Vigabatrin, sold under the brand name Sabril among others, is a medication used in the management and treatment of infantile spasms and refractory complex...
27 KB (2,563 words) - 19:50, 27 September 2024
adrenocorticotropic hormone (ACTH) or glucocorticoids (prednisone), or vigabatrin. Ketogenic diet may be effective as second-line therapy for treatment-resistant...
20 KB (1,887 words) - 02:53, 9 October 2024
increased neuronal GABA concentrations. Examples include valproic acid, vigabatrin, phenylethylidenehydrazine (and drugs that metabolize to it, such as phenelzine)...
4 KB (341 words) - 21:12, 2 September 2023
Some specific anticonvulsant drugs such as phenytoin, carbamazepine, and vigabatrin have been identified to raise the chances of experiencing absence seizures...
30 KB (3,581 words) - 20:14, 8 September 2024
valproate, and divalproex sodium (1967). Vigabatrin (1989). Progabide (1987). Tiagabine (1996). Vigabatrin and progabide are also analogs of GABA. Topiramate...
70 KB (5,714 words) - 11:37, 30 September 2024
other adjunctive therapies. Use is restricted due to hepatotoxicity. Vigabatrin — used only in extreme treatment-resistant epilepsy due to the risk of...
16 KB (1,856 words) - 11:26, 27 July 2024
one that reduces the levels of GHB via inhibition of GABA transaminase. Vigabatrin is an irreversible inhibitor of GABA transaminases which leads to decreased...
33 KB (3,995 words) - 12:28, 15 April 2024
The study concluded that LGS accounts for 4% of childhood epilepsies. Vigabatrin was found by Feucht et al. to be an effective add-on in patients whose...
30 KB (3,424 words) - 21:02, 22 September 2024
Trimipramine Troglitazone Valdecoxib Sodium valproate Venlafaxine Veralipride Vigabatrin Vilazodone Vortioxetine Ziprasidone Zotepine Zuclopenthixol Acitretin...
26 KB (1,722 words) - 21:40, 3 October 2024
Phenelzine Phenylethylidenehydrazine (PEH) Rosmarinic acid Valproic acid Vigabatrin "4-aminobutyrate aminotransferase - Identical Protein Groups - NCBI"....
14 KB (1,523 words) - 10:55, 18 October 2023
of epilepsy in TSC patients include mTOR inhibitors, cannabidiol and vigabatrin. Epilepsy surgery is often pursued. Sturge-Weber syndrome is caused by...
168 KB (18,337 words) - 04:05, 6 October 2024
Pivagabine (N-pivaloyl-GABA) – antidepressant/anxiolytic drug; CRF inhibitor Vigabatrin (y-vinyl-GABA) – anticonvulsant; GABA-T inhibitor Bamaluzole Bicuculline...
8 KB (754 words) - 04:40, 27 January 2024
transporter Inhibitors: β-Alanine Bafilomycin A1 Chicago sky blue 6B Evans blue GABA Glycine N-Butyric acid Nigericin Nipecotic acid Valinomycin Vigabatrin...
13 KB (1,391 words) - 03:12, 25 June 2024
in the preparation of several medicinally useful compounds including vigabatrin, phenylbutazone, nalidixic acid, and rebamipide. Several pesticides are...
9 KB (765 words) - 20:59, 8 February 2024
enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin". The Journal of Biological Chemistry. 279 (1): 363–373. doi:10.1074/jbc...
29 KB (2,814 words) - 03:50, 13 August 2024
(often with mood changes in addition), and some anticonvulsants such as vigabatrin. The first brain image of an individual with psychosis was completed as...
133 KB (14,931 words) - 18:38, 25 September 2024
and Stimulator" Lu AA21004: How Novel? How Good? - GLG News". "Sabril (vigabatrin) Tablets. Prescribing information." Lundbeck Inc., 2012. Revised February...
17 KB (1,121 words) - 21:58, 12 September 2024
Vesicular inhibitory amino acid transporter β-Alanine Bafilomycin A1 Butyric acid Evans blue GABA Glycine Nigericin Nipecotic acid Valinomycin Vigabatrin...
21 KB (1,748 words) - 12:42, 5 August 2024
(Prednisolone), for multiple sclerosis. Rilutek (Riluzole), for ALS. Sabril (Vigabatrin), for epilepsy, marketed by Lundbeck. – Oncology Anzemet (Dolasetron)...
92 KB (8,810 words) - 04:11, 13 September 2024
reference the compound is called a 'suicide inactivator' (not inhibitor). Vigabatrin, an anticonvulsant, is a suicide inhibitor of GABA-T. Suicide inhibitors...
5 KB (588 words) - 20:27, 18 September 2024
transporter Inhibitors: β-Alanine Bafilomycin A1 Chicago sky blue 6B Evans blue GABA Glycine N-Butyric acid Nigericin Nipecotic acid Valinomycin Vigabatrin...
37 KB (3,825 words) - 21:25, 7 October 2024
but it may offer a safety advantage. Newer AEDs, including lacosamide, vigabatrin, felbamate, gabapentin, tiagabine, and rufinamide have been found to be...
40 KB (3,797 words) - 04:47, 25 July 2024
medicine, Desoxyn (brand name for methamphetamine hydrochloride), and vigabatrin, an anticonvulsant that inhibits the catabolism of GABA and is indicated...
5 KB (464 words) - 09:02, 31 July 2024
(PIGO). anticonvulsants (such as phenytoin, phenobarbital, lamotrigine, vigabatrin, ethosuximide, topiramate and primidone NOT common for valproate) calcium...
15 KB (1,612 words) - 19:38, 22 August 2024
needed] GABA transaminase inhibitors: gabaculine, phenelzine, valproate, vigabatrin, lemon balm (Melissa officinalis). GABA analogues: pregabalin, gabapentin...
51 KB (5,567 words) - 00:03, 9 September 2024
gamma-Aminobutyric acid (GABA) GABA reuptake inhibitors tiagabine, St John's wort, vigabatrin, deramciclane GABAA receptor agonists ethanol, niacin, barbiturates, diazepam...
84 KB (8,288 words) - 08:54, 14 September 2024
transporter Inhibitors: β-Alanine Bafilomycin A1 Chicago sky blue 6B Evans blue GABA Glycine N-Butyric acid Nigericin Nipecotic acid Valinomycin Vigabatrin...
93 KB (8,024 words) - 20:00, 24 September 2024
(and hence also an indirect and non-selective GABA receptor agonist) vigabatrin has also been associated with acute psychotic episodes, hallucinations...
11 KB (1,020 words) - 07:50, 6 January 2024
Vesicular inhibitory amino acid transporter β-Alanine Bafilomycin A1 Butyric acid Evans blue GABA Glycine Nigericin Nipecotic acid Valinomycin Vigabatrin...
89 KB (9,448 words) - 10:19, 5 October 2024
Vesicular inhibitory amino acid transporter β-Alanine Bafilomycin A1 Butyric acid Evans blue GABA Glycine Nigericin Nipecotic acid Valinomycin Vigabatrin...
6 KB (316 words) - 08:08, 5 July 2024