α-Methyl-p-tyrosine (AMPT), or simply α-methyltyrosine, also known in its chiral 2-(S) form as metirosine, is a tyrosine hydroxylase enzyme inhibitor and...
24 KB (2,255 words) - 12:06, 8 October 2024
α-Methyl-5-hydroxytryptophan (α-Me-5-HTP) is a synthetic tryptamine derivative, an artificial amino acid, and a prodrug of α-methylserotonin. It is the...
10 KB (786 words) - 03:51, 14 October 2024
(para-chlorophenylalanine) Metirosine (α-methyl-para-tyrosine) Methyldopa (α-methyl-DOPA) α-Methyltryptophan 3,4-Dihydroxystyrene "alpha-methyl-L-phenylalanine". PubChem...
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9-Methyl-β-carboline (9-Me-BC) is a heterocyclic amine of the β-carboline family, and a research chemical. 9-Me-BC is a methylated derivative of β-carboline...
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αMTP is a viable agent for such purposes. αMTP is first converted by tryptophan hydroxylase into α-methyl-5-hydroxytryptophan (αM-5-HTP or α-methyl-5-HTP)...
12 KB (1,157 words) - 03:09, 14 October 2024
it gets serially demethylated and forms all the tri-, di-, mono- and non-methyl intermediates, which are Azure B, Azure A, Azure C, and thionine, respectively...
47 KB (5,008 words) - 19:20, 15 October 2024
Catechol-O-methyltransferase (redirect from Catechol-o-methyl transferase)
neurotransmitters (dopamine, epinephrine, and norepinephrine). The enzyme introduces a methyl group to the catecholamine, which is donated by S-adenosyl methionine (SAM)...
29 KB (3,236 words) - 00:14, 10 July 2024
to tyrosine hydroxylase could be generated by the tyrosine hydroxylase system itself. Tyrosine hydroxylase can be inhibited by the drug α-methyl-para-tyrosine...
37 KB (4,405 words) - 16:27, 9 October 2024
acid • Nepicastat • Phenopicolinic acid • Tropolone L-Phenylalanine → L-tyrosine → L-DOPA (levodopa) Ferrous iron (Fe2+) • Tetrahydrobiopterin • Vitamin...
16 KB (845 words) - 15:11, 27 September 2024
7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole Harmine is a reversible inhibitor of monoamine oxidase A (RIMA). Harmaline: C13H14N2O 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3...
14 KB (1,526 words) - 03:35, 8 September 2024
(5-MeO-αMT), α,N-dimethyltryptamine (α,N-DMT; N-methyl-αMT), α,N,N-trimethyltryptamine (α,N,N-TMT; N-dimethyl-αMT), α-methylserotonin (α-methyl-5-HT; 5-hydroxy-αMT)...
40 KB (3,622 words) - 09:10, 9 October 2024
& Zhou 2004, p. 26. "Guindon & Boisclair" 2004, pp. 13–16. Samet & Yoon 2001, p. 5-6. Surgeon General's Report Women and Smoking 2001, p. 47. "WHO/WPRO-Tobacco"...
103 KB (10,986 words) - 06:41, 16 September 2024
Pharmacology from H.P. Rang, M.M. Dale, J.M. Ritter, P.K. Moore, year 2003, chapter 38 "MHRA PAR Dextromethorphan hydrobromide, p. 12" (PDF). Archived...
37 KB (4,010 words) - 17:19, 13 October 2024
cofactor SAM contains a rich number of pi bonds from phenylalanine and tyrosine residues in the active site help to keep it in its binding pocket through...
16 KB (1,894 words) - 10:01, 27 March 2024
Retrieved 2020-11-22. Wang, P. (2015). "Induction of human pancreatic beta cell replication by inhibitors of dual specificity tyrosine regulated kinase". Nature...
20 KB (2,016 words) - 19:39, 8 September 2024
PMID 29083801. Yourick JJ, Faiman MD (November 1987). "Diethyldithiocarbamic acid-methyl ester: a metabolite of disulfiram and its alcohol sensitizing properties...
32 KB (3,294 words) - 16:16, 23 September 2024
but its chemical similarity with d-amphetamine (in which a methyl group is substituted at the α-carbon) underlines the possibility that this molecule may...
37 KB (4,431 words) - 19:04, 30 September 2024
to serotonin Tryptophan to tryptamine Phenylalanine to phenethylamine L-Tyrosine to tyramine Centrally mediated side effects of higher levels of neuro-...
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inhibiting VMAT2. Dopamine precursors including L-phenylalanine and L-tyrosine are used as dietary supplements. L-DOPA (Levodopa), another precursor,...
23 KB (2,278 words) - 09:55, 28 September 2024
Genistein (section Tyrosine kinase inhibitor)
known activity of genistein is tyrosine kinase inhibitor, mostly of epidermal growth factor receptor (EGFR). Tyrosine kinases are less widespread than...
45 KB (4,451 words) - 16:57, 22 September 2024
Methamphetamine (redirect from Methyl-α-methyl-phenyl-ethyl-amine)
administration. Because of the high lipophilicity of methamphetamine due to its methyl group, it can readily move through the blood–brain barrier faster than other...
156 KB (15,356 words) - 20:21, 18 October 2024
amphetamine derivative. It is also known as (R)-(–)-N,α-dimethyl-N-(2-propynyl)phenethylamine, (R)-(–)-N-methyl-N-2-propynylamphetamine, or N-propargyl-L-methamphetamine...
208 KB (20,184 words) - 23:53, 18 October 2024
Para-Methoxy-N-methylamphetamine (redirect from Methyl-MA)
para-Methoxy-N-methylamphetamine (also known as PMMA, Red Mitsubishi), chemically known as methyl-MA, 4-methoxy-N-methylamphetamine, and 4-MMA (or 4-PMDA, as listed to its...
17 KB (1,428 words) - 07:17, 5 October 2024
(2001). Substance Abuse in the Mentally and Physically Disabled. CRC Press. p. 26. ISBN 978-0-8247-4497-7. Saran JS, Barbano RL, Schult R, Wiegand TJ, Selioutski...
69 KB (6,193 words) - 19:34, 26 September 2024
4-Methylpentedrone (redirect from 4-Methyl-α-methylamino-valerophenone)
4-Methylpentedrone (also known as 4-MPD and 4-Methyl-α-methylamino-valerophenone), is a stimulant drug of the cathinone class that has been sold online...
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Naoi M, Maruyama W, Shamoto-Nagai M, Riederer P (June 2024). "Toxic interactions between dopamine, α-synuclein, monoamine oxidase, and genes in mitochondria...
137 KB (13,992 words) - 23:53, 18 October 2024
PMID 3665338. S2CID 46130982. Guentert TW, Tucker G, Korn A, Pfefen JP, Haefelfinger P, Schoerlin MP (1990). "Pharmacokinetics of moclobemide after single and multiple...
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a 1,3-oxazolidin-2-one moiety with an aryl group at position 3 and an S-methyl group, with another substituent attached to it, at position 5 (the R-enantiomers...
108 KB (10,601 words) - 21:38, 19 October 2024
α-Pyrrolidinoisohexanophenone (mainly known as A-PiHP or α-PiHP) is a stimulant drug of the cathinone class that has been sold online as a designer drug...
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to phenethylamine – a trace amine which functions as a neuromodulator L-Tyrosine to tyramine – a trace amine neuromodulator L-Histidine to histamine – a...
17 KB (1,946 words) - 05:24, 16 September 2024