• Thumbnail for Complement membrane attack complex
    The membrane attack complex (MAC) or terminal complement complex (TCC) is a complex of proteins typically formed on the surface of pathogen cell membranes...
    9 KB (1,061 words) - 05:28, 8 January 2024
  • Thumbnail for Complement system
    cell-killing membrane attack complex. About 50 proteins and protein fragments make up the complement system, including plasma proteins, and cell membrane receptors...
    41 KB (5,016 words) - 12:33, 9 September 2024
  • Thumbnail for Complement component 5
    the complement membrane attack complex. Deficiency is thought to cause Leiner's disease. Complement component 5 is the fifth component of complement, which...
    9 KB (1,114 words) - 05:29, 8 January 2024
  • Thumbnail for CD59
    forming the complement membrane attack complex. It may also signal the cell to perform active measures such as endocytosis of the CD59-C9 complex. Endocytosis...
    14 KB (1,649 words) - 07:34, 23 August 2024
  • Thumbnail for Complement component 9
    cell membranes, causing lysis and cell death. C9 is one member of the complement membrane attack complex (MAC), which also includes complement components...
    7 KB (789 words) - 09:32, 27 February 2024
  • Thumbnail for Classical complement pathway
    terminal phase of the complement system, leading to the assembly of the membrane attack complex (MAC). The membrane attack complex creates a pore on the...
    16 KB (1,877 words) - 03:44, 5 April 2024
  • Thumbnail for Terminal complement pathway deficiency
    Terminal complement pathway deficiency is a genetic condition affecting the complement membrane attack complex (MAC). It involves deficiencies of C5,...
    3 KB (246 words) - 19:25, 6 November 2023
  • Thumbnail for C8 complex
    Complement component 8 is a protein involved in the complement system. It is part of the membrane attack complex (MAC). A hereditary deficiency of C8 can...
    2 KB (128 words) - 04:29, 14 March 2022
  • classical complement pathway is triggered by bonding protein C1q to these antibodies, resulting in formation of a membrane attack complex (MAC) and target...
    8 KB (957 words) - 17:30, 28 April 2024
  • Thumbnail for Alternative complement pathway
    membrane attack complex. Since C3b is free and abundant in the plasma, it can bind to either a host cell or a pathogen surface. To prevent complement...
    7 KB (865 words) - 13:08, 7 September 2024
  • Thumbnail for Perforin-1
    been shown to interact with calreticulin. Granzymes Defensin Complement membrane attack complex GRCh38: Ensembl release 89: ENSG00000180644 – Ensembl, May...
    16 KB (1,990 words) - 11:22, 29 June 2024
  • Thumbnail for C3-convertase
    to form the trimolecular C5 convertase to activate C5 for the membrane attack complex. C3 convertase formation can occur in three different pathways:...
    10 KB (1,319 words) - 09:52, 27 February 2024
  • Thumbnail for Complement component 6
    in the complement system. It is part of the membrane attack complex which can insert into the cell membrane and cause the cell to lyse. People with C6...
    7 KB (910 words) - 05:30, 8 January 2024
  • Thumbnail for Complement component 7
    Complement component 7 is a protein involved in the complement system of the innate immune system. C7 is part of the membrane attack complex (MAC) which...
    861 bytes (162 words) - 05:30, 8 January 2024
  • Thumbnail for Melioidosis
    the complement system and coagulation cascade, however the thick bacterial capsule prevent the action of the complement membrane attack complex. Additional...
    100 KB (11,505 words) - 13:29, 18 August 2024
  • antibody-antigen (Ab-Ag) complexes to the other effector proteins of the innate immune response. For example, the severity of a dysfunctional complement system can...
    35 KB (4,189 words) - 16:19, 7 November 2023
  • Thumbnail for Index of biochemistry articles
    competitive inhibition - complement 3A - complement 5A - complement factor B - complement membrane attack complex - complement receptor - complex - computational...
    29 KB (2,471 words) - 04:50, 19 January 2024
  • convertase is synthesized, complements are cleaved into subunits which either form a structure called the membrane attack complex (MAC) on the bacterial cell...
    17 KB (1,673 words) - 14:02, 19 July 2024
  • Thumbnail for Complement component 5a
    coordinates several basic defense mechanisms, including formation of the membrane attack complex (MAC), one of the most basic weapons of the innate immune system...
    15 KB (1,654 words) - 09:16, 27 February 2024
  • the complement system, CD59 for example blocks oligomerization of the complement peptide C9 stalling the formation of the Membrane Attack Complex (MAC)...
    16 KB (1,942 words) - 09:32, 27 February 2024
  • system Complement system Classical complement pathway Mannan-binding lectin pathway Alternate complement pathway Complement membrane attack complex Surface...
    38 KB (2,656 words) - 12:11, 30 October 2023
  • Thumbnail for Paroxysmal nocturnal hemoglobinuria
    microorganisms by opsonization to direct destabilization by the membrane attack complex. The main proteins that protect blood cells from destruction are...
    21 KB (4,077 words) - 06:39, 25 June 2024
  • Thumbnail for Decay-accelerating factor
    amplification convertases of the complement cascade, DAF indirectly blocks the formation of the membrane attack complex. This glycoprotein is broadly distributed...
    8 KB (962 words) - 14:13, 29 January 2023
  • the complement cascade. In the formation of the membrane attack complex, several complement proteins are inserted into the red blood cell membrane, forming...
    35 KB (3,442 words) - 17:09, 20 July 2024
  • Thumbnail for Complement component 3
    Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...
    13 KB (1,556 words) - 13:28, 23 September 2024
  • MACPF (category Membrane proteins)
    is named after a domain that is common to the membrane attack complex (MAC) proteins of the complement system (C6, C7, C8α, C8β and C9) and perforin (PF)...
    21 KB (2,334 words) - 06:15, 27 May 2024
  • expressed on the cell membranes of bacteria, fungi, viruses, and parasites, and can act as opsonin by activating the complement system and phagocytic...
    13 KB (1,529 words) - 16:21, 14 March 2024
  • Thumbnail for Properdin
    Properdin (category Complement system)
    producing anaphylatoxins, opsonins, chemotactic factors, and the membrane attack complex, all of which help fight pathogens. Properdin was discovered in...
    3 KB (418 words) - 01:13, 3 September 2023
  • Thumbnail for Innate immune system
    called cytokines activate the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells identify and...
    43 KB (4,797 words) - 02:27, 24 September 2024
  • Cambridge Tulsa Community College Terminal complement complex, the membrane attack complex of the complement system Thermomechanical Cuttings Cleaner Total...
    2 KB (265 words) - 23:20, 6 September 2024