In the management of HIV/AIDS, HIV capsid inhibitors are antiretroviral medicines that target the capsid shell of the virus. This is in contrast to most...

release of the HIV capsid into the cell. Entry to the cell begins through interaction of the trimeric envelope complex (gp160 spike) on the HIV viral envelope...

reverse-transcriptase inhibitors HIV capsid inhibition Arachchige AS (2021). "A universal CAR-NK cell approach for HIV eradication". AIMS Allergy and Immunology...

of the immunoproteasome enables human TRIM5α for effective capsid-dependent inhibition of HIV-1 DNA synthesis and infection. GRCh38: Ensembl release 89:...

therapeutic effect. Hence, inhibition of the HIV protease is one of the most important approaches for the therapeutic intervention in HIV infection and their...

protein cage called the capsid, which is wrapped in a lipid bilayer called the envelope. The envelope is joined to the capsid by means of a tegument....

Silva, Diane M.; Kast, W. Martin (2009-11-15). "A major role for the minor capsid protein of human papillomavirus type 16 in immune escape". Journal of Immunology...

acids within the capsid of HIV-1, helps integrate the viral RNA into budding virions, and is intimately involved in the replication of HIV-1 in both the...

nucleoside and deoxynucleoside analogues: inhibition of viral replication of sheep MVV (in vitro model for HIV) and bovine BHV-1". Bioorg. Med. Chem. 10...

This capsid has 161 capsomers consisting of 150 hexons and 11 pentons, as well as a portal complex that allows entry and exit of DNA into the capsid. All...

virus with a protein covering that packages its nucleic acids, called the capsid, which is then surrounded by an amorphous protein layer called the tegument...

and sometimes a few enzymes stored in a capsule made of protein (called a capsid), and sometimes covered with a lipid layer (sometimes called an 'envelope')...

different depending on the type of virus it is. A virus with a nonenveloped capsid enters the cell by attaching to the attachment factor located on a host...

assembly of infectious virus particles. HIV assembly is a two-stage process involving an intermediate immature capsid that undergoes a structurally dramatic...

of the HIV and increase the efficacy of the drug. Galectin-3 binds TRIM5α, a cytosolic restriction factor against HIV acting during HIV capsid uncoating...

the mature capsid lattice. These studies identify IP6 as a naturally occurring small molecule that promotes both assembly and maturation of HIV-1. IP6 has...

Wire, where he is an associate editor. His 2016 book Capsid: A Love Song won the POZ Award for best HIV writing (fiction/poetry) and was a finalist for a...

viral infection, NAbs can bind to glycoproteins of enveloped viruses or capsid proteins of non-enveloped viruses. Furthermore, neutralizing antibodies...

over the course of one month. The attachment and inhibition of HIV reverse transcriptase by DPV prevent HIV genome replication within the host upon initial...

PMID 2737204. Göttlinger HG, Sodroski JG, Haseltine WA (1989). "Role of capsid precursor processing and myristoylation in morphogenesis and infectivity...

Meister G, Landthaler M, Dorsett Y, Tuschl T (Mar 2004). "Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing". RNA. 10 (3): 544–50. doi:10...

icosahedral nucleocapsid and it has function in replication of the virus. Capsid formation is the main factor for infection of the cell. HBcAg contributes...

FightAIDS@home paper on the discovery of new vulnerabilities on the HIV-1 Capsid protein which may allow for a new drug target; a FightAIDS@home paper...

virus in vitro. Fusion between the viral envelope (surrounding the viral capsid) and the cell membrane of the target cell is inhibited. This prevents viral...

lipids and forming ion channels in the inner capsid with experimental evidence showing inhibition of HIV and HSV. However, surfactin can only degrade...

calmodulin-binding protein - Calvin cycle - CAM photosynthesis - CAM plants - cancer - capsid - carbohydrate - carbon - carbon fixation - carboxylic acid - carcinoembryonic...

cellular membrane, releasing tegument proteins and the naked capsid into the cytoplasm. The capsid travels to a nuclear pore, likely along cytoskeletal microtubules...

composed of five expression units: from the N terminal to the C terminal - Capsid, E3, E2, 6K and E1. A sub genomic positive strand RNA - the 26S RNA - is...

alternative reading frame of the P-coding mRNA, is also associated with a viral capsid. It is present in SeV virions at relatively low levels (40 molecules/genome)...

Multiple integrin heterodimers can bind to the adjacent sites of the virus capsid. Similar to SV40, attachment and binding with cells triggers clustering...