• biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating...
    54 KB (6,343 words) - 14:14, 17 June 2024
  • Post-transcriptional regulation is the control of gene expression at the RNA level. It occurs once the RNA polymerase has been attached to the gene's promoter...
    27 KB (3,383 words) - 01:17, 8 September 2024
  • Thumbnail for Regulation of gene expression
    analysis Due to post-transcriptional regulation, transcription rates and total RNA levels differ significantly. To measure the transcription rates nuclear run-on...
    45 KB (5,236 words) - 14:22, 7 October 2024
  • Thumbnail for Transcription (biology)
    to 800 genes are transcriptionally inhibited by CpG island methylation (see regulation of transcription in cancer). Transcriptional repression in cancer...
    58 KB (6,787 words) - 20:17, 9 August 2024
  • Thumbnail for Gene expression
    to 800 genes are transcriptionally silenced by CpG island methylation (see regulation of transcription in cancer). Transcriptional repression in cancer...
    102 KB (11,438 words) - 16:50, 17 July 2024
  • Thumbnail for Antisense RNA
    asRNA dependent regulation is not limited to on/off mechanism; rather, it presents a fine tone control system. The direct post transcriptional modulation by...
    24 KB (2,997 words) - 00:53, 25 July 2024
  • Thumbnail for Eukaryotic transcription
    portal Bacterial transcription Regulation of gene expression RNA polymerase Transcriptional regulation Transcription factor Transcriptional memory Watson...
    49 KB (5,861 words) - 10:12, 12 August 2024
  • Thumbnail for Transcription factor
    its DNA-binding sites, changing the transcriptional regulation of the associated genes. Not only do transcription factors act downstream of signaling...
    73 KB (8,057 words) - 16:30, 24 September 2024
  • Thumbnail for Granulopoiesis
    C/EBPε and GFI-1, these two transcriptional factors are important for terminal granulocyte differentiation. Other transcriptional factors that regulate granulopoiesis...
    18 KB (1,916 words) - 05:42, 17 August 2024
  • is moderated by SREBP-1. The effect of glucose and insulin on the transcriptional factor can occur through various pathways; there is evidence suggesting...
    17 KB (2,179 words) - 16:33, 17 August 2024
  • Thumbnail for Sodium/iodide cotransporter
    depends on TSH, which acts by transcriptional and posttranslational mechanisms. On the other hand, negative regulation depends on the plasmatic concentrations...
    27 KB (3,135 words) - 03:34, 26 August 2024
  • Transcriptional addiction is a concept in cancer biology where cancer cells become heavily reliant on abnormal transcriptional programs to sustain their...
    6 KB (789 words) - 11:22, 4 October 2024
  • Thumbnail for CTCF
    CTCF (category Transcription factors)
    many cellular processes, including transcriptional regulation, insulator activity, V(D)J recombination and regulation of chromatin architecture. CCCTC-Binding...
    26 KB (3,172 words) - 03:27, 3 December 2023
  • Thumbnail for Aspergillus fumigatus
    Bok JW, Cramer RA, Wortman JR, Kim HS, et al. (April 2007). "Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA". PLOS...
    44 KB (4,593 words) - 21:58, 22 August 2024
  • S2CID 27163437. Brunner M, Schafmeier T (May 2006). "Transcriptional and post-transcriptional regulation of the circadian clock of cyanobacteria and Neurospora"...
    37 KB (4,473 words) - 07:35, 3 June 2024
  • Thumbnail for Silencer (genetics)
    Ogbourne, Steven; Toni Antalis (1998). "Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes". Biochem. J. 331 (1):...
    27 KB (3,340 words) - 20:01, 8 June 2024
  • differentiation. In comparison to transcriptional regulation, it results in much more immediate cellular adjustment through direct regulation of protein concentration...
    11 KB (1,481 words) - 11:25, 11 February 2024
  • Thumbnail for Long non-coding RNA
    extensively reported to be involved in ceRNA regulation, transcriptional regulation, and epigenetic regulation. A further large-scale sequencing study provides...
    115 KB (12,353 words) - 17:28, 3 October 2024
  • Thumbnail for Ubiquitin
    Rosenfeld MG (January 2009). "Histone H2A ubiquitination in transcriptional regulation and DNA damage repair". The International Journal of Biochemistry...
    97 KB (11,021 words) - 17:45, 18 September 2024
  • Thumbnail for Staphylococcus aureus
    (October 2014). "Contribution of teg49 small RNA in the 5' upstream transcriptional region of sarA to virulence in Staphylococcus aureus". Infection and...
    114 KB (12,721 words) - 16:39, 4 October 2024
  • Thumbnail for Epigenetics
    chromatin-based transcriptional regulation could be mediated by the effect of small RNAs. Small interfering RNAs can modulate transcriptional gene expression...
    161 KB (18,346 words) - 02:11, 20 August 2024
  • within the 5′ UTR. In addition, this region has been involved in transcription regulation, such as the sex-lethal gene in Drosophila. Regulatory elements...
    21 KB (2,428 words) - 20:42, 3 June 2024
  • Thumbnail for CRISPR interference
    minimal system for gene-specific regulation. CRISPRi can sterically repress transcription by blocking either transcriptional initiation or elongation. This...
    24 KB (2,898 words) - 12:08, 22 March 2024
  • Thumbnail for Lactate dehydrogenase
    into lactate. LDH undergoes transcriptional regulation by PGC-1α. PGC-1α regulates LDH by decreasing LDH A mRNA transcription and the enzymatic activity...
    42 KB (4,795 words) - 21:02, 11 June 2024
  • Thumbnail for NPM1
    (Skaar et al., 1998). Moreover, NPM1 is a direct transcriptional target of oncogenic transcription factor c-myc (Zeller et al., 2001). The ability of...
    39 KB (4,897 words) - 09:09, 9 April 2024
  • Thumbnail for Plant evolution
    proposes that this Co-location is required for Redox Regulation. Transcription factors and transcriptional regulatory networks play key roles in plant development...
    16 KB (1,784 words) - 09:44, 9 April 2024
  • Thumbnail for G0 phase
    to play an important role in maintenance of quiescence. Post-transcriptional regulation of gene expression via miRNA synthesis has been shown to play...
    30 KB (3,755 words) - 01:51, 4 April 2024
  • Thumbnail for Adipogenesis
    Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM (June 2000). "Transcriptional regulation of adipogenesis". Genes & Development. 14 (11): 1293–307. doi:10...
    24 KB (2,438 words) - 11:40, 21 February 2024
  • division. Transcription by RNA polymerase also generates positive supercoiling ahead of, and negative supercoiling behind, the transcriptional complex (Fig...
    57 KB (6,173 words) - 00:11, 11 December 2023
  • to repress and activate transcription in a cell. Transcriptional regulation additionally focuses on the epigenetic regulation of a target locus, as the...
    14 KB (1,730 words) - 22:12, 19 May 2024