Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein...
35 KB (4,314 words) - 00:26, 6 July 2024
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
35 KB (3,829 words) - 14:24, 17 June 2024
Cyclin-dependent kinase 4 also known as cell division protein kinase 4 is an enzyme that in humans is encoded by the CDK4 gene. CDK4 is a member of the...
21 KB (2,372 words) - 12:19, 28 July 2024
kinase 6 (CDK6) is an enzyme encoded by the CDK6 gene. It is regulated by cyclins, more specifically by Cyclin D proteins and Cyclin-dependent kinase...
35 KB (4,042 words) - 05:00, 1 April 2024
Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine...
24 KB (2,875 words) - 23:48, 3 December 2023
Cyclin-dependent kinase 9 or CDK9 is a cyclin-dependent kinase associated with P-TEFb. The protein encoded by this gene is a member of the cyclin-dependent...
12 KB (1,460 words) - 23:03, 27 March 2024
A cyclin-dependent kinase inhibitor protein (also known as CKIs, CDIs, or CDKIs) is a protein that inhibits the enzyme cyclin-dependent kinase (CDK) and...
10 KB (1,169 words) - 12:57, 29 July 2024
Cyclin-dependent kinase 5 is a protein, and more specifically an enzyme, that is encoded by the Cdk5 gene. It was discovered 15 years ago, and it is saliently...
42 KB (5,356 words) - 07:42, 8 May 2024
Cyclin-dependent kinase 7, or cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene...
20 KB (2,347 words) - 23:01, 27 March 2024
kinase 8 is an enzyme that in humans is encoded by the CDK8 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase...
21 KB (2,557 words) - 01:16, 24 April 2022
protein kinases". EMBO J. 11 (8): 2909–17. doi:10.1002/j.1460-2075.1992.tb05360.x. PMC 556772. PMID 1639063. "Entrez Gene: CDK3 cyclin-dependent kinase 3"...
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subunit of a protein kinase, cyclin-dependent kinase (CDK), with a regulatory subunit, cyclin. Once cyclin-dependent kinases bind to cyclin, the formed complex...
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of which contain multiple non-AUG translation initiation sites. Cyclin-dependent kinase 10 has been shown to interact with ETS2. GRCh38: Ensembl release...
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proteins that form holoenzymes with cyclin-dependent protein kinases (Cdk), which they activate. The abundance of cyclins is generally regulated by protein...
39 KB (4,605 words) - 22:37, 27 March 2024
Cyclin-dependent kinase inhibitor 1C (p57, Kip2), also known as CDKN1C, is a protein which in humans is encoded by the CDKN1C imprinted gene. Cyclin-dependent...
17 KB (2,000 words) - 14:41, 9 February 2024
RY (Jul–Aug 2003). "Cyclin-dependent kinases and S phase control in mammalian cells". Cell Cycle. 2 (4): 316–324. doi:10.4161/cc.2.4.468. PMID 12851482...
21 KB (2,578 words) - 02:36, 23 December 2023
In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...
27 KB (2,665 words) - 17:03, 6 April 2024
cycle and the centrosome cycle is mediated by cyclin-dependent kinase 2 (Cdk2). Cdk2 is a protein kinase (an enzyme) known to regulate the cell cycle....
18 KB (2,151 words) - 07:28, 24 February 2024
CDKN2A (redirect from Cyclin-dependent kinase inhibitor 2A)
CDKN2A, also known as cyclin-dependent kinase inhibitor 2A, is a gene which in humans is located at chromosome 9, band p21.3. It is ubiquitously expressed...
26 KB (3,317 words) - 18:16, 27 April 2024
(CDK/MAPK/GSK3/CLK) kinase group. The closest relatives of MAPKs are the cyclin-dependent kinases (CDKs). The first mitogen-activated protein kinase to be discovered...
46 KB (5,492 words) - 03:05, 21 June 2024
Cyclins are proteins that control the progression of a cell through the cell cycle by activating cyclin-dependent kinases (CDK). Cyclins were originally...
19 KB (1,760 words) - 23:49, 12 April 2024
Cyclin-dependent kinase 2-associated protein 1 is an enzyme that in humans is encoded by the CDK2AP1 gene. The protein encoded by this gene is a specific...
8 KB (1,047 words) - 05:24, 10 February 2024
Odajima J, Martín A, Dubus P, Sotillo R, et al. (September 2003). "Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in...
77 KB (9,017 words) - 09:38, 11 July 2024
the Kip/Cip family of CDK-inhibitor proteins. Cyclin-A1 interacts with: CDC20, Cyclin-dependent kinase 2, E2F1, GNB2L1, GPS2, MYBL2, and Retinoblastoma...
11 KB (1,435 words) - 20:58, 22 December 2023
Cyclin-dependent kinase inhibitor 1B (p27Kip1) is an enzyme inhibitor that in humans is encoded by the CDKN1B gene. It encodes a protein which belongs...
41 KB (5,152 words) - 05:27, 10 February 2024
cell cycle. Cyclins function as regulators of CDKs (cyclin-dependent kinase). Different cyclins exhibit distinct expression and degradation patterns...
49 KB (5,694 words) - 22:42, 27 March 2024
The Cyclin E/Cdk2 complex is a structure composed of two proteins, cyclin E and cyclin-dependent kinase 2 (Cdk2). Similar to other cyclin/Cdk complexes...
11 KB (1,334 words) - 08:40, 10 February 2024
media related to Kinases. Activation loop Autophosphorylation Ca2+/calmodulin-dependent protein kinase Cell signaling Cyclin-dependent kinase G protein-coupled...
33 KB (3,805 words) - 20:43, 22 July 2024
available. Cyclin E1 has been shown to interact with: CDC25A, CDKN1B, CUL3 Cdk1, Cyclin-dependent kinase 2, HERC5, P21, Retinoblastoma-like protein 2, and SMARCA4...
14 KB (1,720 words) - 21:44, 25 May 2024
Cyclin-dependent kinase inhibitor 3 is an enzyme that in humans is encoded by the CDKN3 gene. The protein encoded by this gene belongs to the dual specificity...
9 KB (1,041 words) - 02:33, 16 July 2024