• Leuckart reaction is the chemical reaction that converts aldehydes or ketones to amines by reductive amination in the presence of heat. The reaction,...
    6 KB (635 words) - 05:39, 24 May 2024
  • The Leuckart thiophenol reaction is the decomposition of a diazoxanthate, by gentle warming in a slightly acidic cuprous medium, to its corresponding aryl...
    2 KB (128 words) - 08:43, 13 August 2020
  • Thumbnail for Eschweiler–Clarke reaction
    this reaction replace formic acid with sodium cyanoborohydride. Leuckart–Wallach reaction Pictet–Spengler reaction Moore, M. L. (1949). "The Leuckart Reaction"...
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  • reaction Leimgruber–Batcho indole synthesis Letts nitrile synthesis Leuckart reaction Leuckart thiophenol reaction Leuckart–Wallach reaction Leuckart...
    37 KB (3,428 words) - 16:27, 11 November 2024
  • Thumbnail for Methamphetamine
    starting from phenylacetone by either the Leuckart or reductive amination methods. In the Leuckart reaction, one equivalent of phenylacetone is reacted...
    156 KB (15,400 words) - 03:45, 20 November 2024
  • Thumbnail for Benzylamine
    accidentally by Rudolf Leuckart in the reaction of benzaldehyde with formamide in a process now known as the Leuckart reaction, a general process in which...
    15 KB (1,193 words) - 02:21, 9 September 2024
  • Thumbnail for Amphetamine
    synthesis employs a non-metal reduction known as the Leuckart reaction (method 1). In the first step, a reaction between phenylacetone and formamide, either using...
    274 KB (28,856 words) - 21:41, 23 November 2024
  • This reaction is related to the Eschweiler–Clarke reaction, in which amines are methylated to tertiary amines, the Leuckart–Wallach reaction, or by...
    21 KB (2,128 words) - 04:09, 19 November 2024
  • Thumbnail for Formamide
    Formamide (section Reactions)
    amines directly from ketones via their N-formyl derivatives, using the Leuckart reaction. Formamides are intermediates in the methanogenesis cycle. Formamide...
    10 KB (901 words) - 10:48, 4 October 2024
  • Thumbnail for Amine
    Amine (section Reactions)
    {\displaystyle {\ce {ROH + NH3 -> RNH2 + H2O}}} Unlike the reaction of amines with alcohols the reaction of amines and ammonia with alkyl halides is used for...
    36 KB (3,783 words) - 03:26, 25 November 2024
  • Thumbnail for Ammonium formate
    used for reductive amination of aldehydes and ketones (Leuckart reaction), by the following reaction: Ammonium formate can be used as a mobile phase additive...
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  • Thumbnail for Formetorex
    is also an intermediate in the production of amphetamine by the "Leuckart reaction." It is also commonly found as an impurity in clandestine labs where...
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  • Thumbnail for Abemaciclib
    amination with the final step being a reductive amination using the Leuckart reaction. "Verzenio (Eli Lilly Australia Pty Ltd)". Therapeutic Goods Administration...
    18 KB (1,467 words) - 23:44, 20 August 2024
  • Thumbnail for 1-Phenylethylamine
    of acetophenone: C6H5C(O)CH3 + NH3 + H2 → C6H5CH(NH2)CH3 + H2O The Leuckart reaction, using ammonium formate, is another method for this transformation...
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  • Alexander Leuckart (23 June 1854 – 24 July 1889) was a German chemist who discovered the Leuckart reaction and Leuckart thiophenol reaction. He was the...
    2 KB (94 words) - 00:21, 12 June 2023
  • Secondary and tertiary amines may also be produced by the Leuckart reaction. This reaction effects N-methylation using formaldehyde with formic acid as...
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  • Thumbnail for Formic acid
    in the Eschweiler–Clarke reaction: It is used as a source of hydrogen in transfer hydrogenation, as in the Leuckart reaction to make amines, and (in aqueous...
    38 KB (3,856 words) - 17:07, 1 November 2024
  • Thumbnail for 3,4-Methylenedioxyamphetamine
    by J. Elks, et al. This gives MDP2P, which was then subjected to a Leuckart reaction. The "two dogs" or "dopeboy" clandestine method, starting with helional...
    25 KB (2,330 words) - 00:54, 13 November 2024
  • Thumbnail for Thiophenol
    by heating to give the isomeric S-aryl derivative (4). In the Leuckart thiophenol reaction, the starting material is an aniline through the diazonium salt...
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  • Thumbnail for Amide
    Amide (redirect from Bodroux reaction)
    (1966). Advanced organic Chemistry, Reactions, mechanisms and structure (3rd ed.). Wiley. ISBN 978-0-471-85472-2. Leuckart, R. (1885). "Ueber einige Reaktionen...
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  • Thumbnail for Otto Wallach
    Wallach's rule, Wallach degradation, the Leuckart-Wallach reaction (which he developed along with Rudolf Leuckart) and the Wallach rearrangement.[citation...
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  • Thumbnail for 4-Methylthioamphetamine
    has been prepared from 4-(methylthio)phenylacetone by the Leuckart reaction and the reaction byproducts have been characterized. 4-MTA undergoes limited...
    18 KB (1,888 words) - 08:47, 21 November 2023
  • Thumbnail for Ephenidine
    "Analgesics; n-alkylated-1,2-diphenylethylamines prepared by the Leuckart reaction". Journal of the American Chemical Society. 68 (11): 2174–2175. doi:10...
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  • Thumbnail for Aplysia
    (mtDNA) sequence data of ribosomal genes (rDNA). Aplysia argus Rüppell & Leuckart, 1830 Aplysia atromarginata Bergh, 1905 Aplysia brasiliana Rang, 1828 Aplysia...
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  • Thumbnail for Onchocerciasis
    skin disease along the west coast of Africa, known as "craw-craw". Rudolf Leuckart, a German zoologist, later examined specimens of the same filarial worm...
    61 KB (6,695 words) - 20:52, 15 November 2024
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    "Antiarrhythmic piperazine derivs prepn - from benzhydrylpiperazine cinnamaldehyde by leuckart reaction", issued 1972, assigned to Hokuriku Pharmaceutical ...
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  • Thumbnail for Thiol
    Thiol (section Reactions)
    Synlett. 23 (13): 1893–1896. doi:10.1055/s-0032-1316557. S2CID 196805424. Leuckart, Rudolf (1890). "Eine neue Methode zur Darstellung aromatischer Mercaptane"...
    35 KB (3,886 words) - 02:58, 4 July 2024
  • order to isolate the more active dextromethamphetamine. The alternative Leuckart route also relies on P2P to produce a racemic product, but proceeds via...
    93 KB (10,133 words) - 04:53, 25 November 2024
  • Thumbnail for Ludwig Gattermann
    chemists worked as assistants in his group, which consisted of Rudolf Leuckart, Emil Knoevenagel, Traugott Sandmeyer and Karl von Auwers. His private...
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  • Thumbnail for Dracunculiasis
    based on his observations of many waterborne animals. However, Rudolf Leuckart claimed that he had advised Fedchenko to investigate Cyclops copepods due...
    41 KB (4,530 words) - 00:46, 22 November 2024