• Thumbnail for Estrogen receptor alpha
    Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a...
    58 KB (6,133 words) - 06:55, 2 November 2024
  • Thumbnail for Estrogen receptor
    Estrogen receptors (ERs) are proteins found in cells that function as receptors for the hormone estrogen (17β-estradiol). There are two main classes of...
    38 KB (4,058 words) - 04:20, 19 October 2024
  • Thumbnail for Estrogen-related receptor alpha
    Estrogen-related receptor alpha (ERRα), also known as NR3B1 (nuclear receptor subfamily 3, group B, member 1), is a nuclear receptor that in humans is...
    17 KB (1,995 words) - 21:24, 29 March 2024
  • Thumbnail for Estrogen receptor beta
    Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear...
    39 KB (4,526 words) - 06:00, 25 July 2024
  • Thumbnail for Estrogen insensitivity syndrome
    caused by a defective estrogen receptor (ER) – specifically, the estrogen receptor alpha (ERα) – that results in an inability of estrogen to mediate its biological...
    35 KB (3,802 words) - 22:12, 6 September 2024
  • Thumbnail for Membrane estrogen receptor
    Membrane estrogen receptors (mERs) are a group of receptors which bind estrogen. Unlike nuclear estrogen receptors, which mediate their effects via slower...
    19 KB (1,985 words) - 03:22, 24 May 2024
  • Thumbnail for Nuclear receptor
    of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha". Journal of Medicinal Chemistry. 47 (23): 5593–6. doi:10...
    74 KB (6,683 words) - 09:55, 12 September 2024
  • Thumbnail for Camizestrant
    Camizestrant (category Selective estrogen receptor degraders)
    evaluated to treat breast cancer. It is an estrogen receptor alpha antagonist and a selective estrogen receptor degrader (SERD). "Camizestrant - AstraZeneca"...
    3 KB (84 words) - 08:50, 3 November 2024
  • estrogen receptor (ER): estrogen receptor alpha (ERα), and estrogen receptor beta (ER-β), also known as NR3A2. Both are nuclear receptors activated by the sex...
    10 KB (1,332 words) - 19:38, 30 June 2024
  • Thumbnail for Estrogen
    they bind to and activate estrogen receptors (ERs) which in turn modulate the expression of many genes. Additionally, estrogens bind to and activate rapid-signaling...
    73 KB (7,787 words) - 14:58, 29 October 2024
  • Thumbnail for Estrogen-related receptor beta
    Estrogen-related receptor beta (ERR-β), also known as ESRRB or NR3B2 (nuclear receptor subfamily 3, group B, member 2), is a nuclear receptor that in...
    7 KB (800 words) - 19:11, 27 March 2024
  • Cardenas J, Podvinec M, Oakeley EJ, Kralli A (April 2004). "The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced...
    11 KB (1,175 words) - 13:05, 3 December 2023
  • alpha-1 (α1) adrenergic receptors are G protein-coupled receptors (GPCRs) associated with the Gq heterotrimeric G protein. α1-adrenergic receptors are...
    16 KB (1,528 words) - 10:28, 23 June 2024
  • Thumbnail for Selective estrogen receptor modulator
    Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs), are a class of drugs that act on estrogen receptors...
    56 KB (6,362 words) - 22:03, 21 October 2024
  • studied steroid hormone receptors are members of the nuclear receptor subfamily 3 (NR3) that include receptors for estrogen (group NR3A) and 3-ketosteroids...
    23 KB (2,796 words) - 19:08, 19 February 2024
  • Thumbnail for Adrenergic receptor
    agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example. Many cells have these receptors, and the binding...
    33 KB (2,982 words) - 11:42, 7 August 2024
  • proliferation and apoptosis. It also decreases the expression of estrogen receptor alpha in ER-positive breast cancer. Polyamine oxidase Polyamines in plant...
    15 KB (1,645 words) - 14:28, 22 June 2024
  • Thumbnail for Elacestrant
    Elacestrant (category Selective estrogen receptor degraders)
    antagonist of estrogen receptors, specifically targeting the estrogen receptor alpha (ERα), which is the biological target of endogenous estrogens like estradiol...
    13 KB (917 words) - 11:59, 21 October 2024
  • Thumbnail for Primary transcript
    study involved estrogen receptors and differential splicing. The article entitled, "Alternative splicing of the human estrogen receptor alpha primary transcript:...
    22 KB (2,660 words) - 06:39, 29 October 2024
  • Thumbnail for Cadmium
    For example, cadmium can bind to the estrogen receptor alpha, and affect signal transduction along the estrogen and MAPK signaling pathways at low doses...
    66 KB (7,370 words) - 02:36, 30 October 2024
  • factors on mammary gland development and differentiation in the estrogen receptor-alpha knockout (ERKO) mouse". Breast Cancer Res. Treat. 79 (2): 161–73...
    59 KB (6,495 words) - 08:42, 1 July 2024
  • Thumbnail for Estrogen and neurodegenerative diseases
    mediated by binding to two receptors: Estrogen Receptor alpha (ERα) and Estrogen Receptor beta (ERβ). These two receptors are tissue specific and have...
    19 KB (2,223 words) - 00:10, 29 October 2024
  • Androgen receptors Calcitriol receptors Corticotropin-releasing hormone receptor 1 Corticotropin releasing hormone receptor 2 Estrogen receptors Follicle-stimulating...
    17 KB (2,005 words) - 23:01, 20 August 2024
  • Thumbnail for Gonadotropin-releasing hormone
    be regulated by estrogen. It has been reported that there are kisspeptin-producing neurons that also express estrogen receptor alpha. GnRH is found in...
    27 KB (3,150 words) - 08:47, 11 April 2024
  • et al. (2010). "Estrogen-induced sexual incentive motivation, proceptivity and receptivity depend on a functional estrogen receptor [alpha] in the ventromedial...
    48 KB (5,694 words) - 08:08, 29 September 2024
  • Thumbnail for Equol
    binding affinity for human estrogen receptor alpha (ERα) and 20% of estradiol's binding affinity for human estrogen receptor beta (ERβ). The preferential...
    24 KB (2,667 words) - 21:44, 28 February 2024
  • Thumbnail for Epidermal growth factor receptor
    factors on mammary gland development and differentiation in the estrogen receptor-alpha knockout (ERKO) mouse". Breast Cancer Research and Treatment. 79...
    60 KB (6,879 words) - 14:26, 16 July 2024
  • Thumbnail for Aryl hydrocarbon receptor
    HI (January 2000). "The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1". Archives of Biochemistry...
    52 KB (5,968 words) - 15:15, 4 June 2024
  • Thumbnail for Pparg coactivator 1 alpha
    protein Estrogen-related receptor alpha (ERRα), estrogen-related receptor beta (ERR-β), estrogen-related receptor gamma (ERR-γ). Farnesoid X receptor FBXW7...
    32 KB (3,863 words) - 10:06, 3 November 2024
  • Thumbnail for Alfatradiol
    sold under the brand names Avicis, Avixis, Ell-Cranell Alpha, and Pantostin, is a weak estrogen and 5α-reductase inhibitor medication which is used topically...
    14 KB (1,217 words) - 10:26, 21 October 2024