Epithelial cell adhesion molecule (EpCAM), also known as CD326 among other names, is a transmembrane glycoprotein mediating Ca2+-independent homotypic...
20 KB (2,451 words) - 12:05, 4 April 2024
Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular...
16 KB (1,905 words) - 07:17, 26 April 2024
Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process...
32 KB (3,663 words) - 08:18, 10 June 2024
transport. Cell junctions are especially abundant in epithelial tissues. Combined with cell adhesion molecules and extracellular matrix, cell junctions...
20 KB (2,248 words) - 10:19, 16 July 2024
The epithelial–mesenchymal transition (EMT) is a process by which epithelial cells lose their cell polarity and cell–cell adhesion, and gain migratory...
59 KB (6,833 words) - 23:23, 18 May 2024
to aid in the diagnosis of basal cell carcinoma (BCC). It is an antibody to EpCAM (epithelial cell adhesion molecule). BerEp4 has a high sensitivity and...
3 KB (210 words) - 23:22, 15 December 2021
ICAM-1 (redirect from Intercellular adhesion molecule 1)
ICAM-1 (Intercellular Adhesion Molecule 1) also known as CD54 (Cluster of Differentiation 54) is a protein that in humans is encoded by the ICAM1 gene...
19 KB (2,409 words) - 16:20, 11 December 2023
Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene. Cell adhesion molecule 1 has been shown to interact with EPB41L3...
13 KB (1,186 words) - 06:39, 18 December 2023
(July 2009). Mullins, Mary C (ed.). "The Epithelial Cell Adhesion Molecule EpCAM Is Required for Epithelial Morphogenesis and Integrity during Zebrafish...
14 KB (1,710 words) - 12:42, 11 July 2024
reprogramming. Epithelial-associated genes such as E-cadherin/Cdh1, Cldns −3, −4, −7, −11, Occludin (Ocln), Epithelial cell adhesion molecule (Epcam), and...
14 KB (1,600 words) - 04:00, 19 August 2023
(epithelial cell adhesion molecule, ESA, TROP1) is hemophilic Ca2+-independent cell adhesion molecule expressed on the basolateral surface of most epithelial cells...
86 KB (10,308 words) - 12:49, 12 July 2024
Morphogenesis (section Cell-to-cell adhesion)
same adhesion molecule can sort out. The molecules responsible for adhesion are called cell adhesion molecules (CAMs). Several types of cell adhesion molecules...
25 KB (2,724 words) - 18:06, 10 August 2024
and tension to cells and tissues and they are also the site of cell-cell signaling. Adherens junctions are made of cell adhesion molecules from the cadherin...
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monoclonal antibody which is used to target tumor cells. It binds to the epithelial cell adhesion molecule (EpCAM - CD326), with the intent to trigger antibody-dependent...
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as cell adhesion, ion conductivity, and cell signalling and serve as the attachment surface for several extracellular structures, including the cell wall...
59 KB (6,903 words) - 13:20, 9 August 2024
mesothelium consists of a single layer of flattened to cuboidal cells forming the epithelial lining of the serous cavities of the body including the peritoneal...
96 KB (10,697 words) - 06:49, 13 May 2024
transport of molecules across the epithelial sheet. How epithelial cells generate and maintain polarity remains unclear, but certain molecules have been...
10 KB (1,305 words) - 22:43, 4 February 2024
hydrophilic molecules. As such they are unable to diffuse freely across the bi-lipid layer of the plasma membrane, so their action is mediated by a cell membrane...
62 KB (6,781 words) - 14:13, 22 July 2024
A junctional adhesion molecule (JAM) is a protein that is a member of the immunoglobulin superfamily, and is expressed in a variety of different tissues...
15 KB (1,824 words) - 07:31, 26 August 2023
cytokines. Many types of cancer cells carry EpCAM (epithelial cell adhesion molecule) on their surface. By binding to such a cell via one arm, to a T lymphocyte...
8 KB (709 words) - 20:33, 1 December 2023
discovery of cadherin cell-cell adhesion proteins is attributed to Masatoshi Takeichi, whose experience with adhering epithelial cells began in 1966. His...
55 KB (6,434 words) - 22:24, 2 May 2024
variable fragment of a monoclonal antibody which binds to epithelial cell adhesion molecule (EpCAM, the tumor-associated calcium signal transducer 1)...
3 KB (225 words) - 23:43, 17 July 2024
Basal cell adhesion molecule, also known as Lutheran antigen, is a plasma membrane glycoprotein that in humans is encoded by the BCAM gene. BCAM has also...
10 KB (1,272 words) - 11:36, 24 July 2024
Cadherin (category Cell adhesion proteins)
(named for "calcium-dependent adhesion") are cell adhesion molecules important in forming adherens junctions that let cells adhere to each other. Cadherins...
32 KB (3,594 words) - 14:17, 13 May 2024
Catenin beta-1 (section Role in cell–cell adhesion)
dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by...
107 KB (12,362 words) - 22:48, 10 July 2024
Intestinal epithelium (redirect from Gastrointestinal epithelial cell)
other molecules into or out of the cell. Paracellular permeability depends on transport through the spaces that exist between epithelial cells. It is...
26 KB (2,933 words) - 06:35, 22 June 2024
Nectin-3 (category Cell adhesion molecules)
Nectin-3, also known as nectin cell adhesion molecule 3, is a protein that in humans is encoded by the NECTIN3 gene. Nectin-3 belongs to the family of...
14 KB (1,766 words) - 16:05, 25 July 2024
Ovarian cancer (redirect from Ovarian epithelial cancer)
ovary is made up of three different cell types including epithelial cells, germ cells, and stromal cells. When these cells become abnormal, they have the ability...
197 KB (21,096 words) - 06:27, 9 August 2024
Implantation (embryology) (section Adhesion)
extracellular domain that are ligands of L-selectin, a cell adhesion molecule on the surface of trophoblast cells. An in vitro model of implantation gave evidence...
51 KB (5,887 words) - 09:03, 14 July 2024
2012). "Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma". Journal...
20 KB (2,168 words) - 11:19, 1 July 2024