• Thumbnail for Keratinocyte
    Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells...
    25 KB (2,752 words) - 22:34, 25 April 2024
  • Keratinocyte carcinomas are a group of nonmelanoma skin cancers arising from the keratinocyte found in the epidermis of the human skin, namely: Basal-cell...
    2 KB (143 words) - 05:04, 17 August 2024
  • The keratinocyte growth factor (KGF), also known as FGF7, is a growth factor present in the epithelialization-phase of wound healing. In this phase, keratinocytes...
    2 KB (182 words) - 00:56, 11 June 2023
  • Thumbnail for Keratinocyte transglutaminase
    transglutaminase enzyme that in humans is encoded by the TGM1 gene. Keratinocyte transglutaminase enzymes serve to specifically catalyze the development...
    13 KB (1,560 words) - 19:42, 3 December 2023
  • Thumbnail for Epidermis
    epidermis is termed epidermal. The epidermis primarily consists of keratinocytes (proliferating basal and differentiated suprabasal), which comprise...
    28 KB (3,071 words) - 17:12, 14 July 2024
  • Thumbnail for Stratum basale
    to divide and produce new cells, and these are sometimes called basal keratinocyte stem cells. Others serve to anchor the epidermis glabrous skin (hairless)...
    4 KB (383 words) - 11:23, 30 August 2024
  • Thumbnail for Wound healing
    migration. Thus keratinocytes detach from the basement membrane and are able to enter the wound bed. Before they begin migrating, keratinocytes change shape...
    104 KB (11,855 words) - 10:20, 17 August 2024
  • HaCaT is a spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin, widely used in scientific research. HaCaT cells are...
    3 KB (323 words) - 04:10, 24 June 2023
  • Thumbnail for Adapalene
    be used in combination with benzoyl peroxide. Due to its effects on keratinocyte proliferation and differentiation, adapalene is superior to tretinoin...
    19 KB (1,765 words) - 12:36, 3 September 2024
  • Thumbnail for Keratosis
    growth of keratin on the skin or on mucous membranes stemming from keratinocytes, the prominent cell type in the epidermis. More specifically, it can...
    2 KB (84 words) - 03:07, 13 August 2024
  • Thumbnail for Keratin
    whales are also made of keratin. Keratin filaments are abundant in keratinocytes in the hornified layer of the epidermis; these are proteins which have...
    39 KB (3,017 words) - 13:44, 1 September 2024
  • Thumbnail for Desquamation
    scales off a fish'. Keratinocytes are the predominant cells of the epidermis, the outermost layer of the skin. Living keratinocytes reside in the basal...
    9 KB (878 words) - 21:05, 24 July 2024
  • Thumbnail for Hemidesmosome
    Hemidesmosomes are very small stud-like structures found in keratinocytes of the epidermis of skin that attach to the extracellular matrix. They are similar...
    8 KB (866 words) - 05:33, 1 September 2024
  • Thumbnail for FGF7
    Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. The protein encoded by this gene is a member of the fibroblast growth...
    10 KB (1,231 words) - 00:45, 6 June 2024
  • Thumbnail for Melanocyte
    special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes...
    20 KB (2,274 words) - 09:10, 28 July 2024
  • Thumbnail for Minoxidil
    Antiandrogen: A Study of 5α-reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line" (PDF). Acta Dermatovenerologica Croatica. 25 (4): 271–275...
    47 KB (4,450 words) - 03:55, 29 August 2024
  • Thumbnail for Acanthosis nigricans
    insulin-like growth factor receptors, which leads to proliferation of keratinocytes, fibroblasts and other cells in the skin. Activation of other growth...
    18 KB (1,782 words) - 19:54, 17 July 2024
  • Thumbnail for Skin
    composed of proliferating basal and differentiated suprabasal keratinocytes. Keratinocytes are the major cells, constituting 95% of the epidermis, while...
    36 KB (4,279 words) - 13:28, 8 August 2024
  • Thumbnail for Bullous pemphigoid
    involves formation of anti-hemidesmosome antibodies, causing a loss of keratinocytes to basement membrane adhesion. Clinically, the earliest lesions may...
    13 KB (1,322 words) - 06:46, 2 September 2024
  • Thumbnail for Harlequin-type ichthyosis
    across cell membranes. ABCA12 is thought to be a lipid transporter in keratinocytes necessary for lipid transport into lamellar granules during the formation...
    32 KB (3,105 words) - 10:34, 15 July 2024
  • Corneocytes are terminally differentiated keratinocytes and compose most of the stratum corneum, the outermost layer of the epidermis. They are regularly...
    20 KB (2,272 words) - 23:08, 30 April 2024
  • Thumbnail for Stratum spinosum
    granulosum and stratum basale. This layer is composed of polyhedral keratinocytes. These are joined with desmosomes. Their spiny (Latin, spinosum) appearance...
    4 KB (442 words) - 19:00, 3 September 2024
  • Thumbnail for Integumentary system
    epithelium; four types of cells: keratinocytes, melanocytes, Merkel cells, and Langerhans cells. The predominant cell keratinocyte, which produces keratin, a...
    12 KB (1,355 words) - 15:20, 14 August 2024
  • Thumbnail for Sandalore
    induce strong Ca2+ signals in cultured human keratinocytes. The long-term stimulation of keratinocytes with Sandalore positively affected cell proliferation...
    3 KB (197 words) - 16:59, 3 January 2023
  • Thumbnail for Papillomaviridae
    icosahedral surface lattice. Papillomaviruses replicate exclusively in keratinocytes. Keratinocytes form the outermost layers of the skin, as well as some mucosal...
    63 KB (7,242 words) - 05:09, 15 April 2024
  • Thumbnail for Stratum lucidum
    it is composed of three to five layers of dead, flattened keratinocytes. The keratinocytes of the stratum lucidum do not feature distinct boundaries and...
    2 KB (245 words) - 17:17, 9 March 2024
  • Thumbnail for Squamous-cell carcinoma
    are flat cells that line many areas of the body. Some of which are keratinocytes. Accumulation of these cancer cells causes a microscopic focus of abnormal...
    21 KB (2,236 words) - 06:17, 5 August 2024
  • Thumbnail for Skin whitening
    that reach keratinocytes. Melanosomes, along with the melanin they contain, are transferred from melanocytes to keratinocytes when keratinocytes are low...
    66 KB (7,543 words) - 16:38, 14 August 2024
  • Thumbnail for Vitamin D
    dermis, and the outer, thinner epidermis. Vitamin D is produced in the keratinocytes of two innermost strata of the epidermis, the stratum basale and stratum...
    163 KB (17,848 words) - 11:10, 1 September 2024
  • Thumbnail for Sebaceous gland
    cross section showing hair follicle with sebaceous glands. Relative to keratinocytes that make up the hair follicle, sebaceous glands are composed of huge...
    29 KB (3,377 words) - 15:16, 1 September 2024