• Thumbnail for TGF alpha
    growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. As a member of the epidermal growth factor (EGF) family, TGF-α is a mitogenic...
    16 KB (2,040 words) - 11:11, 4 January 2024
  • Thumbnail for Transforming growth factor beta
    (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different mammalian isoforms (TGF-β...
    70 KB (8,485 words) - 08:12, 19 May 2024
  • Thumbnail for TGF beta 1
    and other functions in many cell types. TGF-β acts synergistically with transforming growth factor-alpha (TGF-α) in inducing transformation. It also acts...
    19 KB (2,290 words) - 20:43, 26 March 2024
  • Thumbnail for TGF beta receptor 1
    syndrome (LDS, LDAS). TGF beta receptor 1 has been shown to interact with: Caveolin 1, Endoglin, FKBP1A, FNTA, Heat shock protein 90kDa alpha (cytosolic), member...
    14 KB (1,618 words) - 02:37, 2 April 2024
  • Thumbnail for Juxtacrine signalling
    al. (1990) to describe a possible way of signal transduction between TGF alpha and EGFR. In this type of signaling, specific membrane-bound ligands bind...
    12 KB (1,361 words) - 06:13, 15 April 2024
  • Thumbnail for Colostrum
    Okada M, Ohmura E, Kamiya Y, et al. (1991). "Transforming growth factor (TGF)-alpha in human milk". Life Sciences. 48 (12): 1151–1156. doi:10.1016/0024-3205(91)90452-H...
    53 KB (6,125 words) - 06:00, 3 July 2024
  • contributions to several neuroscientific subjects, including the discoveries of TGF alpha and epidermal growth factor. He was the first to show large-scale stimulation...
    9 KB (948 words) - 18:34, 12 March 2024
  • Thumbnail for Skin
    life. It is maintained as a stem cell layer through an autocrine signal, TGF alpha, and through paracrine signaling from FGF7 (keratinocyte growth factor)...
    36 KB (4,279 words) - 20:58, 22 June 2024
  • Transforming growth factor beta (TGF-β) is a potent cell regulatory polypeptide homodimer of 25kD. It is a multifunctional signaling molecule with more...
    20 KB (2,419 words) - 09:58, 28 June 2024
  • Thumbnail for TGF beta receptor 2
    TGF beta receptor 2 has been shown to interact with: AP2B1, Cyclin B2, Endoglin, Heat shock protein 90kDa alpha (cytosolic), member A1 STRAP, TGF beta...
    9 KB (960 words) - 00:24, 4 January 2024
  • Thumbnail for Integrin beta 6
    JS, Rifkin DB (June 2004). "Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1". The Journal of...
    35 KB (4,041 words) - 17:11, 23 December 2023
  • Thumbnail for Alveolar macrophage
    Integrins are dimeric cell-surface receptors composed of alpha and beta subunits, which activates TGF-β.< TGF-β is a multifunctional cytokine that modulates a...
    33 KB (3,862 words) - 16:23, 12 June 2024
  • Thumbnail for Epidermal growth factor
    Heparin-binding EGF-like growth factor (HB-EGF) transforming growth factor-α (TGF-α) Amphiregulin (AR) Epiregulin (EPR) Epigen Betacellulin (BTC) neuregulin-1...
    17 KB (1,735 words) - 03:22, 28 February 2024
  • Thumbnail for Bone metastasis
    paraneoplastic effects, such as via the secretion of prostaglandin E, TGF-alpha, TGF-beta, TNF, and interleukins to increase bone resorption. The destruction...
    25 KB (2,653 words) - 20:55, 22 May 2024
  • Thumbnail for Alpha granule
    Contents include insulin-like growth factor 1, platelet-derived growth factors, TGF beta, platelet factor 4 (which is a heparin-binding chemokine) and other...
