Electrophilic aromatic substitution (SEAr) is an organic reaction in which an atom that is attached to an aromatic system (usually hydrogen) is replaced...

compounds can undergo electrophilic substitution as well. In electrophilic substitution in aromatic compounds, an atom appended to the aromatic ring, usually...

Electrophiles are involved in electrophilic substitution reactions, particularly in electrophilic aromatic substitutions. In this example, the benzene...

A nucleophilic aromatic substitution (SNAr) is a substitution reaction in organic chemistry in which the nucleophile displaces a good leaving group, such...

In electrophilic aromatic substitution reactions, existing substituent groups on the aromatic ring influence the overall reaction rate or have a directing...

flame, due to high C:H ratio Undergo electrophilic substitution reactions and nucleophilic aromatic substitutions Arenes are typically split into two categories...

the same ring position in an intermediate compound in an electrophilic aromatic substitution. Trimethylsilyl, tert-butyl, and isopropyl groups can form...

Electrophilic attack to an aromatic system results in electrophilic aromatic substitution rather than an addition reaction. Typical electrophilic additions...

to prevent electrophilic aromatic substitution. They can also be installed as directing groups to affect the position where a substitution may take place...

chemistry, an electrophilic aromatic halogenation is a type of electrophilic aromatic substitution. This organic reaction is typical of aromatic compounds...

Electron-withdrawing groups also tend to reduce Lewis basicity. Electrophilic aromatic substitution is famously affected by EWGs. The effect is transmitted by...

seven years later by J. J. Thomson. Second, he is describing electrophilic aromatic substitution, proceeding (third) through a Wheland intermediate, in which...

caused by substitution of anilines to become weaker bases, compared to substitution of isomers in the meta and para position. Electrophilic aromatic substitution...

or tetranitrated. The substituents on aromatic rings affect the rate of this electrophilic aromatic substitution. Deactivating groups such as other nitro...

of aromatic compounds. It is toxic to humans. Relative to benzene, it is electron-rich. It thus participates more rapidly in electrophilic aromatic substitution...

NO+2, which is important in nitration reactions involving electrophilic aromatic substitution. This type of reaction, where protonation occurs on an oxygen...

cyclohexadienyl cation that appears as a reactive intermediate in electrophilic aromatic substitution. For historic reasons this complex is also called a Wheland...

aromatic ring. Friedel–Crafts reactions are of two main types: alkylation reactions and acylation reactions. Both proceed by electrophilic aromatic substitution...

The Bischler–Napieralski reaction is an intramolecular electrophilic aromatic substitution reaction that allows for the cyclization of β-arylethylamides...

Directed ortho metalation (DoM) is an adaptation of electrophilic aromatic substitution in which electrophiles attach themselves exclusively to the ortho-...

θ-Hexachlorocyclohexane Chlorination of benzene under electrophilic aromatic substitution conditions (Cl2/FeCl3 or Cl2/AlCl3) produces chlorobenzene...

great catalyst at low Lewis acid loadings for electrophilic aromatic substitution and nucleophilic substitution reactions. The compound was first synthesized...

of nitro groups in aromatic compounds retards electrophilic aromatic substitution but facilitates nucleophilic aromatic substitution. Nitro groups are...

complementary to electrophilic aromatic substitution. The Sandmeyer reaction is an example of a radical-nucleophilic aromatic substitution (SRNAr). The radical...

Quelet reaction is an example of a larger class of reaction, electrophilic aromatic substitution. The reaction is named after its creator R. Quelet, who first...

common reactions of benzene involve substitution of a proton by other groups. Electrophilic aromatic substitution is a general method of derivatizing...

associated with electrophilic aromatic substitution reactions and the products follow the arene substitution pattern. So, a given substituted phenyl compound...

compound (R−N≡N+) and another aromatic compound that produces an azo compound (R−N=N−R’). In this electrophilic aromatic substitution reaction, the aryldiazonium...

electrofuges), like H+ or SiR+3, which commonly depart in electrophilic aromatic substitution reactions. Similarly, species of high thermodynamic stability...

reaction takes place almost exclusively in aromatic hydrocarbons, where it is called electrophilic aromatic substitution. The electrophile attack results in...