• Thumbnail for DNA polymerase III holoenzyme
    DNA polymerase III holoenzyme is the primary enzyme complex involved in prokaryotic DNA replication. It was discovered by Thomas Kornberg (son of Arthur...
    7 KB (807 words) - 13:43, 10 December 2023
  • Thumbnail for DNA polymerase
    (including Φ29 DNA polymerase) and mitochondrial plasmids carry polB as well. DNA polymerase III holoenzyme is the primary enzyme involved in DNA replication...
    59 KB (7,090 words) - 06:49, 30 June 2024
  • Thumbnail for DNA clamp
    of the DNA polymerase III holoenzyme, the clamp protein binds DNA polymerase and prevents this enzyme from dissociating from the template DNA strand....
    23 KB (2,044 words) - 07:04, 10 March 2024
  • Thumbnail for DNA polymerase II
    DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA-dependent DNA polymerase encoded by the PolB gene. DNA Polymerase II is an...
    19 KB (2,328 words) - 05:16, 22 August 2024
  • Thumbnail for Polymerase
    ν Family B: DNA polymerase II; Pol α, δ, ε, ζ Family C: DNA polymerase III holoenzyme Family X: Pol β, λ, μ Terminal deoxynucleotidyl transferase (TDT)...
    7 KB (673 words) - 23:08, 9 July 2024
  • Thumbnail for DNA polymerase III, delta subunit
    structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme". Journal of Bacteriology. 174 (21): 7013–25. doi:10.1128/jb...
    2 KB (151 words) - 01:06, 29 November 2023
  • Thumbnail for Prokaryotic DNA replication
    is complete, DNA polymerase III holoenzyme is loaded into the DNA and replication begins. The catalytic mechanism of DNA polymerase III involves the use...
    17 KB (2,150 words) - 13:43, 23 June 2023
  • Thumbnail for DNA polymerase I
    DNA polymerase I (or Pol I) is an enzyme that participates in the process of prokaryotic DNA replication. Discovered by Arthur Kornberg in 1956, it was...
    15 KB (1,871 words) - 06:15, 30 May 2024
  • DNA polymerase epsilon is a member of the DNA polymerase family of enzymes found in eukaryotes. It is composed of the following four subunits: POLE (central...
    3 KB (336 words) - 09:50, 4 November 2023
  • process of DNA replication DNA polymerase II, a prokaryotic DNA-Dependent DNA polymerase encoded by the PolB gene DNA polymerase III holoenzyme, the primary...
    1 KB (209 words) - 23:59, 2 April 2016
  • dnaQ is the gene encoding the ε subunit of DNA polymerase III in Escherichia coli. The ε subunit is one of three core proteins in the DNA polymerase complex...
    9 KB (1,154 words) - 12:56, 18 August 2023
  • The τ and γ subunits are part of the DNA polymerase III holoenzyme of prokaryotes. The protein family is characterized by the well-conserved first N-terminal...
    2 KB (208 words) - 22:57, 28 January 2023
  • Thumbnail for Circular chromosome
    5 min with [3H]thymine and ['H]thymidine. [2]. The E. coli DNA polymerase III holoenzyme is a 900 kD complex, possessing an essentially a dimeric structure...
    21 KB (2,745 words) - 15:34, 29 June 2024
  • Thumbnail for DNA replication
    with Pol α. Multiple DNA polymerases take on different roles in the DNA replication process. In E. coli, DNA Pol III is the polymerase enzyme primarily responsible...
    60 KB (7,286 words) - 08:26, 2 July 2024
  • Thumbnail for DnaN
    O'Donnell M (June 1991). "Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme". J. Biol. Chem. 266 (17): 11328–34. PMID 2040637. v t e...
    3 KB (202 words) - 00:42, 9 December 2020
  • Thumbnail for RNA polymerase II
    RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA...
    27 KB (3,100 words) - 17:09, 21 April 2024
  • Thumbnail for RNA polymerase
    In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that...
    43 KB (5,103 words) - 08:16, 9 September 2024
  • RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding genes in living cells. It...
    37 KB (4,622 words) - 17:05, 6 April 2024
  • Thumbnail for POLE (gene)
    DNA polymerase epsilon catalytic subunit is an enzyme that in humans is encoded by the POLE gene. It is the central catalytic subunit of DNA polymerase...
    9 KB (1,103 words) - 12:15, 20 March 2024
  • Thumbnail for Transcription (biology)
    promoter escape occurs through DNA scrunching, providing the energy needed to break interactions between RNA polymerase holoenzyme and the promoter. In bacteria...
    58 KB (6,787 words) - 20:17, 9 August 2024
  • to interfere with Pol III holoenzyme processivity. This creates a checkpoint, stops replication, and allows time to repair DNA lesions via the appropriate...
    5 KB (559 words) - 03:25, 13 March 2023
  • vault large protein complexes: proteasome, DNA polymerase III holoenzyme, RNA polymerase II holoenzyme, symmetric viral capsids, complex of GroEL and...
    28 KB (2,365 words) - 16:48, 9 September 2024
  • Thumbnail for POLD3
    DNA polymerase delta subunit 3 is an enzyme that in humans is encoded by the POLD3 gene. It is a component of the DNA polymerase delta complex. POLD3 has...
    6 KB (740 words) - 17:22, 3 December 2023
  • Replicon (genetics) (category DNA replication)
    replicator is the entire DNA sequence (including, but not limited to the origin of replication) required to direct the initiation of DNA replication. The initiator...
    6 KB (634 words) - 22:52, 2 December 2023
  • Thumbnail for Origin of replication
    viruses utilize host cell DNA polymerases, which attach to a viral origin of replication if the T antigen is present. Although DNA replication is essential...
    113 KB (12,561 words) - 17:02, 14 May 2024
  • Thumbnail for Transcription preinitiation complex
    positions RNA polymerase II (Pol II) at gene transcription start sites, denatures the DNA, and positions the DNA in the RNA polymerase II active site...
    11 KB (1,210 words) - 12:30, 16 November 2023
  • Thumbnail for POLE4
    Polymerase (DNA-directed), epsilon 4, accessory subunit is a protein that in humans is encoded by the POLE4 gene. POLE4 is a histone-fold protein that...
    2 KB (264 words) - 20:32, 27 March 2024
  • Thumbnail for Promoter (genetics)
    promoter sequences are recognized only by RNA polymerase holoenzyme containing sigma-70. RNA polymerase holoenzymes containing other sigma factors recognize...
    54 KB (6,286 words) - 11:33, 8 August 2024
  • Thumbnail for Lambda phage
    Lambda phage (redirect from Lambda DNA)
    been released from the RNA polymerase holoenzyme. Part of the Qut site resembles the -10 Pribnow box, causing the holoenzyme to pause. Q protein then binds...
    54 KB (5,957 words) - 20:51, 23 July 2024
  • Thumbnail for Michael E. O'Donnell
    "Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp". Cell. 69 (3): 425–437. doi:10.1016/0092-8674(92)90445-i...
    6 KB (469 words) - 08:39, 6 July 2021