Signal transducing adaptor proteins (STAPs) are proteins that are accessory to main proteins in a signal transduction pathway. Adaptor proteins contain...

GPCR function. G proteins are important signal transducing molecules in cells. "Malfunction of GPCR [G Protein-Coupled Receptor] signaling pathways are involved...

Adaptor protein may refer to: Signal transducing adaptor protein Vesicular transport adaptor protein Clathrin adaptor protein, also known as adaptin This...

of the MAP/ERK signal transduction pathway are called RASopathies. Janus kinase Phosphatase Signal transducing adaptor protein G protein-coupled receptor...

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events. Proteins responsible...

cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa), also known as LCP2 or SLP-76, is a signal-transducing adaptor protein expressed...

The Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors...

Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with...

function of this protein. STAM1 contains multiple amino acid sites that are phosphorylated and ubiquitinated. Signal transducing adaptor molecule has been...

receptor binds to an adaptor protein (GRB2), which couples the signal to further downstream signaling processes. For example, one of the signal transduction pathways...

the cell to have signal transduction mechanisms to transduce first messenger into second messengers, so that the extracellular signal may be propagated...

drugs used for cancer therapy. Signal transducing adaptor protein, a helper protein used by major proteins in signalling pathways. Aaronson DS, Horvath...

metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal. This modulation...

In biology, scaffold proteins are crucial regulators of many key signalling pathways. Although scaffolds are not strictly defined in function, they are...

are three types of juxtracrine signaling: A membrane-bound ligand (protein, oligosaccharide, lipid) and a membrane protein of two adjacent cells interact...

'to bind'. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. The binding typically...

causes Ca2+ to dissociate from GTPase-activating protein (GAP), also known as regulator of G protein signaling. The liberated GAP deactivates transducin, terminating...

prepropeptides also contain a signal peptide, spacer peptides, and cleavage sites. The signal peptide sequence guides the protein to the secretory pathway...

structures, composed of protein, that receive and transduce signals that may be integrated into biological systems. These signals are typically chemical...

brain, spleen, and neonatal kidney. It is a G protein-coupled receptor (GPCR), coupled to the Gi protein, and its activation in the brain mediates hyperpolarization...

with a 3-oxo-HSL quorum-sensing signal, there is an up-regulation of flagellar assembly. Yet, flagellin, the main protein component of flagella, can act...

for cellular signalling, for once it enters the cytosol of the cytoplasm it exerts allosteric regulatory effects on many enzymes and proteins. Ca2+ can act...

domain of the receptor. An adaptor protein (such as SOS) recognizes the phosphorylated tyrosine on the receptor. This protein functions as a bridge which...

Cytokines are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Due to their size, cytokines cannot cross the lipid...

AIF-interacting proteins in the inner mitochondrial membrane and intermembrane space will help researchers identify the mechanism of the signalling pathway that...

Both have plasma membranes and ribosomes (structures that synthesize proteins[clarification needed] and float free in cytoplasm). Two unique characteristics...

sites Signal transducing adaptor protein, proteins that provide mechanisms by which receptors can amplify and regulate downstream effector proteins Linker...

substrate 2 is a protein that in humans is encoded by the FRS2 gene. FRS2 is an 80 kDa membrane-anchored signal transducing adaptor protein (STAP) that links...

from proteins to biogenic amines to protons, but all transduce this signal via a mechanism of G-protein coupling. This is made possible by a guanine-nucleotide...

Signal-transducing adaptor protein 2 is a protein that in humans is encoded by the STAP2 gene. This gene encodes the substrate of breast tumor kinase...