• Thumbnail for Galectin-1
    Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. LGALS1 contains four exons. The galectin-1 protein is 135 amino acids in length and...
    8 KB (922 words) - 18:36, 20 November 2023
  • Thumbnail for Galectin
    Galectins are a class of proteins that bind specifically to β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which...
    34 KB (3,864 words) - 01:49, 22 June 2024
  • Thumbnail for Galectin-3
    Galectin-3 is a protein that in humans is encoded by the LGALS3 gene. Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have...
    25 KB (2,839 words) - 08:50, 18 May 2024
  • used to infect human NSCs (hNSCs) with Galectin-1 which were later transplanted into the damaged tissue. The hGal-1-hNSCs induced better and faster brain...
    35 KB (4,177 words) - 02:23, 18 September 2024
  • glycolysis in these tumors is probably related to their aggressive biology. Galectin-1 in TNBC is a beta-galactosidase-binding protein that shields cancer cells...
    28 KB (3,411 words) - 03:40, 14 June 2024
  • Thumbnail for Galectin-9
    Galectin-9 was first isolated from mouse embryonic kidney in 1997 as a 36 kDa beta-galactoside lectin protein. Human galectin-9 is encoded by the LGALS9...
    18 KB (2,173 words) - 06:45, 14 August 2024
  • Thumbnail for Galectin-4
    Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating...
    12 KB (1,609 words) - 14:15, 29 September 2022
  • Thumbnail for LGALS3BP
    Galectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene. The galectins are a family of beta-galactoside-binding proteins...
    9 KB (1,111 words) - 20:42, 13 October 2022
  • such as PD-L1 and PD-L2, heme oxygenase 1, HLA-G, CD95L, TNF-related apoptosis inducing ligands, galectin-1 and DC-SIGN and production of immunosuppressive...
    23 KB (2,765 words) - 17:17, 20 November 2023
  • how such tumors can be regressed. He also looked at the properties of galectins, and how they show potential for disease. Rabinovich was born in Córdoba...
    12 KB (1,339 words) - 06:38, 29 April 2024
  • Thumbnail for Fibroblast growth factor 23
    Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States...
    16 KB (1,840 words) - 09:33, 21 September 2024
  • Thumbnail for Galectin-8
    Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene. This gene encodes a member of the galectin family. Galectins...
    10 KB (1,213 words) - 02:35, 16 July 2024
  • Thumbnail for Galectin-2
    Galectin-2 is a protein that in humans is encoded by the LGALS2 gene. The protein encoded by this gene is a soluble beta-galactoside binding lectin. The...
    6 KB (785 words) - 22:29, 2 December 2023
  • spina bifida. In 2019, Farmer and Aijun Wang identified exosomes and galectin 1 as key to protecting neurons and ultimately reducing the lower-limb paralysis...
    7 KB (686 words) - 18:22, 11 August 2024
  • major classes of mammalian glycan-binding proteins (GBPs): C-type lectin, galectin, and SIGLEC immune receptors that bind carbohydrates: CD1, T cell receptor...
    14 KB (1,768 words) - 00:46, 22 June 2024
  • Thumbnail for Galectin-7
    Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating...
    5 KB (699 words) - 05:53, 3 January 2024
  • Thumbnail for ROMK
    Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States...
    14 KB (1,756 words) - 10:15, 6 January 2024
  • Thumbnail for Endothelial cell anergy
    proteins that can deliver death signals in leukocytes (Fas ligand and galectin-1). The formation of a leukocyte infiltrate at places of inflammation is...
    8 KB (786 words) - 14:19, 21 August 2023
  • targeted drugs. Following this, Shipp's research team found that serum galectin-1 levels were "significantly associated with tumor burden and additional...
    6 KB (518 words) - 14:15, 26 February 2024
  • Molecular and Cellular Biology (2008) 4377–4385. Belanis L, et al., Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters...
    35 KB (4,425 words) - 05:58, 29 December 2023
  • Thumbnail for Gem-associated protein 4
    Grabski S, Wang JL, Patterson RJ (September 2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic...
    9 KB (1,120 words) - 02:34, 16 July 2024
  • negatively selected to undergo apoptosis. The molecules like gal-3 (Galectin-3) and gal-1(Galectin-1), on the other hand, produce antagonistic effects. They inhibit...
    10 KB (1,482 words) - 12:14, 4 May 2022
  • Thumbnail for Yu-Jui Yvonne Wan
    America A publication entitled "Targeting stroma and tumor, silencing galectin-1 treats orthotopic mouse HCC" was featured in UC Davis Health News, November...
    11 KB (1,258 words) - 23:33, 22 September 2024
  • (HGF), Notch-1, sonic hedgehog (SHH), noggin, ciliary neurotrophic factor (CNTF), and a soluble carbohydrate-binding protein, Galectin-1, are reported...
    19 KB (2,444 words) - 16:04, 17 June 2024
  • matri-cellular proteins. The up regulation of matri-cellular proteins such as galectin-1, and tenascin-C is present in the stromal tissues of pancreatic cancer...
    20 KB (2,479 words) - 05:51, 15 May 2024
  • Thumbnail for CD43
    membrane microdomains occurs on human T cells during apoptosis induced by galectin-1". J. Immunol. 163 (7): 3801–11. doi:10.4049/jimmunol.163.7.3801. PMID 10490978...
    10 KB (1,283 words) - 06:43, 25 December 2023
  • Thumbnail for CD7
    membrane microdomains occurs on human T cells during apoptosis induced by galectin-1". Journal of Immunology. 163 (7): 3801–11. doi:10.4049/jimmunol.163.7...
    10 KB (1,221 words) - 05:59, 25 December 2023
  • Thumbnail for VPREB1
    PMID 11994467. Gauthier L, Rossi B, Roux F, Termine E, Schiff C (October 2002). "Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in...
    7 KB (1,043 words) - 14:25, 3 December 2023
  • Thumbnail for Small nuclear ribonucleoprotein D1
    1016/S1097-2765(01)00244-1. PMID 11389857. Park JW, Voss PG, Grabski S, Wang JL, Patterson RJ (Sep 2001). "Association of galectin-1 and galectin-3 with Gemin4 in...
    12 KB (1,522 words) - 06:23, 6 January 2024
  • Thumbnail for Charcot–Leyden crystals
    Charcot–Leyden crystals are microscopic crystals composed of eosinophil protein galectin-10 found in people who have allergic diseases such as asthma or parasitic...
    5 KB (436 words) - 04:13, 27 April 2024