cathepsin B, cathepsin C, cathepsin F, cathepsin H, cathepsin K, cathepsin L, cathepsin L2 or V, cathepsin O, cathepsin S, cathepsin Z, and cathepsin...
15 KB (1,787 words) - 22:29, 25 April 2024
Cathepsin L2 (or V) (cysteine protease) Cathepsin O (cysteine protease) Cathepsin S (cysteine protease) Cathepsin W (cysteine proteinase) Cathepsin Z...
20 KB (2,372 words) - 09:11, 4 July 2024
Cathepsin B belongs to a family of lysosomal cysteine proteases known as the cysteine cathepsins and plays an important role in intracellular proteolysis...
12 KB (1,346 words) - 00:48, 3 December 2023
Cathepsin X (EC 3.4.18.1, cathepsin B2, cysteine-type carboxypeptidase, cathepsin IV, cathepsin Z, acid carboxypeptidase, lysosomal carboxypeptidase B)...
3 KB (321 words) - 13:27, 26 August 2023
Cathepsin G is a protein that in humans is encoded by the CTSG gene. It is one of the three serine proteases of the chymotrypsin family that are stored...
24 KB (2,860 words) - 07:04, 3 January 2024
Osteoclast (section Cathepsin K and other cathepsins)
cathepsin K. Studies on cathepsin L knockout mice have been mixed, with a report of reduced trabecular bone in homozygous and heterozygous cathepsin L...
26 KB (2,918 words) - 00:49, 26 August 2024
Cathepsin L2 (EC 3.4.22.43, also known as cathepsin V or cathepsin U) is a protein encoded in humans by the CTSV gene. The protein is a human cysteine...
9 KB (1,018 words) - 16:54, 20 October 2024
Cathepsin F is a protein that in humans is encoded by the CTSF gene. Cysteine cathepsins are a family of cysteine proteases that represent a major component...
8 KB (994 words) - 22:02, 2 October 2024
NF-κB pathways. Lawrence CP, et al. (15 September 2006). "The cathepsin B inhibitor, Z-FA-FMK, inhibits human T cell proliferation in vitro and modulates...
2 KB (123 words) - 23:10, 9 May 2022
Cathepsin W is a protein that in humans is encoded by the CTSW gene. The protein encoded by this gene, a member of the peptidase C1 family of cysteine...
5 KB (667 words) - 20:35, 2 October 2024
Papain-like protease (redirect from Cysteine cathepsin)
all domains of life. In animals, the group is often known as cysteine cathepsins or, in older literature, lysosomal peptidases. In the MEROPS protease...
22 KB (2,191 words) - 02:20, 23 October 2024
Mirković B, Renko M, Turk S, Sosič I, Jevnikar Z, Obermajer N, et al. (August 2011). "Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and...
10 KB (1,079 words) - 14:07, 26 September 2024
since cathepsin L is a necessary factor for SARS-CoV-2 cell entry. Ou X, Liu Y, Lei X, Li P, Mi D, Ren L, Guo L, Guo R, Chen T, Hu J, Xiang Z, Mu Z, Chen...
8 KB (812 words) - 08:01, 4 August 2024
to other cytotoxic immune serine proteases, such as the granzymes and cathepsin G. It is more distantly related to the digestive CELA1. The neutrophil...
9 KB (1,111 words) - 20:35, 7 May 2024
by cathepsins (primarily cathepsin L) in endolysosomes. Hydroxychloroquine inhibits the action of cathepsin L in endolysosomes, but because cathepsin L...
37 KB (4,726 words) - 03:37, 30 September 2024
monoclonal antibody is stable in extracellular fluid, but is cleaved by cathepsin once the conjugate has entered a tumor cell, thus activating the antimitotic...
9 KB (649 words) - 22:01, 12 August 2023
metabolism of some drugs in the body. It is also an inhibitor of human cathepsin B. Amentoflavone has a variety of in vitro activities including antimalarial...
7 KB (509 words) - 05:04, 19 December 2023
host cell. The virion escapes when the pH of the endosome drops or when cathepsin, a host cysteine protease, cleaves it. The virion then releases RNA into...
122 KB (12,462 words) - 03:40, 15 August 2024
ability to produce future virions. Olgotrelvir also appears to inhibit cathepsin L (CTSL), a protein implicated in facilitating viral entry of SARS-CoV-2...
10 KB (800 words) - 14:27, 31 October 2024
Gaucher disease. These markers include angiotensin-converting enzyme, cathepsin S, chitotriosidase, and CCL18 in the blood plasma; and tumor necrosis...
30 KB (3,308 words) - 04:25, 22 November 2024
and defensins that are used to kill bacteria, proteolytic enzymes and cathepsin G to break down (bacterial) proteins, lysozyme to break down bacterial...
23 KB (2,454 words) - 19:23, 29 October 2024
IRL Press at Oxford University Press, Oxford. Chromatin, Histones & Cathepsin; PMAP The Proteolysis Map-animation Nature journal: recent chromatin publications...
53 KB (5,924 words) - 18:51, 18 September 2024
or TNF receptor) was stable in extracellular fluid. It is cleavable by cathepsin and safe for therapy. Trastuzumab emtansine is a combination of the...
41 KB (4,305 words) - 11:56, 24 August 2024
NETs contain proteins from azurophilic granules (neutrophil elastase, cathepsin G and myeloperoxidase), specific granules (lactoferrin), tertiary granules...
29 KB (3,352 words) - 06:33, 19 October 2024
PMC 2763347. PMID 19876394. Clark SR, Ma AC, Tavener SA, McDonald B, Goodarzi Z, Kelly MM, et al. (April 2007). "Platelet TLR4 activates neutrophil extracellular...
54 KB (5,770 words) - 22:58, 3 November 2024
process, with additional contributions from cysteine proteases cathepsin B and cathepsin L in endosomes. Trypsin and trypsin-like proteases have also been...
75 KB (7,399 words) - 06:53, 9 November 2024
Wiktionary, the free dictionary. HistoneDB 2.0 - Database of histones and variants at NCBI Chromatin, Histones & Cathepsin; PMAP The Proteolysis Map-animation...
84 KB (9,582 words) - 18:07, 20 August 2024
by cathepsins (primarily cathepsin L) in endolysosomes. Hydroxychloroquine inhibits the action of cathepsin L in endolysosomes, but because cathepsin L...
48 KB (5,825 words) - 03:28, 4 November 2024
protein is then activated by the host's pH-dependent cysteine protease cathepsin L. Activation of the receptor-attached spike protein causes a conformational...
52 KB (5,899 words) - 06:01, 22 August 2024
degradation by import of enzymes with specificity for different substrates; cathepsins are the major class of hydrolytic enzymes, while lysosomal alpha-glucosidase...
43 KB (4,709 words) - 13:50, 12 October 2024