The latrunculins are a family of natural products and toxins produced by certain sponges, including genus Latrunculia and Negombata, whence the name is...
27 KB (2,852 words) - 06:38, 3 June 2024
these drugs have multiple effects on the cytoskeleton: for example, Latrunculin both prevents actin polymerization as well as enhancing its rate of depolymerization...
10 KB (1,078 words) - 15:20, 11 November 2022
(28 in). Negombata magnifica is extremely toxic because of the toxin latrunculin. Negombata magnifica lives on shallow coral reefs in the northern waters...
2 KB (159 words) - 22:01, 6 November 2023
dynamics are widely used in research to study actin's role in biology. Latrunculin – a toxin produced by sponges – binds to G-actin preventing it from joining...
151 KB (18,106 words) - 19:32, 11 July 2024
maintenance of cell polarity revealed using the actin inhibitor latrunculin-A Latrunculin alters the actin-monomer subunit interface to prevent polymerization...
7 KB (661 words) - 15:29, 27 September 2023
RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1 1esv: COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 1h1v: GELSOLIN G4-G6/ACTIN...
8 KB (997 words) - 22:28, 15 April 2024
x. PMID 19686371. Gibbon BC, Kovar DR, Staiger CJ (December 1999). "Latrunculin B has different effects on pollen germination and tube growth". The Plant...
48 KB (6,442 words) - 08:17, 9 June 2024
maintenance of cell polarity while using and popularizing the actin inhibitor latrunculin-A. He established that cofilin is largely responsible for actin filament...
14 KB (1,434 words) - 22:06, 12 October 2023
1021/jo00019a004. James D. White, Motoji Kawasaki: "Total synthesis of (+)-latrunculin A", in: J. Am. Chem. Soc., 1990, 112, pp. 4991–4993; doi:10.1021/ja00168a071...
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"Total Syntheses of the Actin-Binding Macrolides Latrunculin A, B, C, M, S and 16-epi-Latrunculin B". Chem. Eur. J. 13 (1): 115–134. doi:10.1002/chem...
13 KB (1,309 words) - 02:51, 30 November 2023
leaving this polymer which causes the stabilization of the molecule. Latrunculin is similar to cytochalasin, but it is a toxin which will bind to the...
14 KB (1,806 words) - 21:19, 11 November 2023
1021/jo0610053 Diverted total synthesis: Preparation of a focused library of latrunculin analogues and evaluation of their actin-binding properties Alois Fürstner...
6 KB (619 words) - 19:44, 27 October 2022
it impacted TNT formation without the destruction of existing TNTs. Latrunculin-B, another F-actin depolymerizing compound, was found to completely block...
31 KB (3,391 words) - 02:59, 16 December 2023
checkered board. The Romans played a derivation of 'petteia' called 'latrunculin' or Ludus latrunculorum (the soldiers' game or the bandits' game). It...
67 KB (8,549 words) - 04:06, 18 July 2024
protein was similar to IZUMO1 and is considered to be an inhibitor of latrunculin. In 2011 he and his colleagues presented strong evidence of transmembrane...
3 KB (320 words) - 17:25, 23 August 2023
RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1 1esv: COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 1h1v: GELSOLIN G4-G6/ACTIN...
14 KB (1,645 words) - 10:13, 4 January 2024
RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1 1esv: COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 1h1v: GELSOLIN G4-G6/ACTIN...
9 KB (1,136 words) - 03:07, 6 May 2024
RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1 1esv: COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 1h1v: GELSOLIN G4-G6/ACTIN...
24 KB (2,991 words) - 01:53, 1 December 2023
RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1 1esv: COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 1h1v: GELSOLIN G4-G6/ACTIN...
12 KB (1,505 words) - 23:50, 8 April 2024
receptor activation is required for this effect. Furthermore, the use of latrunculin A was able to impair late phase LTP in this model, again suggesting that...
21 KB (2,558 words) - 13:40, 29 January 2023
of CD were found to be needed to remove stress fibers. In contrast, latrunculin inhibits actin filament polymerization by binding to actin monomers....
8 KB (900 words) - 03:42, 28 June 2024
and memory. Experiments have shown that drugs like cytochalasin C and Latrunculin A that inhibit the assembly of G-actin into F-actin disrupt both the...
11 KB (1,629 words) - 16:36, 1 November 2022
diverse array of chemical compounds found in its species, including the latrunculins, which are named after this genus. Many of these are medically important...
8 KB (545 words) - 06:45, 8 November 2023
and microtubules. Furthermore, anillin-rich structures that form after Latrunculin A treatment of Drosophila cells localize to the plus-ends of microtubules...
23 KB (2,939 words) - 07:48, 17 July 2024
These small molecules include the actin inhibitors, jasplakinolide and latrunculin, the Mitochondrial Complex I inhibitor, mycothiazole, the human methionine...
15 KB (1,434 words) - 19:05, 23 January 2024
RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1 1esv: COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 1h1v: GELSOLIN G4-G6/ACTIN...
16 KB (2,007 words) - 03:28, 6 May 2024
RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1 1esv: COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 1h1v: GELSOLIN G4-G6/ACTIN...
8 KB (1,017 words) - 02:24, 6 May 2024