Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease...
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Paracetamol poisoning (redirect from Acetaminophen hepatotoxicity)
inducer isoniazid increases the risk of hepatotoxicity, though whether 2E1 induction is related to the hepatotoxicity in this case is unclear. Concomitant...
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addition to the kava lactones is important to provide protection against hepatotoxicity". It has also been argued that kavalactone extracts have often been...
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published in the World Journal of Hepatology reexamined known cases of hepatotoxicity that had previously been linked to consumption of Herbalife products...
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Cholestasis (redirect from Cholestatic hepatotoxicity)
Cholestasis is a condition where the flow of bile from the liver to the duodenum is impaired. The two basic distinctions are: obstructive type of cholestasis...
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Troglitazone (section Mechanisms of hepatotoxicity)
$136 million. Since the withdrawal in 2000, mechanisms of troglitazone hepatotoxicity have been extensively studied using a variety of in vivo, in vitro,...
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hepatotoxicity; however, an increasing number of subsequent case reports suggested that some individuals may be particularly sensitive to hepatotoxic...
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for hepatotoxicity during drug metabolism with a number of different drugs, including flucloxacillin, troleandomycin, and troglitazone. Hepatotoxicity indicates...
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Auclert, L; Le-Louët, H (November 2021). "Safety data and withdrawal of hepatotoxic drugs". Therapie. 76 (6): 715–723. doi:10.1016/j.therap.2018.02.004....
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the 1950s and 1960s. Most have been withdrawn due to toxicity, namely hepatotoxicity, but a few still remain in clinical use. Tranylcypromine, a structurally...
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organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). Sometimes the word is more or less synonymous with poisoning in everyday...
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(US) Malignancies, injection site reactions, blood clots, lymphopenia, hepatotoxicity and infections. Azathioprine Purine analogue that inhibits lymphocyte...
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fatal or non-fatal strokes. Prescription niacin was shown to cause hepatotoxicity and increase risk of type 2 diabetes. Niacin prescriptions in the U...
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Nicotine gum (section Hepatotoxicity)
Nicotine gum is a chewing gum containing the active ingredient nicotine polacrilex. It is a type of nicotine replacement therapy (NRT) used alone or in...
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Rosiglitazone (section Hepatotoxicity)
Rosiglitazone (trade name Avandia) is an antidiabetic drug in the thiazolidinedione class. It works as an insulin sensitizer, by binding to the PPAR in...
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stenosis. Erythromycin estolate has been associated with reversible hepatotoxicity in pregnant women in the form of elevated serum glutamic-oxaloacetic...
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and 17%), with hepatotoxicity. In contrast, testosterone esters have only extremely rarely or never been associated with hepatotoxicity, and other non-17α-alkylated...
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CIOMS/RUCAM scale (section Hepatotoxicity)
liver damage can be attributed to a particular medication. Determining hepatotoxicity (toxic effects of a substance on the liver) remains a major challenge...
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of this uncertainty and the potential for toxicity in the fetus and hepatotoxicity in the mother, valerian use is discouraged during pregnancy. Headache...
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degradation. Studies in mice have found the following health effects: Hepatotoxicity, developmental toxicity, immunotoxicity, hormonal effects and carcinogenic...
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Zafirlukast (section Hepatotoxicity)
but serious side effects like acute liver injury. Zafirlukast-induced hepatotoxicity generally occurs within the first 2–6 months of initiating therapy,...
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analogue, male-limited precocious puberty. In any case, the risk of hepatotoxicity with ketoconazole limits its use in all of these indications, especially...
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half-life is more than 4 hours, then treatment is necessary to prevent hepatotoxicity and liver failure. The original line, sometimes referred to as the Rumack–Matthew...
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through use of probe drugs to measure inhibition. Its anxiolytic and hepatotoxicity activities have been investigated. The major kavalactones (except for...
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fluid retention. Drostanolone propionate is not known to pose a risk of hepatotoxicity. Drostanolone propionate is a prodrug of drostanolone. Like other AAS...
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risk of liver toxicity, including liver failure. Despite its risk of hepatotoxicity, a 2012 evaluation by the European Medicines Agency (EMA) concluded...
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many[who?] valued oxandrolone's supposed[clarification needed] low hepatotoxicity relative to most other orally active AASs. Like other AASs, oxandrolone...
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indicators, such as serum transaminase (AST/ALT) levels, to confirm hepatotoxicity. Although unlikely, it is impossible to rule out that methocarbamol...
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volatile yellow oil. NDMA has attracted wide attention as being highly hepatotoxic and a known carcinogen in laboratory animals. Of more general concern...
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potential interaction has been reported with imatinib, resulting in hepatotoxicity, and with lamotrigine. The common ginsengs (P. ginseng and P. quinquefolia)...
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