Raloxifene, sold under the brand name Evista among others, is a medication used to prevent and treat osteoporosis in postmenopausal women and those on...
46 KB (4,794 words) - 20:27, 17 February 2025
antiestrogenic activity. Raloxifene is a SERM that is more antiestrogenic than tamoxifen; both are estrogenic in bone, but raloxifene is antiestrogenic in...
58 KB (6,581 words) - 03:00, 21 February 2025
recommended for 10 years. In 2006, the large STAR clinical study concluded that raloxifene is also effective in reducing the incidence of breast cancer. Updated...
88 KB (9,262 words) - 00:51, 17 February 2025
Study of Tamoxifen and Raloxifene (STAR) is a clinical trial from the early 2000s designed determine how the drug raloxifene compares with the drug tamoxifen...
3 KB (222 words) - 21:00, 20 December 2023
Estradiol/raloxifene (E2/RLX) is a tissue-selective estrogen complex (TSEC) which was studied for potential use in menopausal hormone therapy but was never...
4 KB (219 words) - 13:09, 21 November 2024
infarction. In postmenopausal women, the selective estrogen receptor modulator raloxifene is occasionally administered instead of bisphosphonates. Bisphosphonates...
31 KB (3,516 words) - 17:44, 3 February 2025
Exscalate4Cov (section Raloxifene)
new treatments. During the European Exscalate4Cov project activities, raloxifene was selected through a combined approach of drug repurposing and in-silico...
28 KB (2,560 words) - 06:48, 6 January 2025
Antiestrogen withdrawal response (redirect from Raloxifene withdrawal syndrome)
with the selective estrogen receptor modulators (SERMs) tamoxifen and raloxifene. The phenomenon indicates that these agents can somehow result in stimulation...
3 KB (293 words) - 22:58, 13 December 2023
breast cancer lesions to tamoxifen and aromatase inhibitors. Another SERM, raloxifene, has been used as a preventive chemotherapy for women judged to have a...
38 KB (4,062 words) - 14:18, 6 November 2024
Intravenous (IV) iron sucrose Conjugated estrogens Teriparatide Naproxen Raloxifene Long-acting adrenergic beta-agonists (LABAs) Hydroxymethylglutaryl-coenzyme...
19 KB (2,010 words) - 08:43, 23 February 2025
not increase the risk of breast cancer. Jordan's paper The Effect of Raloxifene on Risk of Breast Cancer in Postmenopausal Women: Results from the More...
27 KB (3,013 words) - 23:59, 19 August 2024
throughout the body. The most commonly prescribed SERMs are raloxifene and tamoxifen. Raloxifene exhibits oestrogen agonist activity on bone and lipids, and...
90 KB (10,291 words) - 21:53, 14 February 2025
enlargement. Selective estrogen receptor modulators (SERMs) such as tamoxifen, raloxifene, and clomifene may be beneficial in the treatment of gynecomastia but...
63 KB (6,565 words) - 04:48, 12 February 2025
selective estrogen receptor modulators (SERMs) like tamoxifen, clomifene, and raloxifene, the ER silent antagonist and selective estrogen receptor degrader (SERD)...
8 KB (745 words) - 20:56, 24 November 2024
the carcinogen nitrosomethylurea and is significantly more potent than raloxifene in this regard. Arzoxifene is devoid of the uterotrophic effects of tamoxifen...
6 KB (513 words) - 15:16, 19 January 2025
conjugated estrogens), selective estrogen receptor modulators (e.g., raloxifene, bazedoxifene), and bisphosphonates (e.g., alendronic acid, risedronic...
18 KB (1,936 words) - 20:18, 16 February 2025
Services' Agency for Healthcare Research and Quality suggests that tamoxifen, raloxifene, and tibolone used to reduce the risk of breast cancer significantly reduce...
56 KB (5,314 words) - 06:11, 14 January 2025
two years in women 50 to 74 years of age. The medications tamoxifen or raloxifene may be used in an effort to prevent breast cancer in those who are at...
140 KB (15,850 words) - 04:24, 16 February 2025
associated with the same adverse effects as NSAIDs. Daily use of tamoxifen or raloxifene reduce the risk of breast cancer in high-risk women. The benefit versus...
185 KB (20,132 words) - 20:16, 16 February 2025
coagulation, in contrast to estrogens and other SERMs like tamoxifen and raloxifene. A binding assay was also performed to measure the affinity of ospemifene...
15 KB (1,615 words) - 23:22, 31 January 2025
found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP. It is also used in the manufacturing...
5 KB (352 words) - 00:48, 14 August 2023
anastrozole) and selective estrogen receptor modulators (e.g., tamoxifen, raloxifene) can interfere with and prevent the estrogenic effects of NPP. 5α-Reductase...
23 KB (2,127 words) - 06:16, 14 January 2025
antagonists/inverse agonists: Pitolisant SERM (selective estrogen receptor modulators) Raloxifene Vasodilators Minoxidil Antipsychotic medications: Droperidol Haloperidol...
17 KB (1,474 words) - 14:44, 17 December 2024
rafivirumab (INN) rafoxanide (INN) ralitoline (INN) ralitrexed (INN) raloxifene (INN) raltegravir (USAN) ramatroban (INN) ramciclane (INN) ramelteon (USAN)...
5 KB (287 words) - 01:31, 28 November 2024
some cases of gynecomastia but it is not as effective as tamoxifen or raloxifene for this indication. It has shown variable results for gynecomastia (probably...
48 KB (4,759 words) - 07:45, 28 January 2025
S2CID 20163452. Gauthier K, Bai A, Perras C, et al. (2012). "Denosumab, Raloxifene, and Zoledronic Acid for the Treatment of Postmenopausal Osteoporosis:...
99 KB (9,752 words) - 15:39, 31 January 2025
conducted drug repurposing experiments, leading to the identification of raloxifene as a possible candidate for treating early-stage COVID-19 patients. According...
18 KB (1,987 words) - 13:53, 26 October 2024
menopausal symptoms. It is not recommended for osteoporosis by itself. Raloxifene, while effective in decreasing vertebral fractures, does not affect the...
141 KB (15,951 words) - 05:24, 20 February 2025
significantly higher than reductions found with the related SERMs tamoxifen and raloxifene. In accordance, a network meta-analysis of SERMs for breast cancer prevention...
10 KB (810 words) - 15:44, 18 January 2025
testolactone are banned. Selective estrogen receptor modulators, including raloxifene, tamoxifen and toremifene are banned. Clomiphene, cyclofenil, fulvestrant...
20 KB (1,822 words) - 20:19, 13 December 2024