• Thumbnail for Denosumab
    Denosumab, sold under the brand names Prolia and Xgeva among others, is a human monoclonal antibody used for the treatment of osteoporosis, treatment-induced...
    26 KB (2,188 words) - 05:17, 13 June 2024
  • Thumbnail for RANKL
    RANKL (section Denosumab)
    some were given either 120 mg of denosumab or 4 mg of zoledronic acid. Patients who were given 120 mg of denosumab (in comparison to those who were given...
    28 KB (3,372 words) - 21:06, 8 March 2024
  • Thumbnail for Blythe Danner
    disparities exist. She has also appeared in commercials for Prolia, a brand of denosumab used in the treatment of osteoporosis. Danner was married to producer...
    33 KB (1,644 words) - 01:15, 3 July 2024
  • Thumbnail for Teriparatide
    imperfecta to reduce the risk of broken bones. Combined teriparatide and denosumab increased BMD more than either agent alone and more than has been reported...
    27 KB (2,054 words) - 06:31, 7 July 2024
  • Thumbnail for Hypocalcemia
    rhabdomyolysis, tumor lysis syndrome, and medications such as bisphosphonates or denosumab. Diagnosis should generally be confirmed by determining the corrected...
    19 KB (1,885 words) - 04:32, 21 March 2024
  • Thumbnail for Medication-related osteonecrosis of the jaw
    incident occurring in 2003. Osteonecrotic complications associated with denosumab, another antiresorptive drug from a different drug category, were soon...
    46 KB (4,835 words) - 18:24, 9 December 2023
  • 60-90% of patients who were treated for hypercalcemia of malignancy. Denosumab is a bone anti-resorptive agent that can be used to treat hypercalcemia...
    34 KB (3,298 words) - 03:10, 27 March 2024
  • Thumbnail for Osteolytic lesion
    tested in conjunction with calcium and vitamin D to encourage bone health. Denosumab, a monoclonal antibody treatment RANKl inhibitor that targets the osteocyte...
    6 KB (673 words) - 19:26, 15 September 2022
  • relating to the US Food and Drug Administration (FDA)-approved Sandoz denosumab biosimilars. On November 1, 1986, a major fire broke out in a warehouse...
    35 KB (2,761 words) - 03:18, 24 June 2024
  • Thumbnail for McCune–Albright syndrome
    it is no longer believed that they prevent progression of the disease. Denosumab has been found successful in reducing bone pain and decreasing tumor growth...
    22 KB (2,346 words) - 01:36, 8 March 2024
  • Thumbnail for Breast cancer
    metastases benefit from regular infusion of the bone-strengthening agents denosumab and the bisphosphonates; infusion every three months reduces the chance...
    129 KB (14,628 words) - 14:31, 8 July 2024
  • February 2024 adalimumab-ryvk/Simlandi adalimumab/Humira March 2024 denosumab-bbdz/Jubbonti denosumab/Prolia March 2024 denosumab-bbdz/Wyost denosumab/Xgeva...
    95 KB (6,480 words) - 22:51, 13 May 2024
  • baby's sex para-Dimethylaminobenzaldehyde, an organic chemical compound Denosumab, a drug for treating osteoporosis This disambiguation page lists articles...
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  • Thumbnail for Rheumatoid arthritis
    10913. PMC 5342346. PMID 27486885. Chiu YG, Ritchlin CT (January 2017). "Denosumab: targeting the RANKL pathway to treat rheumatoid arthritis". Expert Opinion...
    147 KB (17,113 words) - 14:30, 9 July 2024
  • Thumbnail for Prostate cancer
    they shrink tumors. Other bone modifying agents like zoledronic acid and denosumab can reduce prostate cancer bone pain, even though they have little effect...
    76 KB (8,857 words) - 11:18, 18 June 2024
  • Thumbnail for Merck & Co.
    PMID 24063695. S2CID 20163452. Gauthier K, Bai A, Perras C, et al. (2012). "Denosumab, Raloxifene, and Zoledronic Acid for the Treatment of Postmenopausal Osteoporosis:...
