Malignant transformation is the process by which cells acquire the properties of cancer. This may occur as a primary process in normal tissue, or secondarily...

become malignant (grade 3), and malignant pure teratomas have the potential to metastasize. These rare forms of teratoma with malignant transformation may...

of these Mycoplasma species have shown a strong correlation to malignant transformation in mammalian cells in vitro. The presence of Mycoplasma was first...

able to assist the formation of malignant tumours due to a mechanism of cell transformation. This cell transformation can occur through either "DNA integration...

itching, pain, and disfigurement.[citation needed] No evidence of malignant transformation has been found. Plexiform neurofibromas can grow from nerves in...

suppressor genes are genes that inhibit cell division and survival. Malignant transformation can occur through the formation of novel oncogenes, the inappropriate...

initiation and promotion. The molecular mechanisms underlying the malignant transformation of normal mesothelial cells by asbestos fibers remain unclear despite...

research describes the rare occurrence of malignant transformations of these normally benign tumors. Malignant craniopharyngiomas can occur at any age,...

tumors usually do not return. Exceptions to this rule may indicate malignant transformation. Benign tumors are very diverse; they may be asymptomatic or may...

type, and up to one-third are malignant. In males, GCTs of the testis occur typically after puberty and are malignant (testicular cancer). In neonates...

figures or atypical melanocytic cytology are seen, potentially mimicking a malignant melanoma. Evaluation by an expert skin pathologist is advisable in some...

Oral leukoplakia is a potentially malignant disorder affecting the oral mucosa. It is defined as "essentially an oral mucosal white/gray lesion that cannot...

potential risk of malignant transformation.' Per Sharma et al., in 2024 redefined it OSF as “Areca nut-induced potentially malignant disorder of the oral...

painful obstructions (so-called "malignant by location", despite being a benign growth histologically). Malignant transformation of lipomas into liposarcomas...

physical form after birth or hatching Malignant transformation, the process of cells becoming cancerous Transformation (genetics), genetic alteration of a...

of a cancer type where mitotic nondisjunction can contribute to malignant transformation: Mutations of the RB1 gene, which is located on chromosome 13 and...

myeloma is the result of a multi-step malignant transformation, and almost universally originates from the pre-malignant stage monoclonal gammopathy of undetermined...

polyps), which have the potential to progress into cancer (see: Malignant transformation). Premalignant lesions are morphologically atypical tissue which...

point to a possible malignant transformation. Such loss of structural differentiation is especially seen in most, but not all, malignant neoplasms. Sometimes...

thickness decreases with age. A cap more than 2 cm thick, indicates malignant transformation of a tumor. The cartilage cap merges with the epiphyseal area of...

ovarian cancer): Mandal, Shramana; Badhe, Bhawana A. (2012). "Malignant Transformation in a Mature Teratoma with Metastatic Deposits in the Omentum: A...

potential for growth, recurrence, and transformation into malignant melanoma. Because malignant transformation is rare, optic melanocytomas can usually...

intervention, either surgical or medical, lest it lead to cancer via malignant transformation. When cells are faced with physiological or pathological stresses...

visceral cysts and benign tumors with potential for subsequent malignant transformation. It is a type of phakomatosis that results from a mutation in the...

lab (2024 ). These models demonstrate that BRD4-NUT alone drives malignant transformation and spread of NUT carcinoma and will help enable the discovery...

and degradation can lead to pathological conditions, such as malignant transformation, inflammation and tissue injury. Succinic acid is marketed as food...

for WHO grade II have been suggested, but are not established. Malignant transformation of spinal ganglioglioma has been seen in only a select few cases...

have the capacity to grow to large proportions and may undergo malignant transformation, to form carcinoma ex-pleomorphic adenoma, a risk that increases...

FNH and the fact that they rarely progress in size or undergo malignant transformation, FNH tumors are usually managed with clinical monitoring. Surgical...

individuals are at risk for development of sarcomas as a result of malignant transformation. The risk that people with hereditary multiple osteochondromas...