Bone marrow failure occurs in individuals who produce an insufficient amount of red blood cells, white blood cells or platelets. Red blood cells transport...

study of this and other bone marrow failure syndromes has improved scientific understanding of the mechanisms of normal bone marrow function and development...

crisis. If pancytopenia is present, bone marrow failure must be considered and evaluation for bone marrow failure syndromes or aplastic anemia must be...

cancer and various cancer syndromes. Blood cells are produced in the bone marrow by stem cells that reside there. Aplastic anemia causes a deficiency...

amegakaryocytic thrombocytopenia (CAMT) is a rare autosomal recessive bone marrow failure syndrome characterized by severe thrombocytopenia, which can progress...

Bone marrow adipose tissue (BMAT), sometimes referred to as marrow adipose tissue (MAT), is a type of fat deposit in bone marrow. It increases in states...

myelofibrosis have an increased risk of acute meyloid leukemia and frank bone marrow failure. In 2016, prefibrotic primary myelofibrosis was formally classified...

(MDS) is one of a group of cancers in which immature blood cells in the bone marrow do not mature, and as a result, do not develop into healthy blood cells...

improves some cases of severe, infantile osteopetrosis associated with bone marrow failure, and offers the best chance of longer-term survival for individuals...

congenital disorder characterized by exocrine pancreatic insufficiency, bone marrow dysfunction, skeletal and cardiac abnormalities and short stature. After...

or racemosa), various cytopenias, stroke, immunodeficiency, and bone marrow failure. Symptoms often onset during early childhood, but some cases have...

that platelets transfusions are given to people with reversible bone marrow failure to reduce the risk of spontaneous bleeding when the platelet count...

prevention of graft-vs.-host disease, and conditions involving bone marrow failure, including aplastic anemia and has additional off-label uses. Antithymocyte...

progressive bone marrow failure, and intrauterine growth restriction. The primary cause of death in Hoyeraal–Hreidasson syndrome is bone marrow failure, but...

aplastic anemia. It is also the most common cause of hereditary bone marrow failure and may present with this disorder. GATA 2 deficiency has been diagnosed...

mainly affects the skin, but a major consequence is progressive bone marrow failure which occurs in over 80%, causing early mortality. DKC can be characterized...

dominant on the TERT and TERC loci. Patients with DC have severe bone marrow failure manifesting as abnormal skin pigmentation, leucoplakia (a white thickening...

telomere shortening, reduced hematopoietic stem cell function, and bone marrow failure. He later found that telomerase mutations also are a risk factor...

Inadequate or ineffective formation of granulocytes. This can be due to bone marrow failure associated with aplastic anemia, leukemia, or chemotherapeutic agents...

According to Cortázar's biographer Miguel Herráez, Dunlop died of "bone marrow failure" ("aplasia medular") and Cortázar of leukemia. Testimonies given...

medication which is used mainly in the treatment of anemia due to bone marrow failure. It is given by injection into muscle. Although it was widely used...

production index, normal MCV and hemolysis or loss may be seen in bone marrow failure or anemia of chronic disease, with superimposed or related hemolysis...

outside the bone marrow, within the spleen or liver. This is termed extramedullary erythropoiesis. The bone marrow of essentially all the bones produces...

syndromes (MDS) Congenital dyserythropoietic anemia Aplastic anemia and bone marrow failure syndromes Inherited disorders of DNA synthesis Homocystinuria Lesch-Nyhan...

type Bone fragility craniosynostosis proptosis hydrocephalus Bone marrow failure neurologic abnormalities Bone marrow failure Bone neoplasms Bone tumor...

and overly thick blood. The plasma cells can also form a mass in the bone marrow or soft tissue. When one tumor is present, it is called a plasmacytoma;...

neutropenia are Shwachman–Diamond syndrome, Cyclic neutropenia, bone marrow failure syndromes, cartilage–hair hypoplasia, reticular dysgenesis, and Barth...

"Function and Malfunction of Hematopoietic Stem Cells in Primary Bone Marrow Failure Syndromes". Current Stem Cell Research & Therapy. 2 (1): 39–52. doi:10...

pediatric hematologist/oncologist and physician-scientist who researches bone marrow failure syndromes. She is a staff clinician in the clinical genetics branch...

Metenolone esters are used mainly in the treatment of anemia due to bone marrow failure. Metenolone acetate is taken by mouth, while metenolone enanthate...