Immunohistochemistry is a form of immunostaining. It involves the process of selectively identifying antigens (proteins) in cells and tissue, by exploiting...
33 KB (3,561 words) - 06:08, 30 October 2024
The immunohistochemistry (IHC) test is a laboratory method that detects antibodies of prions (mis-shapen proteins thought to transmit bovine spongiform...
2 KB (216 words) - 14:36, 31 May 2024
compartments are expressing the antigen. Immunocytochemistry differs from immunohistochemistry in that the former is performed on samples of intact cells that have...
7 KB (924 words) - 16:17, 24 October 2023
AE1/AE3 is an antibody cocktail that is used in immunohistochemistry, being generally positive in the cytoplasm of carcinomas (cancers of epithelial origin)...
3 KB (208 words) - 22:24, 11 December 2023
Immunostaining (section Immunohistochemistry)
and molecular biology that use antibody-based staining methods. Immunohistochemistry or IHC staining of tissue sections (or immunocytochemistry, which...
11 KB (1,299 words) - 12:34, 3 September 2024
HER2 (section Immunohistochemistry)
needle biopsy, vacuum-assisted breast biopsy, or surgical excision. Immunohistochemistry (IHC) is generally used to measure the amount of HER2 protein present...
43 KB (4,651 words) - 13:41, 27 July 2024
Angela Felicia; Tan, Sukmawati Tansil (2017). "The Use of BEREP4 Immunohistochemistry Staining for Detection of Basal Cell Carcinoma". Journal of Skin...
3 KB (210 words) - 23:22, 15 December 2021
The diagnosis of ICCB tumors is based on the histopathology and immunohistochemistry of their hematoxylin and eosin-stained tissues, particularly on identifying...
23 KB (2,794 words) - 00:41, 3 December 2023
Histology (section Immunohistochemistry)
embedding media, but acrylic resins are also used, particularly where immunohistochemistry is required. For tissues to be cut in a frozen state, tissues are...
33 KB (3,193 words) - 04:44, 16 November 2024
Mammary secretory carcinoma (MSC), also termed secretory carcinoma of the breast, is a rare form of the breast cancers. MSC usually affects women but in...
26 KB (3,130 words) - 14:59, 15 October 2024
CD31 (section Immunohistochemistry)
cells, B cells, and NK cells), megakaryocytes, and osteoclasts. In immunohistochemistry, CD31 is used primarily to demonstrate the presence of endothelial...
26 KB (3,115 words) - 07:13, 15 October 2024
Hyperplastic polyp (section Immunohistochemistry)
where nuclei are enlarged, the nucleus/cytoplasm ratio is elevated. Immunohistochemistry using Ki-67 stains the basal 1⁄3 to 1⁄2 of crypts, indicating a proliferative...
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molecular markers are characteristic of particular cancer types. Immunohistochemistry is also widely used in basic research to understand the distribution...
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Pseudomyxoma peritonei (section Immunohistochemistry)
Pseudomyxoma peritonei (PMP) is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that produce abundant mucin or gelatinous ascites...
20 KB (2,340 words) - 13:51, 31 October 2024
"Histology and Prognosis". Rudin et al. 2021, "Immunohistochemistry". Horn & Iams 2022, "Immunohistochemistry". Lim et al. 2018, "Table 5: Overall stage based...
90 KB (9,784 words) - 07:53, 10 October 2024
Complement receptor 2 (section Immunohistochemistry)
dendritic cells (FDCs), this becomes readily apparent only when immunohistochemistry is performed on frozen sections. In more conventional paraffin-embedded...
14 KB (1,829 words) - 12:12, 6 October 2024
Methods commonly used to study protein structure and function include immunohistochemistry, site-directed mutagenesis, X-ray crystallography, nuclear magnetic...
103 KB (11,472 words) - 16:37, 31 October 2024
In cases where a metastasis from colorectal cancer is suspected, immunohistochemistry is used to ascertain correct diagnosis. Some proteins are more specifically...
20 KB (2,114 words) - 01:56, 28 July 2024
CD5 (protein) (section Immunohistochemistry)
CD5 is a cluster of differentiation expressed on the surface of T cells (various species) and in a subset of murine B cells known as B-1a. The expression...
12 KB (1,476 words) - 07:15, 15 October 2024
in the tissue (immunohistochemistry); or extraction of the protein and identification of its individual amino acids. Immunohistochemistry can identify AA...
55 KB (5,423 words) - 03:20, 19 October 2024
processing steps and final analyses that are planned. For example, immunohistochemistry uses antibodies that bind to a specific protein target. Prolonged...
19 KB (2,387 words) - 06:19, 26 November 2023
Nasal glial heterotopia (section Immunohistochemistry)
Nasal glial heterotopia refers to congenital malformations of displaced normal, mature glial tissue, which are no longer in continuity with an intracranial...
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and immunohistochemistry. Because BSA is a small, stable, moderately non-reactive protein, it is often used as a blocker in immunohistochemistry. During...
15 KB (1,488 words) - 21:52, 8 November 2024
Clinical Criteria and Bethesda Guidelines, or through tumor analysis by immunohistochemistry (IHC), or microsatellite instability (MSI) testing. In the US, professional...
48 KB (4,986 words) - 00:50, 22 November 2024
antibodies associated with typhus. It can also be done with either immunohistochemistry (IHC) or polymerase chain reaction (PCR) tests excluding scrub typhus...
34 KB (3,477 words) - 05:13, 21 November 2024
(2011). "Head and neck squamous cell carcinoma: mismatch repair immunohistochemistry and promoter hypermethylation of hMLH1 gene". Am J Otolaryngol. 32...
51 KB (5,895 words) - 11:54, 2 November 2024
CD3 (immunology) (section Immunohistochemistry)
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells)...
7 KB (757 words) - 08:44, 5 May 2024
Inflammatory Linear Verrucous Epidermal Nevus is a rare disease of the skin that presents as multiple, discrete, red papules that tend to coalesce into...
9 KB (1,020 words) - 19:57, 3 December 2023
Hibernoma (section Immunohistochemistry)
A hibernoma is a benign neoplasm of vestigial brown fat. They were first described under the name ‘pseudolipoma’ by the German physician H. Merkel in 1906...
7 KB (716 words) - 16:35, 7 July 2024
Kidney cancer (section Immunohistochemistry)
Typical immunohistochemistry for various kidney cancer types. PAX8 CD10 CAIX RCC Melanocytic markers Vimentin CK7 HMWCK CD117 / KIT AMACR GATA3 Clear cell...
56 KB (5,187 words) - 09:51, 17 November 2024