• Thumbnail for Α-Methyl-p-tyrosine
    α-Methyl-p-tyrosine (AMPT), or simply α-methyltyrosine, also known in its chiral 2-(S) form as metirosine, is a tyrosine hydroxylase enzyme inhibitor and...
    24 KB (2,255 words) - 12:06, 8 October 2024
  • Thumbnail for Α-Methyl-5-hydroxytryptophan
    α-Methyl-5-hydroxytryptophan (α-Me-5-HTP) is a synthetic tryptamine derivative, an artificial amino acid, and a prodrug of α-methylserotonin. It is the...
    10 KB (786 words) - 03:51, 14 October 2024
  • Thumbnail for Α-Methylphenylalanine
    (para-chlorophenylalanine) Metirosine (α-methyl-para-tyrosine) Methyldopa (α-methyl-DOPA) α-Methyltryptophan 3,4-Dihydroxystyrene "alpha-methyl-L-phenylalanine". PubChem...
    7 KB (504 words) - 15:00, 8 October 2024
  • Thumbnail for 9-Methyl-β-carboline
    9-Methyl-β-carboline (9-Me-BC) is a heterocyclic amine of the β-carboline family, and a research chemical. 9-Me-BC is a methylated derivative of β-carboline...
    7 KB (553 words) - 19:38, 8 September 2024
  • Thumbnail for Α-Methyltryptophan
    αMTP is a viable agent for such purposes. αMTP is first converted by tryptophan hydroxylase into α-methyl-5-hydroxytryptophan (αM-5-HTP or α-methyl-5-HTP)...
    12 KB (1,157 words) - 03:09, 14 October 2024
  • Thumbnail for Methylene blue
    it gets serially demethylated and forms all the tri-, di-, mono- and non-methyl intermediates, which are Azure B, Azure A, Azure C, and thionine, respectively...
    47 KB (5,008 words) - 19:20, 15 October 2024
  • Thumbnail for Catechol-O-methyltransferase
    neurotransmitters (dopamine, epinephrine, and norepinephrine). The enzyme introduces a methyl group to the catecholamine, which is donated by S-adenosyl methionine (SAM)...
    29 KB (3,236 words) - 00:14, 10 July 2024
  • Thumbnail for Tyrosine hydroxylase
    to tyrosine hydroxylase could be generated by the tyrosine hydroxylase system itself. Tyrosine hydroxylase can be inhibited by the drug α-methyl-para-tyrosine...
    37 KB (4,405 words) - 16:27, 9 October 2024
  • Thumbnail for List of dopaminergic drugs
    acid • Nepicastat • Phenopicolinic acid • Tropolone L-Phenylalanine → L-tyrosine → L-DOPA (levodopa) Ferrous iron (Fe2+) • Tetrahydrobiopterin • Vitamin...
    16 KB (845 words) - 15:11, 27 September 2024
  • Thumbnail for Harmala alkaloid
    7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole Harmine is a reversible inhibitor of monoamine oxidase A (RIMA). Harmaline: C13H14N2O 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3...
    14 KB (1,526 words) - 03:35, 8 September 2024
  • Thumbnail for Α-Methyltryptamine
    (5-MeO-αMT), α,N-dimethyltryptamine (α,N-DMT; N-methyl-αMT), α,N,N-trimethyltryptamine (α,N,N-TMT; N-dimethyl-αMT), α-methylserotonin (α-methyl-5-HT; 5-hydroxy-αMT)...
    40 KB (3,622 words) - 09:10, 9 October 2024
  • Thumbnail for Tobacco
    & Zhou 2004, p. 26. "Guindon & Boisclair" 2004, pp. 13–16. Samet & Yoon 2001, p. 5-6. Surgeon General's Report Women and Smoking 2001, p. 47. "WHO/WPRO-Tobacco"...
    103 KB (10,986 words) - 06:41, 16 September 2024
  • Thumbnail for Monoamine oxidase inhibitor
    Pharmacology from H.P. Rang, M.M. Dale, J.M. Ritter, P.K. Moore, year 2003, chapter 38 "MHRA PAR Dextromethorphan hydrobromide, p. 12" (PDF). Archived...
    37 KB (4,010 words) - 17:19, 13 October 2024
  • Thumbnail for Phenylethanolamine N-methyltransferase
    cofactor SAM contains a rich number of pi bonds from phenylalanine and tyrosine residues in the active site help to keep it in its binding pocket through...
    16 KB (1,894 words) - 10:01, 27 March 2024
  • Retrieved 2020-11-22. Wang, P. (2015). "Induction of human pancreatic beta cell replication by inhibitors of dual specificity tyrosine regulated kinase". Nature...
