Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene....
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The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon...
8 KB (870 words) - 23:14, 28 May 2024
heterodimeric receptor consisting of Interferon gamma receptor 1 (IFNGR1) and Interferon gamma receptor 2 (IFNGR2). IFN-γ binding to the receptor activates...
56 KB (6,476 words) - 11:26, 29 July 2024
Interferon gamma receptor 2 also known as IFN-γR2 is a protein which in humans is encoded by the IFNGR2 gene. This gene (IFNGR2) encodes the non-ligand-binding...
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biology, the interferon gamma receptor (IFNGR1) family is a family of proteins which includes several eukaryotic and viral interferon gamma receptor proteins...
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Mendelian susceptibility to mycobacterial disease (redirect from Interferon gamma, receptor 1, deficiency)
complete deficiency in the interferon-gamma receptor have significant elevations in plasma concentrations of interferon-gamma, which can be measured by...
14 KB (1,413 words) - 03:44, 11 October 2023
interferon-alpha/beta receptor interferon-gamma receptor Interferon type III receptor Interleukin-10 receptor Interleukin-20 receptor Interleukin-22 receptor Interleukin-28...
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The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...
24 KB (2,617 words) - 19:43, 7 August 2022
lymphocytes. Immune interferon (IFN-gamma; MIM 147570) is produced by mitogen- or antigen-stimulated T lymphocytes.[supplied by OMIM] The interferons (IFN)s are...
24 KB (2,894 words) - 01:36, 26 August 2023
Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, interleukin-28 A (Interferon lambda 1), Interleukin-28B...
10 KB (1,126 words) - 20:57, 24 June 2021
nigricans, type A Intercellular cholesterol esterification disease Interferon gamma, receptor 1, deficiency Internal carotid agenesis Intraocular lymphoma Interstitial...
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pseudogenes. Interferons bind to interferon receptors. All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor (IFNAR)...
24 KB (2,932 words) - 03:26, 14 June 2024
proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear receptor subfamily 1, group...
19 KB (2,091 words) - 05:22, 13 July 2024
Based on the type of receptor through which they signal, human interferons have been classified into three major types. Interferon type I: All type I IFNs...
62 KB (7,065 words) - 05:17, 28 June 2024
Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
7 KB (654 words) - 21:00, 23 April 2024
It interacts with the common gamma chain (γc) of type I cytokine receptors, to elicit signals from the IL-2 receptor family (e.g. IL-2R, IL-7R, IL-9R...
21 KB (2,423 words) - 03:55, 27 January 2024
Retinoic acid receptor gamma (RAR-γ), also known as NR1B3 (nuclear receptor subfamily 1, group B, member 3) is a nuclear receptor encoded by the RARG...
10 KB (1,208 words) - 06:34, 8 November 2023
of interferon gamma (IFN-γ). It is a pro-inflammatory cytokine that shares similar biological effects to IL-12 and structural forms with the IL-1 family...
49 KB (6,005 words) - 16:30, 10 June 2024
Cell-mediated immunity (redirect from Type 1 immunity)
TH17 upon IL-1 or IL-23 exposure. Type 1 immunity makes use of the type 1 subset for each of these cell types. By secreting interferon gamma and TNF, TH1...
14 KB (1,381 words) - 03:19, 4 May 2024
problems. Interleukin 12 receptor, beta 1 deficiency IL-12p40 deficiency Interferon gamma receptor 1 deficiency Interferon gamma receptor 2 deficiency Tyk2 deficiency...
19 KB (1,836 words) - 09:52, 5 July 2024
Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...
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Interleukin 12 (redirect from IL-12 and IL-12 Receptor β1 Mutations)
the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural...
14 KB (1,578 words) - 14:00, 26 February 2024
Nishikawa H, et al. (February 2003). "Involvement of Toll-like receptor 4 signaling in interferon-gamma production and antitumor effect by streptococcal agent...
75 KB (9,082 words) - 10:46, 12 June 2024
RIG-I (category RIG-I-like receptors)
gene I) is a cytosolic pattern recognition receptor (PRR) that can mediate induction of a type-I interferon (IFN1) response. RIG-I is an essential molecule...
23 KB (2,831 words) - 13:19, 24 May 2024
Interleukin 10 (category Genes on human chromosome 1)
IL-22, IL-24 (Mda-7), IL-26 and interferons type-I (IFN-alpha, -beta, -epsilon, -kappa, -omega), type-II (IFN-gamma) and type-III (IFN-lambda, including...
40 KB (4,858 words) - 14:50, 21 July 2024
IL-2Rβ, or CD122), and γ (gamma) (also called IL-2Rγ, γc, common gamma chain, or CD132); these subunits are also parts of receptors for other cytokines.: 713 ...
9 KB (934 words) - 09:24, 27 March 2022
Interleukin 18 (section Receptor and signaling)
Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene. The protein encoded by...
18 KB (2,082 words) - 08:54, 18 March 2024
C-X-C motif chemokine ligand 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is an 8.7 kDa protein...
10 KB (1,231 words) - 22:00, 8 March 2024
IRS2 (redirect from Insulin receptor substrate 2)
Carter-Su C (November 1996). "Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling"...
12 KB (1,479 words) - 01:31, 28 November 2023
Interferon-alpha/beta receptor Interferon-gamma receptor Interferon-γ receptor 1 and 2 mutations Interleukin Interleukin 1 family Interleukin 1 receptor antagonist...
13 KB (1,237 words) - 01:24, 15 January 2024