Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic (also called second-generation...

Clozapine N-oxide (CNO) is a synthetic drug used mainly in biomedical research as a ligand to activate Designer Receptors Exclusively Activated by Designer...

antipsychotics, known as atypical antipsychotics, arrived with the introduction of clozapine in the early 1970s followed by others (e.g., risperidone). Both generations...

risperidone and olanzapine; and produce weight gain similar to risperidone, clozapine and aripiprazole. They concluded that it produces suicide attempt, suicide;...

a major active metabolite of the atypical antipsychotic drug clozapine. Unlike clozapine, it possesses intrinsic activity at the D2/D3 receptors, and...

member of the dibenzoxazepine class and structurally very similar to clozapine. Several researchers have argued that loxapine, initially classified as...

DHA-clozapine (tentative trade name Clozaprexin) is an atypical antipsychotic drug candidate that was created and originally tested by chemists at Protarga...

quit before the 6-week completion date. Treatment with olanzapine (like clozapine) may result in increased weight gain and increased glucose and cholesterol...

cases of bowel obstruction or constipation (such as those related to clozapine treatment) fecal vomiting has been identified as a cause of death. Fecal...

Medications that can cause overproduction of saliva include: aripiprazole clozapine pilocarpine ketamine potassium chlorate risperidone pyridostigmine Substances...

antipsychotics, in which case clozapine is offered. In a network comparative meta-analysis of 15 antipsychotic drugs, clozapine was significantly more effective...

weeks to two of three different antipsychotics) in the remaining 20%. Clozapine is considered a first choice treatment for treatment resistant schizophrenia...

and mirtazapine, and some antipsychotics. The atypical antipsychotic clozapine in particular is largely restricted to treatment-resistant cases and mandatory...

vestibular branches of the eighth cranial nerve and to the renal tubules. Clozapine and latrepirdine are examples of drugs used in the treatment of CNS disorders...

receptors (GPCR) engineered to respond exclusively to synthetic ligands, like clozapine N-oxide (CNO), and not to endogenous ligands. Several types of these receptors...

Examples of common anticholinergics: Antimuscarinic agents Antipsychotics (clozapine, quetiapine) Atropine Benztropine Biperiden Chlorpheniramine Certain SSRIs...

antipsychotics (e.g., aripiprazole, asenapine, brexpiprazole, cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone...

lauroxil Brilaroxazine† Brexpiprazole Cariprazine Tricyclics: Asenapine Clozapine# Olanzapine (+samidorphan) Quetiapine Zotepine Others: Blonanserin Pimavanserin...

possible (although this may temporarily worsen symptoms) or switching to clozapine. Other medications such as valbenazine, tetrabenazine, or botulinum toxin...

complications of the use of a number of different antipsychotics (most notably clozapine) which involves abnormalities in the composition of a person's blood (e...

the effectiveness of clozapine in treating suicide attempts in patients with schizophrenia, which led to FDA approval of clozapine for treating suicide...

Zuclopenthixol Atypical antipsychotics: Asenapine Clorotepine Clotiapine Clozapine DHA-clozapine Fluperlapine Iloperidone Norclozapine Norquetiapine Olanzapine...

antipsychotics (e.g., aripiprazole, asenapine, brexpiprazole, cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone...

further understanding of the use of clozapine. In 2022 he suggested a refined phenotype for genetic studies into clozapine-related agranulocytosis. He has...

(piperazine attached via side chain) Amoxapine Clopenthixol Clorotepine Clozapine Cyanothepin Doclothepin Docloxythepin Flupentixol Fluphenazine Isofloxythepin...

with similar pharmacology and effects to the structurally related drug clozapine. It has two enantiomers, but has only been studied as the racemic mix...

physical forms for clozapine as compared to 60 distinct physical forms for olanzapine. The experimental screening results of clozapine are consistent with...

Anisodamine Anisodine Atiprosin Atypical antipsychotics (e.g., brexpiprazole, clozapine, olanzapine, quetiapine, risperidone) Benoxathian Beta blockers (e.g....

Tourette's syndrome), and atypical antipsychotics like risperidone and clozapine. Non-pharmacologic treatments that have shown some degree of efficacy...

rectifying potassium channel-specific: Barium Caramiphen Cloperastine Clozapine Dextromethorphan Ethosuximide Ifenprodil Tertiapin Tipepidine Activators...