Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme (EC 6.4.1.2) that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA...
27 KB (2,990 words) - 21:27, 4 July 2024
Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism. Its main function...
22 KB (2,097 words) - 03:05, 2 November 2024
enzymology, a [acetyl-CoA carboxylase] kinase (EC 2.7.11.27) is an enzyme that catalyzes the chemical reaction ATP + [acetyl-CoA carboxylase] ⇌ {\displaystyle...
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The enzyme [acetyl-CoA carboxylase]-phosphatase (EC 3.1.3.44) catalyzes the reaction [acetyl-CoA carboxylase] phosphate + H2O ⇌ {\displaystyle \rightleftharpoons...
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Coenzyme A (redirect from CoA-SH)
pathways. Acetyl-CoA is utilised in the post-translational regulation and allosteric regulation of pyruvate dehydrogenase and carboxylase to maintain...
26 KB (2,528 words) - 21:25, 28 August 2024
transfer more acetyl-CoA out of the mitochondrion). The cytosolic acetyl-CoA is carboxylated by acetyl-CoA carboxylase into malonyl-CoA, the first committed...
50 KB (5,561 words) - 07:03, 13 August 2024
mitochondrion as malate. The cytosolic acetyl-CoA is carboxylated by acetyl-CoA carboxylase into malonyl-CoA, the first committed step in the synthesis...
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Phenoxy herbicide (redirect from Acetyl-CoA carboxylase inhibitor)
[sic] feature. This group of herbicides acts by inhibiting plant acetyl-CoA carboxylase (ACCase), a completely different mechanism of action to that of...
12 KB (1,263 words) - 13:36, 21 November 2024
lipogenesis, promotes fatty acid oxidation, switches off acetyl-CoA carboxylase, turns on malonyl-CoA decarboxylase, and consequently induces ketogenesis....
19 KB (2,337 words) - 16:33, 17 August 2024
Lipogenesis (section Acetyl-CoA carboxylase)
converts pyruvate into acetyl-CoA. Acetyl-CoA carboxylase (ACC), converts acetyl-CoA produced by PDH into malonyl-CoA. Malonyl-CoA provides the two-carbon...
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inactivates acetyl-CoA carboxylase, which creates malonyl-CoA from acetyl-CoA, through cAMP-dependent and/or cAMP-independent kinases. Malonyl-CoA is a product...
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enzyme acetyl-CoA carboxylase. One molecule of acetyl-CoA joins with a molecule of bicarbonate, requiring energy rendered from ATP. Malonyl-CoA is utilised...
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Biotin carboxylases are a conserved enzyme present within biotin-dependent carboxylase complexes such as acetyl-CoA carboxylase. How biotin carboxylase functions...
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term fatty acid synthesis regulation is dependent on the rate of acetyl-CoA carboxylase (ACC) synthesis, the rate-limiting enzyme and first enzyme of the...
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propionyl-CoA as well as acetyl-CoA. Propionyl-CoA is later converted into succinyl-CoA through biotin-dependant propionyl-CoA carboxylase (PCC) and b12-dependant...
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carboxylase enzymes: Acetyl-CoA carboxylase alpha (ACC1) Acetyl-CoA carboxylase beta (ACC2) Pyruvate carboxylase (PC) Methylcrotonyl-CoA carboxylase (MCC)...
48 KB (5,181 words) - 04:28, 2 November 2024
two enzymes: the Acetyl-CoA carboxylase catalyzes the carboxylation of the Acetyl-CoA to Malonyl-CoA and Propionyl-CoA carboxylase catalyses the carboxylation...
43 KB (3,852 words) - 14:24, 18 July 2024
into acetyl-CoA and carbon dioxide. It is involved in fatty acid biosynthesis. To some degree, it reverses the action of Acetyl-CoA carboxylase. MCD presents...
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Acetylcarnitine (redirect from Acetyl-L-carnitine)
derivative and is formed in the reaction: acetyl-CoA + carnitine ⇌ CoA + acetylcarnitine where the acetyl group displaces the hydrogen atom in the central...
16 KB (1,833 words) - 03:05, 2 November 2024
6.4 includes ligases used to form carbon-carbon bonds, such as acetyl-CoA carboxylase EC 6.5 includes ligases used to form phosphoric ester bonds, such...
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a biotin—[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15) is an enzyme that catalyzes the chemical reaction ATP + biotin + apo-[acetyl-CoA:carbon-dioxide...
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biotin-dependent carboxylases. The biotin carboxyl carrier protein is an Acetyl CoA subunit that allows for Acetyl CoA to be catalyzed and converted to malonyl-CoA. More...
10 KB (1,387 words) - 18:13, 20 July 2024
Carnitine (section Acetyl-CoA Stabilization)
phosphorylates acetyl-CoA carboxylase, which normally catalyzes malonyl-CoA synthesis. This phosphorylation inhibits acetyl-CoA carboxylase, which in turn...
33 KB (3,582 words) - 20:12, 9 November 2024
varying degrees of activation by acetyl-CoA, but vertebrate PC typically requires it for activity. Pyruvate carboxylase was first discovered in 1959 at...
25 KB (2,888 words) - 19:53, 15 November 2024
oxidation produces citrate which can be converted to malonyl-CoA by acetyl-CoA carboxylase. Malonyl-CoA inhibits the carnitine palmitoyltransferase (CPT) that...
12 KB (1,520 words) - 20:36, 31 August 2024
Acetyl-CoA carboxylase 1 also known as ACC-alpha or ACCa is an enzyme that in humans is encoded by the ACACA gene. Acetyl-CoA carboxylase (ACC) is a complex...
10 KB (1,218 words) - 19:49, 16 November 2024
namely acetyl-CoA carboxylase and fatty acid synthase. The enzyme acetyl CoA carboxylase is responsible for introducing a carboxyl group to acetyl CoA, rendering...
11 KB (1,283 words) - 08:07, 16 July 2024
Methylcrotonyl CoA carboxylase (EC 6.4.1.4, MCC) (3-methylcrotonyl CoA carboxylase, methylcrotonoyl-CoA carboxylase) is a biotin-requiring enzyme located...
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HMG-CoA reductase is phosphorylated and inactivated by an AMP-activated protein kinase, which also phosphorylates and inactivates acetyl-CoA carboxylase,...
34 KB (4,113 words) - 16:29, 29 July 2024
Acetyl-CoA carboxylase 2 also known as ACC-beta or ACC2 is an enzyme that in humans is encoded by the ACACB gene. Acetyl-CoA carboxylase (ACC) is a complex...
10 KB (1,341 words) - 12:30, 18 January 2024