• Thumbnail for Syntaxin
    Syntaxins are a family of membrane integrated Q-SNARE proteins participating in exocytosis. Syntaxins possess a single C-terminal transmembrane domain...
    6 KB (702 words) - 21:34, 11 November 2024
  • Thumbnail for SNARE protein
    clasp releases closed syntaxin, remains associated with the N-terminal peptide of syntaxin (allowing association of the syntaxin SNARE domain with other...
    53 KB (6,592 words) - 21:23, 11 November 2024
  • Thumbnail for STX1A
    STX1A (redirect from Syntaxin 1A)
    presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxin-1A is a member of the syntaxin superfamily. Syntaxins are nervous system-specific...
    26 KB (2,987 words) - 12:06, 13 January 2024
  • Thumbnail for STX2
    STX2 (redirect from Syntaxin-2)
    Syntaxin-2, also known as epimorphin, is a protein that in humans is encoded by the STX2 gene. The product of this gene belongs to the syntaxin/epimorphin...
    10 KB (1,272 words) - 13:04, 15 January 2024
  • Thumbnail for Syntaxin 3
    Syntaxin 3, also known as STX3, is a protein which in humans is encoded by the STX3 gene. The protein encoded by this gene is a member of the syntaxin...
    12 KB (1,462 words) - 07:11, 10 March 2024
  • Thumbnail for STXBP1
    Syntaxin-binding protein 1 (also known as Munc18-1) is a protein that in humans is encoded by the STXBP1 gene. This gene encodes a syntaxin-binding protein...
    20 KB (2,189 words) - 02:11, 18 January 2024
  • Thumbnail for SNAP25
    family, and syntaxin-1 also help form the SNARE complex by each contributing a single α-helix. SNAP-25 assembles with synaptobrevin and syntaxin-1, and the...
    45 KB (5,006 words) - 08:04, 25 March 2024
  • Thumbnail for N-ethylmaleimide sensitive fusion protein
    fusion protein and alpha-SNAP induce a conformational change in syntaxin". The Journal of Biological Chemistry. 270 (28): 16955–61. doi:10.1074/jbc...
    14 KB (1,747 words) - 19:21, 13 August 2023
  • intermediate complex composed of SNAP-25 and syntaxin-1, which later accommodates synaptobrevin-2 (the quoted syntaxin and synaptobrevin isotypes participate...
    15 KB (1,822 words) - 18:40, 8 September 2024
  • Thumbnail for STX6
    Syntaxin-6 is a protein that in humans is encoded by the STX6 gene. STX6 has been shown to interact with SNAP23, VAMP3 and VAMP4. The protein domain Syntaxin...
    12 KB (1,378 words) - 06:26, 24 December 2023
  • Thumbnail for Exocytosis
    membranes together. For instance, in synapses, the SNARE complex is formed by syntaxin-1 and SNAP25 at the plasma membrane and VAMP2 at the vesicle membrane....
    15 KB (1,782 words) - 22:44, 19 August 2024
  • exocytosis of neurons and neuroendocrine cells. Munc-18 binds syntaxin and forms a syntaxin/munc-18 complex which is thought to precede and/or regulate...
    7 KB (804 words) - 00:07, 3 December 2023
  • Thumbnail for SNAP23
    termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of...
    17 KB (2,033 words) - 11:17, 15 January 2024
  • Thumbnail for VAMP2
    protein that in humans is encoded by the VAMP2 gene. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components...
    17 KB (1,958 words) - 20:32, 9 January 2024
  • Thumbnail for Syntaxin binding protein 3
    Syntaxin-binding protein 3 is a protein that in humans is encoded by the STXBP3 gene. Syntaxin binding protein 3 has been shown to interact with STX2 and...
    5 KB (571 words) - 14:21, 27 March 2022
  • Thumbnail for Syntaphilin
    Syntaphilin is a protein that in humans is encoded by the SNPH gene. Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which...
    1 KB (175 words) - 04:43, 27 December 2023
  • Thumbnail for Synaptic vesicle
    in this event. Munc13 is thought to stimulate the change of the t-SNARE syntaxin from a closed conformation to an open conformation, which stimulates the...
    34 KB (3,981 words) - 04:57, 17 September 2024
  • Thumbnail for STXBP5
    Syntaxin-binding protein 5 is a protein that in humans is encoded by the STXBP5 gene. It is also known as tomosyn, after 友, "friend" in Japanese, for its...
    6 KB (704 words) - 05:04, 1 December 2023
  • Thumbnail for Syntaxin binding protein 2
    Syntaxin-binding protein 2 is a protein that in humans is encoded by the STXBP2 gene. GRCh38: Ensembl release 89: ENSG00000076944 – Ensembl, May 2017 GRCm38:...
    6 KB (748 words) - 01:41, 16 March 2024
  • Thumbnail for NAPA (gene)
    p115/TAP, alpha-SNAP (this protein), gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other...
    12 KB (1,551 words) - 05:31, 15 January 2024
  • Thumbnail for Synaptobrevin
    of the core SNARE complex one is contributed by synaptobrevin, one by syntaxin, and two by SNAP-25 (in neurons). SNARE proteins are the key components...
    5 KB (507 words) - 06:01, 26 July 2023
  • Thumbnail for STX11
    Syntaxin 11, also known as STX11, is a human gene that is a member of the t-SNARE family. STX11 has been shown to interact with SNAP25 and SNAP23. Hemophagocytic...
    8 KB (1,063 words) - 19:54, 17 July 2023
  • Thumbnail for Hemophagocytic lymphohistiocytosis
    FHL2: PRF1 (Perforin) FHL3: UNC13D (Munc13-4) FHL4: STX11 (Syntaxin 11) FHL5: STXBP2 (Syntaxin binding protein 2)/UNC18-2 Nearly half of the cases of type...
    29 KB (3,306 words) - 22:34, 12 November 2024
  • Thumbnail for STED microscopy
    independently of the SNARE motif's functionality, and binds to clustered syntaxin. Studies of complex organelles, like mitochondria, also benefit from STED...
    33 KB (3,866 words) - 17:27, 8 June 2024
  • protein Maltose-binding protein Phosphatidylethanolamine binding protein 1 Syntaxin binding protein 3 Insulin-like growth factor-binding protein Methyl-CpG-binding...
    2 KB (263 words) - 21:49, 28 December 2020
  • Thumbnail for STX17
    Syntaxin 17 is a protein that in humans is encoded by the STX17 gene. In horses a duplication in intron 6 causes progressive graying. Syntaxin GRCh38:...
    3 KB (409 words) - 02:34, 28 March 2022
  • including vesicle-associated synaptobrevin and cell-membrane-associated syntaxin and SNAP. When the bundle is viewed on the side, for every alpha-helical...
    11 KB (1,319 words) - 15:22, 5 March 2024
  • and pseudohypoparathyroidism type Ib in mice with targeted disruption of syntaxin-16". Endocrinology. 148 (6): 2925–35. doi:10.1210/en.2006-1298. PMID 17317779...
    11 KB (944 words) - 12:37, 26 May 2024
  • Thumbnail for Cystic fibrosis transmembrane conductance regulator
    (September 2002). "CFTR chloride channels are regulated by a SNAP-23/syntaxin 1A complex". Proceedings of the National Academy of Sciences of the United...
    61 KB (6,477 words) - 12:46, 17 November 2024
  • Thumbnail for Synaptophysin
    PMID 10620806. S2CID 2623757. Nag TC, Wadhwa S (2001). "Differential expression of syntaxin-1 and synaptophysin in the developing and adult human retina". J. Biosci...
    13 KB (1,653 words) - 06:37, 22 June 2024