    20 KB (2,016 words) - 19:39, 8 September 2024
  • Thumbnail for Disulfiram
    PMID 29083801. Yourick JJ, Faiman MD (November 1987). "Diethyldithiocarbamic acid-methyl ester: a metabolite of disulfiram and its alcohol sensitizing properties...
    32 KB (3,294 words) - 16:16, 23 September 2024
  • Thumbnail for Monoamine oxidase B
    but its chemical similarity with d-amphetamine (in which a methyl group is substituted at the α-carbon) underlines the possibility that this molecule may...
    37 KB (4,431 words) - 19:04, 30 September 2024
  • Thumbnail for Benserazide
    to serotonin Tryptophan to tryptamine Phenylalanine to phenethylamine L-Tyrosine to tyramine Centrally mediated side effects of higher levels of neuro-...
    8 KB (460 words) - 06:40, 18 September 2024
  • Thumbnail for Dopaminergic
    inhibiting VMAT2. Dopamine precursors including L-phenylalanine and L-tyrosine are used as dietary supplements. L-DOPA (Levodopa), another precursor,...
    23 KB (2,278 words) - 09:55, 28 September 2024
  • Thumbnail for Genistein
    known activity of genistein is tyrosine kinase inhibitor, mostly of epidermal growth factor receptor (EGFR). Tyrosine kinases are less widespread than...
    45 KB (4,451 words) - 16:57, 22 September 2024
  • Thumbnail for Methamphetamine
    administration. Because of the high lipophilicity of methamphetamine due to its methyl group, it can readily move through the blood–brain barrier faster than other...
    156 KB (15,356 words) - 20:21, 18 October 2024
  • Thumbnail for Selegiline
    amphetamine derivative. It is also known as (R)-(–)-N,α-dimethyl-N-(2-propynyl)phenethylamine, (R)-(–)-N-methyl-N-2-propynylamphetamine, or N-propargyl-L-methamphetamine...
    208 KB (20,184 words) - 23:53, 18 October 2024
  • Thumbnail for Para-Methoxy-N-methylamphetamine
    para-Methoxy-N-methylamphetamine (also known as PMMA, Red Mitsubishi), chemically known as methyl-MA, 4-methoxy-N-methylamphetamine, and 4-MMA (or 4-PMDA, as listed to its...
    17 KB (1,428 words) - 07:17, 5 October 2024
  • Thumbnail for Diphenhydramine
    (2001). Substance Abuse in the Mentally and Physically Disabled. CRC Press. p. 26. ISBN 978-0-8247-4497-7. Saran JS, Barbano RL, Schult R, Wiegand TJ, Selioutski...
    69 KB (6,193 words) - 19:34, 26 September 2024
  • Thumbnail for 4-Methylpentedrone
    4-Methylpentedrone (also known as 4-MPD and 4-Methyl-α-methylamino-valerophenone), is a stimulant drug of the cathinone class that has been sold online...
    3 KB (202 words) - 08:09, 11 September 2024
  • Thumbnail for Pharmacology of selegiline
    Naoi M, Maruyama W, Shamoto-Nagai M, Riederer P (June 2024). "Toxic interactions between dopamine, α-synuclein, monoamine oxidase, and genes in mitochondria...
    137 KB (13,992 words) - 23:53, 18 October 2024
  • Thumbnail for Moclobemide
    PMID 3665338. S2CID 46130982. Guentert TW, Tucker G, Korn A, Pfefen JP, Haefelfinger P, Schoerlin MP (1990). "Pharmacokinetics of moclobemide after single and multiple...
    83 KB (9,143 words) - 12:35, 12 October 2024
  • Thumbnail for Linezolid
    a 1,3-oxazolidin-2-one moiety with an aryl group at position 3 and an S-methyl group, with another substituent attached to it, at position 5 (the R-enantiomers...
    108 KB (10,601 words) - 21:38, 19 October 2024
  • Thumbnail for Α-PHiP
    α-Pyrrolidinoisohexanophenone (mainly known as A-PiHP or α-PiHP) is a stimulant drug of the cathinone class that has been sold online as a designer drug...
    6 KB (412 words) - 13:48, 17 July 2024
  • Thumbnail for Aromatic L-amino acid decarboxylase
    to phenethylamine – a trace amine which functions as a neuromodulator L-Tyrosine to tyramine – a trace amine neuromodulator L-Histidine to histamine – a...
    17 KB (1,946 words) - 05:24, 16 September 2024