Brigatinib, sold under the brand name Alunbrig among others, is a small-molecule targeted cancer therapy being developed by Ariad Pharmaceuticals, Inc...
10 KB (796 words) - 12:29, 5 August 2024
ARIAD Pharmaceuticals (section Brigatinib (Alunbrig))
resistant to or unable to tolerate other tyrosine kinase inhibitors, and brigatinib, a lung cancer drug which has completed its registration trial in ALK...
16 KB (1,353 words) - 20:55, 16 October 2024
osimertinib, crizotinib, daclatasvir, sofosbuvir, afatinib, axitinib, brigatinib, baricitinib, cabozantinib, dasatinib, neratinib, eltrombopag, ibrutinib...
5 KB (232 words) - 10:23, 8 March 2024
phase 3 ALEX trial comparing it with crizotinib. Ariad's and Takeda's brigatinib (also an inhibitor of mutated EGFR) was the latest second-generation inhibitor...
17 KB (1,951 words) - 10:39, 25 January 2024
"EGFR inhibitors", EGFRi), including gefitinib, erlotinib, afatinib, brigatinib and icotinib for lung cancer, and cetuximab for colon cancer. More recently...
60 KB (6,879 words) - 14:26, 16 July 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
121 KB (13,799 words) - 18:53, 22 October 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
93 KB (8,729 words) - 06:34, 10 November 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
149 KB (15,703 words) - 16:01, 5 November 2024
treated with ALK inhibitors crizotinib, or its successors alectinib, brigatinib, and ceritinib. Those treated with ALK inhibitors who relapse can then...
90 KB (9,784 words) - 07:53, 10 October 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
69 KB (6,089 words) - 12:41, 9 November 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
31 KB (3,421 words) - 06:52, 2 November 2024
Encorafenib L01ED01 Crizotinib L01ED02 Ceritinib L01ED03 Alectinib L01ED04 Brigatinib L01ED05 Lorlatinib L01EE01 Trametinib L01EE02 Cobimetinib L01EE03 Binimetinib...
12 KB (877 words) - 15:36, 25 January 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
34 KB (3,021 words) - 12:39, 5 August 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
13 KB (1,177 words) - 01:44, 4 November 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
5 KB (412 words) - 23:17, 19 June 2023
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
21 KB (1,815 words) - 18:49, 29 October 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
43 KB (4,651 words) - 13:41, 27 July 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
10 KB (1,179 words) - 18:31, 8 August 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
73 KB (6,455 words) - 04:22, 2 November 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
24 KB (2,872 words) - 06:27, 22 July 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
71 KB (6,702 words) - 05:32, 9 August 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
46 KB (5,344 words) - 17:28, 12 October 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
16 KB (1,784 words) - 04:08, 6 January 2024
Receptor tyrosine kinase ErbB: HER1/EGFR (Afatinib Aumolertinib Brigatinib Dacomitinib Erlotinib Gefitinib Icotinib Lazertinib Mobocertinib Olmutinib Osimertinib...
12 KB (821 words) - 02:57, 12 October 2024
Midostaurin Novartis Pharmaceuticals FLT3-positive acute myeloid leukemia Brigatinib Takeda Pharmaceuticals ALK-positive non-small cell lung cancer Durvalumab...
34 KB (180 words) - 17:05, 14 October 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
25 KB (2,086 words) - 02:24, 16 July 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
22 KB (1,994 words) - 08:45, 4 November 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
24 KB (1,710 words) - 19:18, 30 August 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
14 KB (1,689 words) - 01:31, 19 August 2024
Transforming growth factor alpha (TGFα) Kinase inhibitors: Afatinib Agerafenib Brigatinib Canertinib Dacomitinib Erlotinib Gefitinib Grandinin Icotinib Lapatinib...
42 KB (3,935 words) - 20:28, 27 October 2024