Polyubiquitin-C is a protein encoded by the UBC gene in humans. Polyubiquitin-C is one of the sources of ubiquitin, along with UBB, UBA52, and RPS27A....
37 KB (4,261 words) - 21:30, 23 December 2023
Ubiquitin is a small (8.6 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e., it is found ubiquitously. It was discovered in...
98 KB (11,068 words) - 18:53, 17 August 2024
Ubiquitin carboxy-terminal hydrolase L1 (EC 3.1.2.15, ubiquitin C-terminal hydrolase, UCH-L1) is a deubiquitinating enzyme. UCH-L1 is a member of a gene...
21 KB (2,637 words) - 03:01, 26 November 2023
A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin...
24 KB (2,754 words) - 17:41, 3 September 2024
Ubiquitin C-terminal hydrolase may refer to: Ubiquitin carboxy-terminal hydrolase L1, an enzyme Ubiquitinyl hydrolase 1, an enzyme This set index page...
459 bytes (52 words) - 13:45, 6 February 2015
ubiquitin proteases, ubiquitin hydrolases, or ubiquitin isopeptidases, are a large group of proteases that cleave ubiquitin from proteins. Ubiquitin is...
37 KB (4,309 words) - 13:07, 12 July 2024
Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which (among other things) can target...
9 KB (1,051 words) - 15:40, 31 December 2023
Ubiquitin is a protein that in humans is encoded by the UBB gene. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin...
8 KB (996 words) - 21:12, 21 June 2024
Proteasome (redirect from Ubiquitin proteosome system)
Proteasomes are protein complexes which degrade ubiquitin-tagged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that...
105 KB (12,670 words) - 08:02, 23 August 2024
Ubiquitinyl hydrolase 1 (redirect from Yeast ubiquitin hydrolase)
Ubiquitinyl hydrolase 1 (EC 3.4.19.12, ubiquitin C-terminal hydrolase, yeast ubiquitin hydrolase) is an enzyme. This enzyme catalyses the following chemical...
1 KB (150 words) - 16:12, 26 August 2023
encodes a fusion protein consisting of ubiquitin at the N-terminus and ribosomal protein L40 at the C-terminus, a C-terminal extension protein (CEP). Multiple...
6 KB (825 words) - 04:26, 28 November 2023
Ub-AMC (redirect from Ubiquitin-AMC)
Ubiquitin-AMC is a fluorogenic substrate for a wide range of deubiquitinating enzymes (DUBs), including ubiquitin C-terminal hydrolases (UCHs) and ubiquitin...
2 KB (274 words) - 08:53, 18 May 2024
Parkin is a 465-amino acid residue E3 ubiquitin ligase, a protein that in humans and mice is encoded by the PARK2 gene. Parkin plays a critical role in...
47 KB (5,731 words) - 11:29, 22 June 2024
SUMO protein (redirect from Small ubiquitin-like modifier)
In molecular biology, SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other...
22 KB (2,753 words) - 18:34, 26 March 2024
UBB+1 is shorthand for Ubiquitin-B+1, a frameshifted mutant arising from the Ubiquitin B gene. UBB+1 is thought to arise from molecular misreading, a...
3 KB (324 words) - 12:05, 11 December 2023
chr17 PFDN5 ENST00000334478 Prefoldin subunit 5 chr12 RHOA ENST00000418115 Ras homolog family member A chr3 ubiquitin C ENST00000546120 Ubiquitin C chr12...
5 KB (486 words) - 19:42, 11 September 2022
Kobeissy F, Shakkour Z, Tyndall J (19 Jan 2021). "Thorough overview of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein as tandem biomarkers...
49 KB (6,133 words) - 17:01, 26 July 2024
activation process by E1, an ATP-dependent ubiquitin activating enzyme. The carboxyl terminal (C-terminus) of ubiquitin is linked to the cysteine residue of...
17 KB (2,244 words) - 11:45, 4 January 2024
Broadcasting Corporation, a cable television company in Thailand Ubiquitin C, a human gene Ubiquitin-conjugating enzyme Ultra Bright Colour, a mobile phone display...
2 KB (308 words) - 23:00, 27 March 2024
Kobeissy F, Shakkour Z, Tyndall J (January 19, 2021). "Thorough overview of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein as tandem biomarkers...
38 KB (4,442 words) - 03:39, 7 August 2024
found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydrolases. This reaction is important for the treatment of...
6 KB (637 words) - 00:28, 8 December 2023
Leeuwen FW (July 2011). "Mutant ubiquitin (UBB(+1)) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)"...
5 KB (691 words) - 07:42, 11 December 2023
been shown to interact with sodium-hydrogen antiporter 3 regulator 1, ubiquitin C, 5-HT1A receptor, and RGS12. δ-opioid receptor μ-opioid receptor Nociceptin...
67 KB (7,676 words) - 03:02, 15 August 2024
Prokaryotic ubiquitin-like protein (Pup) is a functional analog of ubiquitin found in the prokaryote Mycobacterium tuberculosis. Like ubiquitin, Pup serves...
16 KB (1,725 words) - 03:48, 26 July 2022
Housekeeping gene (section Cytochrome C oxidase)
sapiens ubiquitin B (UBB), mRNA UBC NM_021009 Homo sapiens ubiquitin C (UBC), mRNA UBE2A NM_003336 UBE2B NM_003337 UBE2D2 NM_003339 Homo sapiens ubiquitin-conjugating...
48 KB (4,612 words) - 23:41, 12 December 2023
LUBAC (redirect from Linear ubiquitin chain assembly complex)
Linear ubiquitin chain assembly complex (LUBAC) is a multi-protein complex and the only known E3 ubiquitin ligase able to conjugate ubiquitin in a head-to-tail...
12 KB (1,247 words) - 08:33, 18 August 2023
1177/19458924221120117. PMC 9379596. PMID 35957578. Zhang R, Sun C, Chen X, Han Y, Zang W, Jiang C, et al. (April 2022). "COVID-19-Related Brain Injury: The...
58 KB (6,693 words) - 21:39, 11 August 2024
Ubiquitin-like proteins (UBLs) are a family of small proteins involved in post-translational modification of other proteins in a cell, usually with a...
28 KB (3,106 words) - 23:32, 15 December 2023
The ubiquitin carboxyl-terminal hydrolase 27 (EC 3.4.19.12), also known as deubiquitinating enzyme 27, ubiquitin thioesterase 27 and USP27X, is a deubiquitinating...
18 KB (2,080 words) - 09:54, 4 January 2024
MSH6 MUTYH P21 POLD2 POLD3 POLDIP2 POLH POLL RFC1 RFC2 RFC3 RFC4 RFC5 Ubiquitin C Werner syndrome ATP-dependent helicase XRCC1 Y box binding protein 1...
53 KB (6,158 words) - 18:54, 23 April 2024