cross-coupling reaction is a reaction where two different fragments are joined. Cross-couplings are a subset of the more general coupling reactions....
17 KB (1,499 words) - 13:48, 28 July 2024
These reactions are also called cross-coupling reactions. The product is unsymmetrical, R−R'. Coupling reactions are illustrated by the Ullmann reaction: Coupling...
7 KB (445 words) - 00:36, 18 April 2024
The Suzuki reaction or Suzuki coupling is an organic reaction that uses a palladium complex catalyst to cross-couple a boronic acid to an organohalide...
34 KB (3,845 words) - 17:47, 26 September 2024
The Sonogashira reaction is a cross-coupling reaction used in organic synthesis to form carbon–carbon bonds. It employs a palladium catalyst as well as...
48 KB (5,450 words) - 14:18, 26 September 2024
The Negishi coupling is a widely employed transition metal catalyzed cross-coupling reaction. The reaction couples organic halides or triflates with organozinc...
34 KB (3,954 words) - 20:12, 15 June 2024
chemistry, the Kumada coupling is a type of cross coupling reaction, useful for generating carbon–carbon bonds by the reaction of a Grignard reagent and...
20 KB (2,238 words) - 06:43, 11 January 2024
cross-coupling reactions. The Heck reaction is a way to substitute alkenes. The original reaction by Tsutomu Mizoroki (1971) describes the coupling between...
13 KB (1,355 words) - 19:29, 15 December 2023
product of this reaction when done with acetone as reagent. The reaction is usually a homocoupling but intramolecular cross-coupling reactions are also possible...
8 KB (891 words) - 19:54, 11 March 2024
Decarboxylative cross coupling reactions are chemical reactions in which a carboxylic acid is reacted with an organic halide to form a new carbon-carbon...
25 KB (3,056 words) - 03:04, 30 March 2022
The Hiyama coupling is a palladium-catalyzed cross-coupling reaction of organosilanes with organic halides used in organic chemistry to form carbon–carbon...
18 KB (1,972 words) - 06:30, 30 June 2023
The Chan–Lam coupling reaction – also known as the Chan–Evans–Lam coupling is a cross-coupling reaction between an aryl boronic acid and an alcohol or...
5 KB (622 words) - 17:13, 26 September 2024
The Stille reaction is a chemical reaction widely used in organic synthesis. The reaction involves the coupling of two organic groups, one of which is...
47 KB (5,491 words) - 13:23, 22 February 2024
The Glaser coupling is a type of coupling reaction. It is by far one of the oldest coupling reactions and is based on copper compounds like copper(I) chloride...
5 KB (587 words) - 15:31, 5 June 2024
Organogermanium compounds in cross-coupling reactions refers to a type of cross-coupling reaction where one of the coupling partners is an organogermanium...
13 KB (1,337 words) - 23:38, 28 August 2023
Buchwald–Hartwig amination (redirect from Buchwald–Hartwig coupling)
Buchwald–Hartwig amination is a chemical reaction for the synthesis of carbon–nitrogen bonds via the palladium-catalyzed coupling reactions of amines with aryl halides...
31 KB (3,483 words) - 01:36, 25 April 2024
Cross electrophile coupling is a type of cross-coupling reaction that occurs between two electrophiles. It is often catalyzed by transition metal catalyst(s)...
6 KB (698 words) - 15:18, 22 June 2024
Palladium–NHC complex (redirect from NHC-Palladium Complexes in Cross-Coupling)
investigated for applications in homogeneous catalysis, particularly cross-coupling reactions. The synthesis of Pd-NHC complexes follows the methods used for...
9 KB (915 words) - 09:34, 26 September 2024
position(s), followed a terminating cross-coupling reaction at the ipso position. This cross-coupling cascade reaction depends on the ortho-directing transient...
11 KB (1,156 words) - 22:20, 27 September 2024
Organozinc chemistry (redirect from Frankland-Duppa reaction)
transformations such as cross-coupling reactions, hydrogenation, and pericyclic reactions. In the absence of ligands, the reaction is slow and inefficient...
33 KB (3,394 words) - 06:05, 9 December 2023
The Ullmann reaction or Ullmann coupling, named after Fritz Ullmann, couples two aryl or alkyl groups with the help of copper. The reaction was first reported...
15 KB (1,600 words) - 19:18, 5 November 2024
in cross-coupling reactions / conjugate addition reactions of organoboronic acids (for C-C bond-forming reactions) and addition / coupling reactions of...
9 KB (1,071 words) - 18:10, 8 February 2023
coupling reaction is an organic reaction forming a new carbon–carbon bond from a thioester and a boronic acid using a metal catalyst. It is a cross-coupling...
12 KB (1,399 words) - 02:46, 6 March 2023
number of transition metal catalyzed cross-coupling reactions, such as the Heck coupling and the Sonogashira coupling (as illustrated below). Although triethylamine...
10 KB (809 words) - 11:18, 15 January 2024
Cross dehydrogenative coupling (also known as CDC reaction), coined by Chao-Jun Li of McGill University, is a type of coupling reaction allowing the construction...
6 KB (610 words) - 17:17, 5 June 2024
In cross-coupling reactions, the component reagents are called cross-coupling partners or simply coupling partners. These reagents can be further classified...
2 KB (217 words) - 15:17, 27 April 2023
The Cadiot–Chodkiewicz coupling in organic chemistry is a coupling reaction between a terminal alkyne and a haloalkyne catalyzed by a copper(I) salt such...
3 KB (293 words) - 16:22, 10 July 2024
palladium-catalyzed cross coupling reactions, copper was the preferred catalyst for almost a century. Palladium offers a faster, more selective reaction. Copper reagents...
23 KB (2,441 words) - 02:00, 1 August 2024
catalyzed ones, most commonly use Pd as the cross-coupling metal. Pd-catalyzed cross-coupling reactions catalyzed by a heterogeneous catalyst are thought...
20 KB (2,307 words) - 10:06, 26 September 2024
Miyaura borylation (category Organic redox reactions)
borylation reaction, is a named reaction in organic chemistry that allows for the generation of boronates from vinyl or aryl halides with the cross-coupling of...
6 KB (616 words) - 17:04, 7 March 2022
substitution (SNAr) with activated aryl halides. As a base in the cross-coupling reaction of aryl halides with terminal alkynes. It also plays a role in...
8 KB (586 words) - 21:15, 30 August 2024