    96 KB (9,392 words) - 18:47, 3 July 2024
  • Thumbnail for Tumor necrosis factor
    Dulanermin Antibodies: Belimumab Brentuximab vedotin Conatumumab Dacetuzumab Denosumab Drozitumab Enavatuzumab Iratumumab Lexatumumab Lucatumumab Mapatumumab...
    52 KB (6,302 words) - 07:19, 27 April 2024
  • Thumbnail for Bone metastasis
    and bone-targeting chemotherapeutic agents such as bisphosphonates and denosumab. Orthopedic interventions such as internal fixation or spinal decompression...
    25 KB (2,653 words) - 20:55, 22 May 2024
  • Thumbnail for Daiichi Sankyo
    (esomeprazole) (only in Japan; marketed by AstraZeneca elsewhere) Pralia (denosumab) (only available in Japan; also sold there as Ranmark) Tarlige (mirogabalin)...
    29 KB (2,326 words) - 13:59, 3 May 2024
  • Thumbnail for Primary hyperparathyroidism
    osteoporosis such as estrogen replacement therapy, bisphosphonates or denosumab and for treatment hypercalciuria to reduce the risk for kidney stones...
    21 KB (2,314 words) - 02:26, 12 July 2024
  • Thumbnail for Giant-cell tumor of bone
    osteoclast-like cells. More recently, humanized monoclonal antibodies such as Denosumab targeting the RANK ligand have been employed in treatment of GCTOB in...
    14 KB (1,604 words) - 22:41, 29 February 2024
  • one year, and the benefit was maintained after a second year of taking denosumab. In the other, one year of romosozumab followed by one year of alendronate...
    12 KB (876 words) - 05:59, 15 July 2024
  • Thumbnail for NF-κB
    avenue of development for strategies targeting NF-κB inhibition. The drug denosumab acts to raise bone mineral density and reduce fracture rates in many patient...
    89 KB (9,817 words) - 08:00, 10 June 2024
  • in 2023. Products under development include biosimilars of omalizumab, denosumab, golimumab, aflibercept, vedolizumab, and pembrolizumab. In November 2022...
    11 KB (914 words) - 20:13, 22 June 2024
  • Thumbnail for Bisphosphonate
    C; Cunningham, J; Ahuja, T; Richter, T; Kovacs, C (February 2012). "Denosumab, Raloxifene, and Zoledronic Acid for the Treatment of Postmenopausal Osteoporosis:...
    30 KB (3,429 words) - 02:49, 1 January 2024
  • Pharmaceutical, Hetero Drugs, Roche Influenza Oct-1999 Mon-20XX 91 Xgeva Denosumab 197,711 3.24% Amgen Osteoporosis Nov-2010 Mon-20XX 92 Evista Raloxifene...
    29 KB (465 words) - 16:36, 9 July 2024
  • Thumbnail for Osteoporosis
    breast cancer, it increases the risk of blood clots and strokes. While denosumab is effective at preventing fractures in women, there is not clear evidence...
    124 KB (13,913 words) - 18:29, 16 June 2024
  • Thumbnail for Amgen
    (FDA approved 2008) Otezla (apremilast) Parsabiv (etelcalcetide) Prolia (denosumab) for postmenopausal osteoporosis Repatha (evolocumab) Riabni (rituximab-arrx)...
    95 KB (7,725 words) - 21:13, 5 July 2024
  • Thumbnail for Bladder cancer
    needed] People with bone metastasis should receive bisphosphonates or denosumab to prevent skeletal related events (e.g. fractures, spinal cord compression...
    130 KB (12,788 words) - 05:06, 8 July 2024
  • hypokalaemia, blood clots, interstitial lung disease and aseptic meningitis. Denosumab SC RANKL inhibitor. Osteoporosis, including drug- and cancer-related osteoporosis...
    52 KB (708 words) - 00:21, 11 April 2024