Angiopoietin is part of a family of vascular growth factors that play a role in embryonic and postnatal angiogenesis. Angiopoietin signaling most directly...
18 KB (2,150 words) - 20:17, 15 March 2024
Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and...
13 KB (1,623 words) - 00:35, 14 December 2023
The angiopoietin receptors are receptors that bind angiopoietin. TIE-1 and TIE-2 comprise the cell-surface receptors that bind and are activated by the...
3 KB (224 words) - 18:20, 21 September 2023
ANGPTL3 (redirect from Angiopoietin-related protein 3)
Angiopoietin-like 3, also known as ANGPTL3, is a protein that in humans is encoded by the ANGPTL3 gene. The protein encoded by this gene is a member of...
11 KB (1,194 words) - 20:56, 8 April 2022
ANGPT2 (redirect from Angiopoietin 2)
remodeling; similar to angiopoietin-1 See Angiopoietin#Clinical relevance ANGPT2 has been shown to interact with TEK tyrosine kinase. Angiopoietin GRCh38: Ensembl...
9 KB (1,113 words) - 03:54, 1 January 2024
Schlemm's canal (section Angiopoietin deficiency)
reduction in intraocular pressure. In the combined absence of angiopoietin 1 and angiopoietin 2, Schlemm's canal and episcleral lymphatic vasculature completely...
11 KB (1,166 words) - 00:55, 13 July 2024
The Angiopoietin-like proteins are proteins structurally like the angiopoietins but which do not bind to the angiopoietin receptors. Also known as the...
1 KB (106 words) - 13:22, 22 July 2023
ANGPT4 (redirect from Angiopoietin 4)
Angiopoietin-4 is a protein that in humans is encoded by the ANGPT4 gene. Angiopoietins are proteins with important roles in vascular development and...
7 KB (679 words) - 12:06, 26 January 2024
antibody to target both vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang-2). By targeting these pathways, faricimab stabilizes blood vessels...
20 KB (1,543 words) - 06:38, 10 March 2024
Angiopoietin-like 4 is a protein that in humans is encoded by the ANGPTL4 gene. Alternatively spliced transcript variants encoded with different isoforms...
26 KB (3,023 words) - 01:09, 1 March 2024
Angiopoietin-1 receptor also known as CD202B (cluster of differentiation 202B) is a protein that in humans is encoded by the TEK gene. Also known as TIE2...
14 KB (1,695 words) - 03:57, 23 December 2023
Angiopoietin-related protein 1 also known as angiopoietin-3 (ANG-3) is a protein that in humans is encoded by the ANGPTL1 gene. Angiopoietins are members...
5 KB (686 words) - 14:15, 25 January 2024
Angiopoietin-related protein 7 is a protein that in humans is encoded by the ANGPTL7 gene. It is one of the 8 angiopoietin-like proteins. Rare protein-altering...
4 KB (476 words) - 23:26, 5 January 2024
Angiopoietin-related protein 2 also known as angiopoietin-like protein 2 is a protein that in humans is encoded by the ANGPTL2 gene. Angiopoietin-like...
3 KB (431 words) - 09:01, 8 February 2023
pathway leading to angiogenesis.[clarification needed] The expression of angiopoietin-2 in the absence of VEGF leads to endothelial cell death and vascular...
40 KB (4,580 words) - 05:24, 3 June 2024
GalNAc conjugated small interfering RNA (siRNA) therapy, that targets angiopoietin-like 3. It is developed by Eli Lilly and Company to reduce the level...
5 KB (293 words) - 01:44, 9 May 2024
inhibitor levels) is associated with mutations in genes for Factor XII, angiopoietin 1, plasminogen or kininogen 1. The pathophysiologic mechanisms contributing...
41 KB (4,418 words) - 18:54, 20 July 2024
are many families, some of which are listed below: Adrenomedullin (AM) Angiopoietin (Ang) Autocrine motility factor Bone morphogenetic proteins (BMPs) Ciliary...
10 KB (1,131 words) - 19:14, 31 March 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
34 KB (3,021 words) - 04:42, 11 July 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
150 KB (15,741 words) - 10:54, 25 July 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
10 KB (579 words) - 06:46, 26 June 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
24 KB (2,877 words) - 10:08, 2 June 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
27 KB (2,608 words) - 12:02, 19 July 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
63 KB (7,427 words) - 14:51, 9 July 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
31 KB (3,413 words) - 23:30, 21 June 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
5 KB (412 words) - 23:17, 19 June 2023
Hedgehog pathway leads to an increase in Angiogenic Factors (angiopoietin-1 and angiopoietin-2), Cyclins (cyclin D1 and B1), anti-apoptotic genes and a...
59 KB (6,895 words) - 22:30, 25 April 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
108 KB (12,653 words) - 16:16, 10 July 2024
by endothelial cells. This is important for pericyte differentiation. Angiopoietin 1 and Tie-2 signaling is essential for maturation and stabilization of...
40 KB (4,640 words) - 22:39, 19 July 2024
factor receptor modulators Angiopoietin Agonists: Angiopoietin 1 Angiopoietin 4 Antagonists: Angiopoietin 2 Angiopoietin 3 Kinase inhibitors: Altiratinib...
92 KB (8,667 words) - 10:57, 23 July 2024