• Thumbnail for Signal transduction
    Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events. Proteins responsible...
    63 KB (7,609 words) - 04:41, 21 June 2024
  • Thumbnail for Two-component regulatory system
    "conspicuously absent" from animals. Two-component systems accomplish signal transduction through the phosphorylation of a response regulator (RR) by a histidine...
    26 KB (2,790 words) - 01:31, 31 March 2024
  • promoted. The effector component of the signaling pathway begins with signal transduction. In this process, the signal, by interacting with the receptor, starts...
    62 KB (6,781 words) - 02:30, 5 July 2024
  • Thumbnail for Paracrine signaling
    Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses. In order for paracrine factors...
    46 KB (4,967 words) - 21:12, 7 July 2024
  • Thumbnail for G protein
    their discovery of "G-proteins and the role of these proteins in signal transduction in cells". The 2000 Nobel Prize in Physiology or Medicine to Eric...
    24 KB (2,753 words) - 17:58, 19 June 2024
  • Thumbnail for Calcium signaling
    Calcium signaling is the use of calcium ions (Ca2+) to communicate and drive intracellular processes often as a step in signal transduction. Ca2+ is important...
    19 KB (2,271 words) - 18:47, 25 March 2024
  • Thumbnail for Ethylene signaling pathway
    Ethylene signaling pathway is a signal transduction in plant cells to regulate important growth and developmental processes. Acting as a plant hormone...
    24 KB (2,898 words) - 12:51, 6 July 2024
  • Thumbnail for Hormone
    Hormone (redirect from Hormone signalling)
    protein. Relay and amplification of the received hormonal signal via a signal transduction process: This then leads to a cellular response. The reaction...
    40 KB (4,212 words) - 11:57, 25 June 2024
  • Thumbnail for Notch signaling pathway
    resource of signal transduction pathways in humans Artavanis-Tsakonas S, Rand MD, Lake RJ (April 1999). "Notch signaling: cell fate control and signal integration...
    88 KB (10,270 words) - 03:00, 22 June 2024
  • Thumbnail for Cell surface receptor
    Cell surface receptor (category Cell signaling)
    changes in the metabolism and activity of a cell. In the process of signal transduction, ligand binding affects a cascading chemical change through the cell...
    21 KB (2,456 words) - 22:14, 21 November 2023
  • Thumbnail for GRB2
    GRB2 (category Signal transduction)
    protein 2, also known as Grb2, is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the...
    82 KB (9,365 words) - 15:39, 31 March 2024
  • Temporal feedback (category Signal transduction)
    trigger, polarization in budding yeast, mammalian calcium signal transduction, EGF receptor signaling, platelet activation, and Xenopus oocyte maturation are...
    7 KB (925 words) - 04:41, 26 February 2024
  • Thumbnail for G protein-coupled receptor
    G protein-coupled receptor (category Signal transduction)
    principal signal transduction pathways involving the G protein-coupled receptors: the cAMP signal pathway and the phosphatidylinositol signal pathway....
    82 KB (9,384 words) - 18:56, 11 June 2024
  • Functional selectivity (category Signal transduction)
    agonism”, “biased signaling”, "ligand bias" and “differential engagement”) is the ligand-dependent selectivity for certain signal transduction pathways relative...
    17 KB (1,848 words) - 23:24, 8 July 2024
  • Thumbnail for Organ of Corti
    strip of epithelial cells allows for transduction of auditory signals into nerve impulses' action potential. Transduction occurs through vibrations of structures...
    17 KB (2,095 words) - 05:40, 26 October 2023
  • Thumbnail for ANKK1
    ANKK1 (category Signal transduction)
    protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene contains a single nucleotide polymorphism that...
    9 KB (1,105 words) - 16:23, 29 January 2023
  • Thumbnail for Imd pathway
    Imd pathway (category Signal transduction)
    The Imd pathway is a broadly-conserved NF-κB immune signalling pathway of insects and some arthropods that regulates a potent antibacterial defence response...
    23 KB (2,455 words) - 19:21, 2 April 2024
  • Thumbnail for Toll-like receptor
    immune mechanisms on signal transduction. The fly response to fungal or bacterial infection occurs through two distinct signalling cascades, one of which...
    60 KB (6,685 words) - 08:19, 24 June 2024
  • Thumbnail for Sphingomyelin
    significant roles in signaling pathways: the degradation and synthesis of sphingomyelin produce important second messengers for signal transduction. Sphingomyelin...
    17 KB (1,972 words) - 21:12, 19 May 2024
  • independent MAP kinase signal transduction pathways. The acronym MEK derives from MAPK/ERK Kinase. MEK is a member of the MAPK signaling cascade that is activated...
    3 KB (296 words) - 17:06, 14 September 2023
  • Because certain signal transduction pathways oppose the STAT3-Ser/Hes3 signaling axis, blockers (inhibitors) of these signal transduction pathways promote...
    26 KB (3,339 words) - 02:29, 10 February 2024
  • Thumbnail for Glycoprotein 130
    often referred to as the common gp130 subunit, and is important for signal transduction following cytokine engagement. As with other type I cytokine receptors...
    18 KB (2,202 words) - 01:16, 14 June 2024
  • Phosphatidic acid (category Signal transduction)
    DN, Waggoner DW (May 1996). "Phosphatidate phosphohydrolase and signal transduction". Chem. Phys. Lipids. 80 (1–2): 45–57. doi:10.1016/0009-3084(96)02545-5...
    25 KB (3,086 words) - 00:31, 3 December 2023
  • intracellular signaling cascades, termed signal transduction pathways, that regulate specific cellular functions. Each signal transduction occurs with a...
    99 KB (11,432 words) - 18:01, 29 April 2024
  • Thumbnail for Apoptosis
    Caspases are Regulated in Human Myeloid HL-60 Cells by Calcium Signal". Current Signal Transduction Therapy. 5 (2): 181–186. doi:10.2174/157436210791112172....
    91 KB (10,659 words) - 02:42, 7 July 2024
  • Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine...
    18 KB (2,105 words) - 17:15, 1 December 2023
  • tissue level, including cellular recognition, plant perception, plant signal transduction, intercellular communication, immunological processes, etc. The term...
    2 KB (246 words) - 00:25, 23 March 2023
  • GTPase (category Signal transduction)
    fundamental cellular processes. Examples of these roles include: Signal transduction in response to activation of cell surface receptors, including transmembrane...
    20 KB (2,306 words) - 18:17, 15 July 2024
  • post-transduction signal processing that differentiates their responses. However, little is known about the specifics of either of these signaling mechanisms...
    22 KB (2,643 words) - 18:11, 21 January 2024
  • Thumbnail for PI3K/AKT/mTOR pathway
    PI3K/AKT/mTOR pathway (category Signal transduction)
    inhibition: co-targeted therapeutic approaches in prostate cancer". Signal Transduction and Targeted Therapy. 5: 7. doi:10.1038/s41392-020-0109-y. ISSN 2059-3635...
    36 KB (4,322 words) - 16:42, 6 October 2023