initiation factor 4A-I (also known as eIF4A1 or DDX2A) is a 46 kDa cytosolic protein that, in humans, is encoded by the EIF4A1 gene, which is located on chromosome...
24 KB (2,579 words) - 11:17, 11 September 2022
initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA...
16 KB (1,828 words) - 07:58, 10 March 2024
HGNC:24656 Q9UBQ5 4833 EIF3L HGNC:18138 Q9Y262 4834 EIF3M HGNC:24460 Q7L2H7 4835 EIF4A1 HGNC:3282 P60842 4836 EIF4A2 HGNC:3284 Q14240 4837 EIF4A3 HGNC:18683 P38919...
277 KB (17 words) - 23:17, 27 April 2024
Subunit MW (kDa)[A] Isoforms Key Features eIF4A 46 eIF4A1, eIF4A2, eIF4A3 DEAD-box RNA helicase. Binds mRNA, eIF4G, eIF4B, eIF4H, and PDCD4. Inhibited...
7 KB (683 words) - 01:49, 14 June 2024
contain many RNA helicases, including the DEAD/H-box helicases Ded1p/DDX3, eIF4A1, and RHAU. In yeast, catalytic ded1 mutant alleles give rise to constitutive...
183 KB (12,458 words) - 20:40, 1 July 2024
layer, CTIP2-expressing ones. Moreover, IRE1α controls the proteostasis of eIF4A1 to drive translation of neuronal subtype determinants. GRCh38: Ensembl release...
22 KB (2,090 words) - 02:39, 16 July 2024
formerly EIF3S4 EIF3G EIF3I EIF3H EIF3J EIF3K EIF3L EIF3M EIF3S5 EIF3S8 EIF4A1 EIF4A2 EIF4A3 EIF4E2 EIF4G1 EIF4G2 EIF4G3 EIF4H EIF5 EIF5 EIF5A EIF5AL1...
48 KB (4,612 words) - 23:41, 12 December 2023
U1445 in 18S rRNA. This RNA is expressed from the intron of the host gene EIF4A1. Kiss, T (2002). "Small nucleolar RNAs: an abundant group of noncoding RNAs...
2 KB (140 words) - 19:20, 27 October 2021
ACA48 and U67, and the C/D box snoRNA mgU6-77, share the same host gene (EIF4A1). Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation...
2 KB (174 words) - 20:25, 28 January 2023
Miyashita A, Shimizu N, Endo N, et al. (1999). "Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse...
5 KB (601 words) - 10:27, 25 July 2024
for the initiation of translation. EIF4E has been shown to interact with: EIF4A1, EIF4EBP1, EIF4EBP2, EIF4EBP3, EIF4ENIF1, EIF4G1, and EIF4G2. . Other direct...
77 KB (8,382 words) - 22:32, 1 September 2024
translation initiation factor 4 gamma has been shown to interact with MKNK1, EIF4A1, EIF4E, MKNK2 and PABPC1. Eukaryotic initiation factor GRCh38: Ensembl release...
13 KB (1,672 words) - 03:36, 23 December 2023