    4 KB (349 words) - 11:47, 13 August 2023
  • affinity for both homodimeric TGFβ1 and TGFβ2 and in addition the heterodimer TGF-β1.2. The TGFβ receptors also bind TGFβ3. TGFβ superfamily receptor TGFβ...
    4 KB (334 words) - 01:11, 14 December 2022
  • Agency, an executive agency of Tanzania that provides VIP flight service TGF alpha, a human protein This disambiguation page lists articles associated with...
    180 bytes (54 words) - 15:39, 30 December 2019
  • Thumbnail for AP-1 transcription factor
    supporting its suggested involvement in the cell cycle. The growth factors TGF alpha, TGF beta, and IL2 have all been shown to stimulate c-Fos, and thereby stimulate...
    41 KB (4,463 words) - 15:48, 8 June 2024
  • Thumbnail for Endocrine disruptor
    P, Bai ZP (April 2008). "Expression of AhR, CYP1A1, GSTA1, c-fos and TGF-alpha in skin lesions from dioxin-exposed humans with chloracne" (PDF). Toxicol...
    146 KB (16,616 words) - 19:41, 27 April 2024
  • Thumbnail for Epidermal growth factor receptor
    ligands, including epidermal growth factor and transforming growth factor alpha (TGF-α). ErbB2 has no known direct activating ligand, and may be in an activated...
    60 KB (6,879 words) - 09:57, 15 January 2024
  • Thumbnail for ACTA2
    ACTA2 (redirect from Alpha smooth muscle)
    as alpha-smooth muscle actin or α-SMA) is often used as a marker of myofibroblast formation. Studies have shown that ACTA2 is associated with TGF-β pathway...
    9 KB (1,136 words) - 03:07, 6 May 2024
  • cytoprotective PG2 cytoprotective ECF helps gut maturation TGF-alpha promotes the growth of epithelial tissue TGF-beta Il-10 (a cytokine) TGF-alpha; RI,RII...
    2 KB (46 words) - 16:38, 29 June 2023
  • Thumbnail for TGF beta 2
    of transforming growth factor-beta (TGF-beta) to pregnancy zone protein (PZP). Comparison to the TGF-beta-alpha 2-macroglobulin interaction". Eur. J...
    7 KB (910 words) - 16:22, 14 August 2023
  • receptors involved in TGF beta signaling pathway. These receptors bind growth factor and cytokine signaling proteins in the TGF-beta family such as TGFβs...
    5 KB (468 words) - 03:56, 29 November 2023
  • Thumbnail for Alpha-2-Macroglobulin
    such as platelet-derived growth factor, basic fibroblast growth factor, TGF-β, insulin, and IL-1β. No specific deficiency with associated disease has...
    14 KB (1,631 words) - 05:36, 8 March 2024
  • Thumbnail for Tumor necrosis factor
    Szondy Z, Pallai A (January 2017). "Transmembrane TNF-alpha reverse signaling leading to TGF-beta production is selectively activated by TNF targeting...
    52 KB (6,302 words) - 07:19, 27 April 2024
  • Thumbnail for TBRG1
    "Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta". Mol Reprod Dev. 41 (2): 133–9. doi:10.1002/mrd.1080410203....
    3 KB (439 words) - 00:52, 4 March 2023
  • Thumbnail for FNDC5
    hormones and hormone-like polypeptides, such as epidermal growth factor and TGF alpha, from transmembrane precursors. After the N-terminal signal peptide is...
    20 KB (2,181 words) - 12:13, 28 June 2024
  • Thumbnail for Insulin-degrading enzyme
    have additional substrates, including the signaling peptides glucagon, TGF alpha, and β-endorphin. Considerable interest in IDE has been stimulated due...
    17 KB (2,076 words) - 04:47, 3 June 2024
  • Thumbnail for Transforming growth factor, beta 3
    which includes the TGF-β family, Bone morphogenetic proteins (BMPs), growth and differentiation factors (GDFs), inhibins and activins. TGF-β3 is believed...
    15 KB (1,815 words) - 23:18, 18 August 2023