The dose–response relationship, or exposure–response relationship, describes the magnitude of the response of an organism, as a function of exposure (or...
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is a two-phased dose-response relationship to an environmental agent whereby low-dose amounts have a beneficial effect and high-dose amounts are either...
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intended to protect the health of consumers. The concept of a dose-response relationship dates back to as 1493 but its modern usage reaches to the 20th...
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Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. At extremely low doses, biological responses are...
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that linearizes the dose-response relationship. The Hill coefficient is a measure of ultrasensitivity (i.e. how steep is the response curve). The Hill coefficient...
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Linear no-threshold model (redirect from Maximum permissible dose)
The linear no-threshold model (LNT) is a dose-response model used in radiation protection to estimate stochastic health effects such as radiation-induced...
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Pharmacodynamics places particular emphasis on dose–response relationships, that is, the relationships between drug concentration and effect. One dominant...
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Dose–Response is a quarterly peer-reviewed scientific journal covering research on the dose-response relationship, especially hormesis. It was established...
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higher statin doses, a similarly low increase in muscle pain and weakness was present (5%) with no clear evidence of a dose-response relationship. Duration...
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effects. In summary, the effects of response-dependent drug dosing greatly differ from response-independent drug dosing and self-administration studies appropriately...
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severity and onset of chloracne may follow a typical asymptotic dose-response relationship curve. Chloracne normally results from direct skin contact with...
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S (2001). "Liquorice-induced rise in blood pressure: a linear dose-response relationship". Journal of Human Hypertension. 15 (8): 549–52. doi:10.1038/sj...
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disaster Discrepancy reporting, in software project management Dose–response relationship, the change in effect on an organism caused by differing levels...
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of the voltage gated sodium channel. Seong et al. also find a dose–response relationship of resistance to L925I copy number. Kolb, Adam; Needham, Glen...
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of that drug. The IC50 of a drug can be determined by constructing a dose-response curve and examining the effect of different concentrations of antagonist...
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Homeopathy (redirect from Molecular dose)
may support the idea of dilution increasing potency, but the dose-response relationship outside the zone of hormesis declines with dilution as normal...
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vegetables." Additionally, an excessive intake of salt has a dose-response relationship with elevated blood pressure, increasing the risk of several cardiovascular...
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associations between these lifestyle issues and ACEs shows a dose response relationship with people having four or more ACEs have significantly more of...
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Cancer slope factor (section Risk Specific Dose (RSD))
weight-day, is generally reserved for use in the low-dose region of the dose-response relationship, that is, for exposures corresponding to risks less...
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indicate that the adaptive response is responsible for the shape of dose-response curve and can transform the linear relationship (LNT) into the hormetic...
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and manner of death. Human Performance toxicology examines the dose-response relationship between drugs present in the body and their effects. This field...
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and many other fields. Pharmacological dose response relationships are an application of stimulus-response models. Another field this model can be applied...
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Therapeutic index (redirect from Therapeutic dose)
sigmoidal dose–response curves. Thus, a favorable outcome in dose–response for tumor tissue is greater than that of normal tissue for the same dose, meaning...
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given specimen. Agonist–antagonist opioids Buprenorphine Codeine Dose–response relationship Pain ladder Weber–Fechner law Baker, Hans (2004). Illustrated...
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promotion, toxic responses appear to be typically dose-dependent within certain concentration ranges. A multiphasic dose–response relationship has also been...
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neurological effects from anticoagulant exposure. Results showed a dose–response relationship between anticoagulant exposure and minor neurological dysfunction...
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hypersensitivity hypothesis is also supported by evidence of a dose–response relationship, withdrawal effects, studies on D2 agonists and antagonists, animal...
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Chemotherapy (redirect from High-dose alkylating chemotherapy)
the 5-fluorouracil area under the curve versus dose relationship to develop a pharmacokinetic dosing algorithm for colorectal cancer patients receiving...
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blood plasma. In other words, it is the ratio of amount of drug in a body (dose) to concentration of the drug that is measured in blood, plasma, and un-bound...
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distribution in the study population, and dose-response relationships of the pollutants. A dose-response relationship is a function of the exposure parameter...
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