• embryonic kidney 293 cells, also often referred to as HEK 293, HEK-293, 293 cells, are an immortalised cell line derived from HEK cells isolated from a...
    25 KB (3,066 words) - 13:23, 9 November 2024
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    cells – derived from a cancer patient lung tumor HeLa cells – a widely used human cell line isolated from cervical cancer patient Henrietta Lacks HEK...
    10 KB (1,139 words) - 17:57, 26 November 2024
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    outside the HEK 293 cells. For the production of the vaccine, to propagate adenoviral vectors in which the E1 gene was deleted, HEK 293 cells are used,...
    154 KB (13,917 words) - 20:05, 2 January 2025
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    cultured human embryonic kidney HEK 293 cells made to express any one of 351 different human G protein-coupled receptors, only cells expressing OXGR1 responded...
    85 KB (10,190 words) - 02:57, 26 December 2024
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    and plant cells, this process is carried out exclusively in peroxisomes. The first reactions in the formation of plasmalogen in animal cells also occur...
    33 KB (3,863 words) - 02:10, 9 December 2024
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    cytosines (epigenetic alterations) at these locations. Jiang et al. treated HEK 293 cells with agents causing oxidative DNA damage, (potassium bromate (KBrO3)...
    160 KB (18,278 words) - 05:12, 30 December 2024
  • turning point was in 2011, when Mader et al. developed a cell-based assay using HEK 293 cells which increased the detection rate of these antibodies in...
    27 KB (2,799 words) - 09:09, 23 October 2024
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    When these mutant channels are expressed in human embryonic kidney (HEK 293) cells, the resulting channels are five times more sensitive to activation...
    45 KB (4,933 words) - 15:34, 26 July 2024
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    with antibodies and T-cells if the virus later enters the body. To manufacture the vaccine the virus is propagated on HEK 293 cell lines and then purified...
    214 KB (17,080 words) - 15:51, 27 September 2024
  • Thumbnail for Lex van der Eb
    transfection of the cells with the adenovirus 5 this led to the cell line of HEK 293 cells. HEK 293 became one of the most used cell lines worldwide, coming...
    14 KB (1,256 words) - 03:28, 29 June 2024
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    neurons, expressed the clones in HEK 293 cells, and looked for cells that respond to capsaicin with calcium influx (which HEK-293 normally do not). After several...
    57 KB (6,739 words) - 01:29, 23 December 2024
  • Thumbnail for Glucagon-like peptide-1 receptor
    "Stimulation of cloned human glucagon-like peptide 1 receptor expressed in HEK 293 cells induces cAMP-dependent activation of calcium-induced calcium release"...
    33 KB (4,125 words) - 18:11, 23 December 2024
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    cytosines (epigenetic alterations) at these locations. Jiang et al. treated HEK 293 cells with agents causing oxidative DNA damage, (potassium bromate (KBrO3)...
    129 KB (15,900 words) - 16:37, 6 December 2024
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    "Inhibitory effect of protopine on K(ATP) channel subunits expressed in HEK-293 cells". European Journal of Pharmacology. 506 (2): 93–100. doi:10.1016/j.ejphar...
    5 KB (300 words) - 16:38, 9 September 2023
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    researchers subcutaneously implanted mice with microencapsulated transgenic HEK 293 cells that were cotransfected with two vectors including the melanopsin gene...
    39 KB (4,525 words) - 07:01, 5 April 2024
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    African iron overload (category Red blood cell disorders)
    and HEK 293 cells, the expression of wild type ferroportin was similar to the expression of ferroportin Q248H at the plasma membrane. In HEK 293 cells, Q248H...
    21 KB (2,166 words) - 15:37, 17 November 2024
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    norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants". The Journal of Experimental...
    33 KB (3,479 words) - 15:14, 27 September 2024
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    cells is genetically determined, but some cell-culturing cells have been 'transformed' into immortal cells which will reproduce indefinitely if the optimal...
    108 KB (8,466 words) - 10:22, 15 December 2024
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    Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells". Molecular Therapy. 23 (10): 1582–1591. doi:10.1038/mt.2015.123. PMC 4817922...
    37 KB (3,938 words) - 17:53, 10 November 2024
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    receptor couples to Gi/Go proteins and inhibits adenylate cyclase in HEK 293 cells". European Journal of Pharmacology. 361 (2–3): 299–309. doi:10...
    65 KB (5,263 words) - 07:14, 24 November 2024
  • retinal cells. Voretigene neparvovec is an AAV2 vector containing human RPE65 cDNA with a modified Kozak sequence. The virus is grown in HEK 293 cells and...
    14 KB (949 words) - 09:34, 29 September 2024
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    kidney (HEK) cells. Chinese hamster ovary cell Mouse myeloma lymphoblstoid (e.g. NS0 cell) Fully Human Human embryonic kidney cells (HEK-293) Human embryonic...
    25 KB (2,654 words) - 08:14, 28 October 2024
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    phenylethanolamine itself. Measurements of cAMP accumulation in intact transfected HEK 293 cells, after treatment with EEDQ to inactivate 98-99% of the receptors, indicated...
    17 KB (2,152 words) - 23:57, 2 July 2024
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    p53-independent manner in HeLa cells, human skeletal muscle cells, and adult rat cardiomyocytes. Using BNIP3 phosphomimetics in HEK 293 cells, researchers found that...
    21 KB (2,672 words) - 04:34, 2 November 2024
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    Baculovirus gene transfer into Mammalian cells (BacMam) is the use of a baculovirus to deliver genes to mammalian cells. Baculoviruses are insect viruses that...
    15 KB (1,675 words) - 12:14, 11 August 2024
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    amphetamine-induced endocytosis is independent of TAAR1 includes 1) HEK-293 cells do not express TAAR1 (Reese et al., 2007; Xie and Miller, 2007) but...
    181 KB (12,434 words) - 01:54, 19 December 2024
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    MRC-5 (category Human cell lines)
    inside a genetically normal human cell." The manufacturing of the vaccine used the HEK 293 fetal cell line, the kidney cells of an aborted or spontaneously...
    3 KB (330 words) - 04:12, 24 June 2023
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    dependent upon temperature and pH value, as has been shown in research with HEK 293 cells expressing TRPV1. The optimal pH value is around 7.8 to 8.0 and binding...
    8 KB (774 words) - 21:45, 13 August 2023
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    number of compounds on a rat trace amine receptor (rTAR1) expressed in HEK 293 cells, hordenine, at a concentration of 1 μM, had almost identical potency...
    27 KB (3,217 words) - 15:18, 9 December 2024
  • Thumbnail for Janssen COVID-19 vaccine
    Russian Sputnik V COVID-19 vaccine which use human embryonic kidney (HEK) 293 cells for adenovirus vector replication. The Ad26 viral vector lacks the E1...
    141 KB (11,331 words) - 06:12, 24 September 2024