• Autolysins are endogenous lytic enzymes that break down the peptidoglycan components of biological cells which enables the separation of daughter cells...
    12 KB (1,393 words) - 23:33, 13 August 2023
  • pore-forming protein that can cause lysis of host cells and activate complement Autolysin (LytA)—activation of this protein lyses the bacteria releasing its internal...
    20 KB (2,313 words) - 22:53, 2 October 2024
  • Thumbnail for Staphylococcus aureus
    fission. Complete separation of the daughter cells is mediated by S. aureus autolysin, and in its absence or targeted inhibition, the daughter cells remain...
    114 KB (12,720 words) - 11:18, 29 October 2024
  • Thumbnail for Staphylococcus epidermidis
    Yang L, Zhu Y, Tolker-Nielsen T, Molin S, et al. (July 2007). "Role of autolysin-mediated DNA release in biofilm formation of Staphylococcus epidermidis"...
    28 KB (2,880 words) - 10:58, 11 August 2024
  • Thumbnail for Penicillin
    precursors triggers the activation of bacterial cell wall hydrolases and autolysins, which further digest the cell wall's peptidoglycans. The small size of...
    98 KB (10,637 words) - 21:20, 30 September 2024
  • The reaction probably catalyzed is: small molecules + autolysin (in) → small molecules + autolysin (out) Holin Lysin Transporter Classification Database...
    3 KB (384 words) - 18:59, 10 December 2023
  • lysis, such as: Most commonly, phage lysins, also known as endolysins Autolysin Cytolysin Egg lysin Hemolysin NK-lysin Streptolysin Cell lysis Toxin This...
    321 bytes (72 words) - 23:52, 19 September 2016
  • autolysis system. The reaction probably catalyzed by Hol is: Autolysin (Lys)in → Autolysin (Lys)out. Holin Lysin Holin Superfamily III Transporter Classification...
    3 KB (348 words) - 17:35, 31 December 2020
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    acids also assist in regulation of cell growth by limiting the ability of autolysins to break the β(1-4) bond between the N-acetyl glucosamine and the N-acetylmuramic...
    10 KB (1,206 words) - 03:28, 11 December 2023
  • Xylella fastidiosa strains. The reaction catalyzed by P35 holin is: autolysin (in) → autolysin (out) Bacteriophage Phage typing Holin Lysin Transporter Classification...
    2 KB (313 words) - 20:29, 25 May 2020
  • Thumbnail for Glycopeptide antibiotic
    structurally and ancestrally related to vancomycin, but they work by inhibiting autolysins through binding to peptidoglycan, therefore preventing cell division,...
    9 KB (1,032 words) - 18:32, 20 October 2024
  • Thumbnail for LysM domain
    design of the Enterococcus hirae muramidase-2 and Streptococcus faecalis autolysin". FEMS Microbiology Letters. 70 (3): 257–64. doi:10.1016/0378-1097(92)90707-u...
    3 KB (347 words) - 18:20, 6 October 2024
  • Thumbnail for Autophagy
    autophagy targeting proteins. And the specialized virulence factors such as autolysins, and iron sequestering proteins are potentially recognized uniquely by...
    77 KB (9,111 words) - 09:15, 16 October 2024
  • binding domain from a bacteriophage lysin, or the binding domain from an autolysin or bacteriocin, all of which bind to bacterial cell wall carbohydrate...
    3 KB (400 words) - 15:52, 12 March 2024
  • Thumbnail for Cefotaxime
    eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) in the absence of cell wall assembly. Due to the...
    18 KB (1,677 words) - 21:18, 19 October 2024
  • Thumbnail for Antimicrobial peptides
    wall synthesis, alteration of the cytoplasmic membrane, activation of autolysin, inhibition of DNA, RNA, and protein synthesis, and inhibition of certain...
    61 KB (6,549 words) - 03:13, 28 September 2024
  • Thumbnail for Piperacillin
    other substrates from binding. Moreover, this leads to the release of autolysins that break down the bacteria's cell wall. Some β-lactamase enzymes also...
    44 KB (4,767 words) - 05:13, 3 June 2024
  • Sthanam V. L.; Schneewind, Olaf (2013-10-11). "Secreted proteases control autolysin-mediated biofilm growth of Staphylococcus aureus". The Journal of Biological...
    8 KB (815 words) - 16:22, 3 December 2023
  • Thumbnail for Lysin
    membrane proteins that activate the host's autolytic mechanisms such as autolysins. Lysins were first used therapeutically in 2001 by the Fischetti lab (see...
    16 KB (1,989 words) - 07:05, 27 July 2024
  • weakened from the absence of cross-linkages. The continued activity of autolysins, that function like lysozymes and cleave glycosidic and peptide bonds...
    69 KB (8,479 words) - 19:42, 20 October 2024
  • Thumbnail for CHAP domain
    trypanosomal glutathionylspermidine amidases. A variety of bacterial autolysins. A Nocardia aerocolonigenes putative esterase. Streptococcus pneumoniae...
    3 KB (320 words) - 03:59, 30 December 2021
  • Thumbnail for Glutamyl endopeptidase GluV8
    Narayana SV, Schneewind O (October 2013). "Secreted proteases control autolysin-mediated biofilm growth of Staphylococcus aureus". The Journal of Biological...
    14 KB (1,503 words) - 06:40, 19 August 2023
  • functional in gram-negative bacteria: triggering of the major pneumococcal autolysin in Escherichia coli". Molecular Microbiology. 19 (4): 667–681. doi:10...
    7 KB (723 words) - 07:28, 31 July 2021
  • protein with 4 putative TMSs, is believed to be the holin which exports the autolysin CidB, while LrgA may be an anti-holin, a protein that binds and inhibits...
    8 KB (986 words) - 06:34, 29 November 2023
  • Thumbnail for Corticovirus
    of phage-encoded proteins P17 and P18 as well as an unidentified host autolysin. However, identification of PM2-like proviruses in bacterial genomes indicates...
    7 KB (766 words) - 21:56, 28 November 2023
  • PUTS BEBEE OUT OF CORNELL; College Objects to Doctor's Exploitation of Autolysin and Ends His Department. Triolo, Victor A. and Riegel, Ilse L. (1961)...
    4 KB (553 words) - 14:15, 30 July 2024
  • Thumbnail for ACES (buffer)
    of ACES has been published in a protocol for the analysis of bacterial autolysins in a discontinuous SDS-PAGE system. Potential inhibition of ACES and other...
    3 KB (262 words) - 15:05, 9 September 2023
  • Thumbnail for Peptidoglycan binding domain
    cwlA precursor (cell wall hydrolase, autolysin, EC 3.5.1.28) Autolytic lysozyme (1,4-beta-N-acetylmuramidase, autolysin, EC 3.2.1.17) Membrane-bound lytic...
    6 KB (674 words) - 15:13, 1 October 2024
  • Thumbnail for N-acetylmuramoyl-L-alanine amidase
    peptidoglycan biosynthesis. Autolysins and some phage lysins are examples of N-acetylmuramoyl-L-alanine amidases. Phage lysins Autolysins PGLYRP2 Campbell JN;...
    4 KB (307 words) - 15:04, 22 September 2024
  • coli. Thus, it appears that holins can export various toxins as well as autolysins. The holes caused by S105 have an average diameter of 340 nm, and some...
    12 KB (1,531 words) - 03:25, 12 February 2024