• Thumbnail for Dose–response relationship
    The doseresponse relationship, or exposure–response relationship, describes the magnitude of the response of an organism, as a function of exposure (or...
    17 KB (1,788 words) - 21:35, 5 September 2024
  • Thumbnail for Hormesis
    is a two-phased dose-response relationship to an environmental agent whereby low-dose amounts have a beneficial effect and high-dose amounts are either...
    32 KB (3,494 words) - 15:39, 15 November 2024
  • intended to protect the health of consumers. The concept of a dose-response relationship dates back to as 1493 but its modern usage reaches to the 20th...
    9 KB (1,288 words) - 00:39, 3 June 2024
  • Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. At extremely low doses, biological responses are...
    23 KB (2,910 words) - 06:26, 27 September 2023
  • Thumbnail for Hill equation (biochemistry)
    that linearizes the dose-response relationship. The Hill coefficient is a measure of ultrasensitivity (i.e. how steep is the response curve). The Hill coefficient...
    30 KB (3,330 words) - 13:07, 4 October 2024
  • Thumbnail for Linear no-threshold model
    The linear no-threshold model (LNT) is a dose-response model used in radiation protection to estimate stochastic health effects such as radiation-induced...
    39 KB (4,584 words) - 02:24, 25 July 2024
  • Thumbnail for Pharmacodynamics
    Pharmacodynamics places particular emphasis on doseresponse relationships, that is, the relationships between drug concentration and effect. One dominant...
    22 KB (2,581 words) - 04:42, 9 November 2024
  • DoseResponse is a quarterly peer-reviewed scientific journal covering research on the dose-response relationship, especially hormesis. It was established...
    3 KB (182 words) - 00:15, 26 April 2023
  • Thumbnail for Atorvastatin
    higher statin doses, a similarly low increase in muscle pain and weakness was present (5%) with no clear evidence of a dose-response relationship. Duration...
    100 KB (9,454 words) - 15:22, 12 November 2024
  • effects. In summary, the effects of response-dependent drug dosing greatly differ from response-independent drug dosing and self-administration studies appropriately...
    28 KB (3,793 words) - 13:02, 22 October 2024
  • Thumbnail for Chloracne
    severity and onset of chloracne may follow a typical asymptotic dose-response relationship curve. Chloracne normally results from direct skin contact with...
    12 KB (1,215 words) - 15:32, 26 October 2024
  • Thumbnail for Liquorice (confectionery)
    S (2001). "Liquorice-induced rise in blood pressure: a linear dose-response relationship". Journal of Human Hypertension. 15 (8): 549–52. doi:10.1038/sj...
    10 KB (1,017 words) - 21:15, 31 October 2024
  • disaster Discrepancy reporting, in software project management Doseresponse relationship, the change in effect on an organism caused by differing levels...
    3 KB (472 words) - 18:00, 22 November 2024
  • Thumbnail for Cimex lectularius
    of the voltage gated sodium channel. Seong et al. also find a doseresponse relationship of resistance to L925I copy number. Kolb, Adam; Needham, Glen...
    7 KB (821 words) - 04:11, 17 November 2024
  • Thumbnail for IC50
    of that drug. The IC50 of a drug can be determined by constructing a dose-response curve and examining the effect of different concentrations of antagonist...
    10 KB (1,084 words) - 20:25, 28 August 2024
  • Thumbnail for Homeopathy
    Homeopathy (redirect from Molecular dose)
    may support the idea of dilution increasing potency, but the dose-response relationship outside the zone of hormesis declines with dilution as normal...
    163 KB (16,297 words) - 19:20, 4 November 2024
  • Thumbnail for Salting (food)
    vegetables." Additionally, an excessive intake of salt has a dose-response relationship with elevated blood pressure, increasing the risk of several cardiovascular...
    10 KB (1,105 words) - 16:25, 30 September 2024
  • associations between these lifestyle issues and ACEs shows a dose response relationship with people having four or more ACEs have significantly more of...
    97 KB (10,946 words) - 19:21, 1 November 2024
  • weight-day, is generally reserved for use in the low-dose region of the dose-response relationship, that is, for exposures corresponding to risks less...
    8 KB (1,093 words) - 19:00, 23 August 2022
  • Thumbnail for Radiation hormesis
    indicate that the adaptive response is responsible for the shape of dose-response curve and can transform the linear relationship (LNT) into the hormetic...
    56 KB (6,794 words) - 17:08, 6 November 2024
  • Thumbnail for Forensic toxicology
    and manner of death. Human Performance toxicology examines the dose-response relationship between drugs present in the body and their effects. This field...
    19 KB (2,421 words) - 05:04, 27 June 2024
  • and many other fields. Pharmacological dose response relationships are an application of stimulus-response models. Another field this model can be applied...
    11 KB (1,309 words) - 13:00, 20 November 2024
  • sigmoidal doseresponse curves. Thus, a favorable outcome in doseresponse for tumor tissue is greater than that of normal tissue for the same dose, meaning...
    25 KB (3,220 words) - 09:30, 20 November 2024
  • given specimen. Agonist–antagonist opioids Buprenorphine Codeine Doseresponse relationship Pain ladder Weber–Fechner law Baker, Hans (2004). Illustrated...
    2 KB (248 words) - 03:22, 7 February 2022
  • Thumbnail for Dioxins and dioxin-like compounds
    promotion, toxic responses appear to be typically dose-dependent within certain concentration ranges. A multiphasic doseresponse relationship has also been...
    87 KB (10,772 words) - 08:23, 16 October 2024
  • Thumbnail for Coumarin
    neurological effects from anticoagulant exposure. Results showed a doseresponse relationship between anticoagulant exposure and minor neurological dysfunction...
    36 KB (2,944 words) - 15:13, 9 October 2024
  • Thumbnail for Tardive dyskinesia
    hypersensitivity hypothesis is also supported by evidence of a doseresponse relationship, withdrawal effects, studies on D2 agonists and antagonists, animal...
    37 KB (3,941 words) - 20:14, 14 November 2024
  • Thumbnail for Chemotherapy
    the 5-fluorouracil area under the curve versus dose relationship to develop a pharmacokinetic dosing algorithm for colorectal cancer patients receiving...
    155 KB (17,518 words) - 23:36, 26 October 2024
  • blood plasma. In other words, it is the ratio of amount of drug in a body (dose) to concentration of the drug that is measured in blood, plasma, and un-bound...
    9 KB (1,132 words) - 01:43, 6 November 2024
  • Thumbnail for Disease burden
    distribution in the study population, and dose-response relationships of the pollutants. A dose-response relationship is a function of the exposure parameter...
    30 KB (3,872 words) - 19:05, 21 September 2024