protein kinase B). Initial stimulation by one of the...
36 KB (4,072 words) - 15:49, 12 April 2025
In the field of biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in...
18 KB (2,127 words) - 19:11, 8 April 2024
cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number...
8 KB (825 words) - 21:37, 20 April 2023
switch in many cellular functions. Tyrosine kinases belong to a larger class of enzymes known as protein kinases which also attach phosphates to other amino...
44 KB (5,283 words) - 12:50, 27 December 2024
BRAF (gene) (redirect from B-raf 1)
the protein is more formally known as serine/threonine-protein kinase B-Raf. The B-Raf protein is involved in sending signals inside cells which are involved...
50 KB (5,393 words) - 08:57, 15 March 2025
Protein kinase RNA-activated also known as protein kinase R (PKR), interferon-induced, double-stranded RNA-activated protein kinase, or eukaryotic translation...
39 KB (4,414 words) - 07:13, 30 December 2024
Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor,...
39 KB (4,393 words) - 05:21, 26 March 2025
Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma)...
21 KB (2,648 words) - 12:12, 26 July 2024
transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines, ultraviolet...
14 KB (1,626 words) - 20:50, 30 May 2024
In cell biology, protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling...
29 KB (2,856 words) - 15:13, 2 December 2024
Protein kinase C, zeta (PKCζ), also known as PRKCZ, is a protein in humans that is encoded by the PRKCZ gene. The PRKCZ gene encodes at least two alternative...
22 KB (2,666 words) - 17:28, 4 November 2024
by a protein kinase by the addition of a covalently bound phosphate group. Phosphorylation alters the structural conformation of a protein, causing it...
67 KB (7,955 words) - 04:17, 8 April 2025
unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not...
28 KB (3,078 words) - 17:48, 25 January 2025
A protein kinase inhibitor (PKI) is a type of enzyme inhibitor that blocks the action of one or more protein kinases. Protein kinases are enzymes that...
25 KB (887 words) - 03:14, 22 March 2025
G protein-coupled receptor kinases (GPCRKs, GRKs) are a family of protein kinases within the AGC (protein kinase A, protein kinase G, protein kinase C)...
18 KB (2,053 words) - 11:50, 28 December 2024
AKT1 (category Protein kinases)
serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that...
24 KB (2,818 words) - 09:21, 25 January 2025
Ribosomal protein S6 kinase beta-1 (S6K1), also known as p70S6 kinase (p70S6K, p70-S6K), is an enzyme (specifically, a protein kinase) that in humans...
18 KB (2,099 words) - 07:40, 21 March 2025