Cysteinyl leukotriene receptor 1, also termed CYSLTR1, is a receptor for cysteinyl leukotrienes (LT) (see cysteinyl leukotrienes). CYSLTR1, by binding...
25 KB (3,101 words) - 22:04, 2 January 2024
Cysteinyl leukotriene receptor 2, also termed CYSLTR2, is a receptor for cysteinyl leukotrienes (LT) (see leukotrienes#Cysteinyl leukotrienes). CYSLTR2...
22 KB (2,678 words) - 11:07, 3 January 2024
Cysteinyl-leukotriene type 1 receptor antagonists, also known as CysLT1 antagonists, are a class of drugs that hinder the action of leukotriene by binding...
18 KB (1,802 words) - 09:05, 31 December 2023
The cysteinyl leukotriene receptors (CysLTRs) include the following two receptors: Cysteinyl leukotriene receptor 1 (CysLTR1) Cysteinyl leukotriene receptor...
997 bytes (82 words) - 01:26, 17 April 2022
wall Cysteinyl leukotriene receptors CYSLTR1 and CYSLTR2 are present on mast cells, eosinophil, and endothelial cells. During cysteinyl leukotriene interaction...
18 KB (1,957 words) - 18:25, 30 March 2024
Antileukotriene (redirect from Leukotriene receptor antagonist)
leukotriene receptor antagonist (cysteinyl leukotriene receptors) and consequently opposes the function of these inflammatory mediators; leukotrienes...
10 KB (1,070 words) - 02:56, 18 April 2024
LTB4R2 Cysteinyl leukotriene receptors (CysLTRs) – bind to and are activated by LTC4, LTD4, and LTE4: CysLT1 (Cysteinyl leukotriene receptor 1) – CYSLTR1...
2 KB (156 words) - 16:40, 3 May 2022
Zafirlukast (category Leukotriene antagonists)
treatment. Zafirlukast (brand name Accolate) was the first cysteinyl leukotriene receptor antagonist approved in the United States. It is now approved...
26 KB (2,524 words) - 16:38, 3 April 2024
Pharmacological agents that inhibit the function of these leukotrienes are leukotriene receptor antagonists (e.g., zafirlukast, montelukast) and are useful for asthmatic...
3 KB (80 words) - 00:28, 17 November 2023
Montelukast (category Leukotriene antagonists)
leukotriene receptor antagonist (cysteinyl leukotriene receptors) and consequently opposes the function of these inflammatory mediators; leukotrienes...
27 KB (2,283 words) - 22:41, 8 June 2024
OXGR1 (redirect from Cysteinyl leukotriene receptor E)
2-oxoglutarate receptor 1 (also known as GPR99, cysteinyl leukotriene receptor E, i.e., CysLTE, and cysteinyl leukotriene receptor 3, i.e., CysLT3)...
33 KB (4,235 words) - 01:55, 4 July 2024
Leukotriene A4 (LTA4) is a leukotriene, and is the precursor for the productions of leukotriene B4 (LTB4) and leukotriene C4 (LTC4). Following the biosynthesis...
7 KB (449 words) - 17:04, 30 March 2024
Leukotriene E4 (LTE4) is a cysteinyl leukotriene involved in inflammation. It is known to be produced by several types of white blood cells, including...
5 KB (439 words) - 23:50, 2 January 2024
The leukotriene B4 receptors (BLTRs) include the following two receptors: Leukotriene B4 receptor 1 (BLTR1) Leukotriene B4 receptor 2 (BLTR2) Eicosanoid...
464 bytes (27 words) - 16:40, 3 May 2022
elongation and unsaturation. AA is the precursor to some prostaglandins, leukotrienes (LTA, LTB, LTC), thromboxane (TXA) and the N-acylethanolamine (NAE)...
25 KB (2,240 words) - 20:48, 19 May 2024
Leukotriene B4 (LTB4) is a leukotriene involved in inflammation. It has been shown to promote insulin resistance in obese mice. LTB4 is a leukotriene...
4 KB (238 words) - 21:22, 13 April 2024
Pranlukast (category Leukotriene antagonists)
Pranlukast (brand name Onon, オノン) is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s montelukast (Singulair)...
4 KB (267 words) - 13:14, 9 January 2024
InterPro: IPR004071 Cysteinyl leukotriene receptor 1 (CYSLTR1) Cysteinyl leukotriene receptor 2 (CYSLTR2) Leukotriene B4 receptor InterPro: IPR003981 Leukotriene B4 receptor...
25 KB (2,172 words) - 01:01, 29 November 2023
Leukotriene-A4 hydrolase is an enzyme that catalyzes the reaction which converts Leukotriene A4 to Leukotriene B4. It is a bifunctional zinc enzyme (EC...
6 KB (595 words) - 08:01, 19 April 2024
GPR17 (category G protein-coupled receptors)
Uracil nucleotide/cysteinyl leukotriene receptor is a G protein-coupled receptor that in humans is encoded by the GPR17 gene located on chromosome 2 at...
14 KB (1,805 words) - 08:31, 17 October 2022
a) leukotriene A4 which is then metabolized to the chemotactic factor for leukocytes, leukotriene B4, or to contractors of lung airways, leukotriene C4...
3 KB (160 words) - 21:43, 1 April 2024
products LTD4 and LTE4. All three leukotrienes then bind at different affinities to two G-protein coupled receptors: CYSLTR1 and CYSLTR2, triggering pulmonary...
7 KB (563 words) - 02:22, 11 November 2023
turmeric root]. Journal de Pharmacie et des Sciences Accessoires (in French). 1: 289–300. available at Gallica. Farooqui, Tahira; Farooqui, Akhlaq A. (2019)...
27 KB (2,425 words) - 09:25, 2 May 2024
arachidonate 5-lipoxygenase produces no leukotrienes and the conversion by the enzyme of arachidonic acid to leukotrienes is inhibited. GLA is categorized as...
10 KB (979 words) - 20:33, 26 February 2024
Zileuton (category Leukotriene pathway inhibitors)
two compounds are leukotriene receptor antagonists which block the action of specific leukotrienes, while zileuton inhibits leukotriene formation. Research...
12 KB (1,248 words) - 19:30, 20 December 2023
Azelastine (category H1 receptor antagonists)
Azelastine, sold under the brand name Astelin among others, is a H1 receptor-blocking medication primarily used as a nasal spray to treat allergic rhinitis...
17 KB (1,277 words) - 05:29, 15 July 2024
CysLT1 (Cysteinyl leukotriene receptor 1) – CYSLTR1;CYSLTR1 is the receptor for Leukotriene C4 and Leukotriene D4; in binds and responds to leukotriene C4...
24 KB (2,893 words) - 07:17, 15 May 2024
"Protein Kinase C as the Receptor for the Phorbol Ester Tumor Promoters: Sixth Rhoads Memorial Award Lecture". Cancer Research. 48 (1): 1–8. PMID 3275491. Berg...
9 KB (925 words) - 10:07, 15 October 2023
the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological...
7 KB (889 words) - 10:11, 17 October 2022
which in turn converts to various leukotrienes (i.e., leukotriene B4, leukotriene C4, leukotriene D4, and leukotriene E4) as well as to 5-hydroxyeicosatetraenoic...
21 KB (1,882 words) - 06:27, 18 July 2024