The Friedel–Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877 to attach substituents to an aromatic ring....

alkylation and acylation reactions with Charles Friedel in 1876. James Crafts, the son of Royal Altamont Crafts and Marianne Mason (daughter of Senator Jeremiah...

and mineralogy at the Sorbonne. Friedel developed the Friedel-Crafts alkylation and acylation reactions with James Crafts in 1877, and attempted to make...

sulfonation, alkylation Friedel–Crafts reaction and acylation Friedel–Crafts reaction. The most widely practised example of this reaction is the ethylation...

Friedel-Crafts reaction Friedel family, a rich lineage of French scientists: Charles Friedel (1832–1899), French chemist known for the Friedel-Crafts...

attack arenes. Acylium ions are intermediates in several reactions, such as the Friedel-Crafts acylation of arenes by acetyl chloride in the presence of...

reactions involving carbon–carbon or carbon–heteroatom bond formation can be catalyzed by Lewis acids. Examples include the Friedel-Crafts reaction,...

for the German chemist Ludwig Gattermann and is similar to the Friedel–Crafts reaction. Modifications have shown that it is possible to use sodium cyanide...

in the Friedel-Crafts reaction. Here, a strong Lewis acid is required to generate either a carbocation from an alkyl halide in the Friedel-Crafts alkylation...

home in the "Zone of Interest" next to the concentration camp. Christian Friedel stars as Rudolf Höss alongside Sandra Hüller as Hedwig Höss. Development...

3-Benzoylpropanoic acid itself can be obtained by a Haworth reaction (a variant of the Friedel-Crafts reaction) from benzene and succinic anhydride. The intramolecular...

extensive biodegradable yield over BAB-based sulfonates in the 1960s. Friedel-Crafts alkylation: alkylbenzenes can be synthesized from olefins or alkyl halides...

the Friedel–Crafts reaction Georges Friedel (1865–1933), here above described, French crystallographer and mineralogist; son of Charles Edmond Friedel (1895–1972)...

moderately and strongly deactivated substrates that are inert to Friedel-Crafts reactions like acetophenone, nitrobenzene and p-chloronitrobenzene do show...

1914 via the reaction of the methyl Grignard reagent on 2-furonitrile. Modern industrial synthesis generally involves the Friedel–Crafts acylation of...

Frankland–Duppa reaction Fráter–Seebach alkylation Free radical halogenation Freund reaction Friedel–Crafts acylation Friedel–Crafts alkylation Friedländer...

dibutyltin dilaurate) and polymer stabilizers. SnCl4 is used in Friedel–Crafts reactions as a Lewis acid catalyst. For example, the acetylation of thiophene...

chloride to give the corresponding acyl chloride in a process known as a Friedel-Crafts acylation. The resulting acyl chloride can be hydrolysed to form the...

not tennessine. Reaction sequence: organic reduction of ethyl benzoylacetate by sodium borohydride to a diol, followed by Friedel-Crafts alkylation with...

reactions. The compound undergoes reactions typical of other phenyl rings, including hydroxylation, nitration, halogenation, sulfonation, and Friedel–Crafts...

is highly susceptible to ring substitution by Friedel–Crafts reactions such as alkylation. This reaction is exploited en route to popular antioxidants...

controlled, this precursor can be prepared by a standard Friedel-Crafts acylation reaction by mixing chlorobenzene with propionyl chloride in the presence...

prohibitively expensive on a large scale. Examples include the Heck reaction, and Friedel–Crafts reactions. Because most bioactive compounds are chiral, many pharmaceuticals...

reagents. aryl ketones can be prepared in the Friedel–Crafts acylation, the related Houben–Hoesch reaction, and the Fries rearrangement. Ozonolysis, and...

ketone is prepared today as it was originally by Michler using the Friedel-Crafts acylation of dimethylaniline (C6H5NMe2) using phosgene (COCl2) or equivalent...

603 (2004); Vol. 79, p.93 (2002).Link Diastereoselective Friedel-Crafts Cyclization Reactions to 2-Substituted 1-Phenyl-1,2,3,4-tetrahydronaphthalenes...

acetylations. Acetylations are often used in making C-acetyl bonds in Friedel-Crafts reactions. Carbanions and their equivalents are susceptible to acetylations...

ligand is indicated by its ability to undergo Friedel-Crafts reactions, e.g. with acetyl chloride. Such reactions are slower on the tricarbonyl(mesitylene)molybdenum...

stoichiometry. For example, the methylation of benzene (C6H6), through a Friedel–Crafts reaction using AlCl3 as a catalyst, may produce singly methylated (C6H5CH3)...

technical science for his study of “Velocity measurements in the reaction of Friedel and Crafts” [translated from Dutch]. He subsequently worked as an assistant...