• mannose 6-phosphate receptors (MPRs) are transmembrane glycoproteins that target enzymes to lysosomes in vertebrates. Mannose 6-phosphate receptors bind...
    26 KB (2,963 words) - 06:28, 30 January 2022
  • Thumbnail for Mannose 6-phosphate
    Mannose-6-phosphate (M6P) is a molecule bound by lectin in the immune system. M6P is converted to fructose 6-phosphate by mannose phosphate isomerase...
    4 KB (320 words) - 00:19, 4 August 2023
  • Thumbnail for Cation-dependent mannose-6-phosphate receptor
    biology, the cation-dependent mannose-6-phosphate receptor (CD-MPR) also known as the 46 kDa mannose 6-phosphate receptor is a protein that in humans is...
    10 KB (1,330 words) - 17:41, 16 April 2024
  • Thumbnail for Insulin-like growth factor 2 receptor
    Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
    13 KB (1,664 words) - 16:27, 25 May 2024
  • Thumbnail for Endosome
    the EGF receptor have a pH-resistant bond that persists until it is delivered to lysosomes for their degradation. The mannose 6-phosphate receptor carries...
    22 KB (2,647 words) - 07:14, 29 May 2024
  • 6P (redirect from 6-P)
    6-P may refer to: 6P, IATA code for Club Air 6P/d'Arrest, a periodic comet 6-P, abbreviation for 6-phosphate Mannose 6-phosphate Mannose 6-phosphate receptor...
    962 bytes (165 words) - 16:19, 9 December 2021
  • Thumbnail for Mannose
    hexose-6-phosphate.[citation needed] α-Mannosidase Mannose receptor Mannan oligosaccharide-based nutritional supplements Rhamnose, 6-deoxy-L-mannose PTS...
    17 KB (1,727 words) - 02:40, 16 September 2024
  • Thumbnail for Perilipin-3
    Mannose-6-phosphate receptor binding protein 1 (M6PRBP1) is a protein which in humans is encoded by the M6PRBP1 gene. Its gene product, as well as the...
    11 KB (1,309 words) - 00:27, 24 December 2023
  • Thumbnail for Endocytosis
    lysosomal membrane proteins and active lysosomal hydrolases, but no mannose-6-phosphate receptor. They are generally regarded as the principal hydrolytic compartment...
    25 KB (2,980 words) - 14:58, 19 June 2024
  • Thumbnail for Fibronectin type II domain
    cation-independent mannose-6-phosphate receptor; mannose receptor of macrophages; 180 Kd secretory phospholipase A2 receptor; DEC-205 receptor; 72 Kd and 92...
    7 KB (808 words) - 13:40, 22 March 2023
  • mannose-6-phosphate is accomplished by two proteins: CI-MPR (cation-independent mannose-6-phosphate receptor) and CD-MPR (cation-dependent mannose-6-phosphate...
    26 KB (3,161 words) - 19:09, 8 June 2024
  • from Latin morbilli (measles), parotitis (mumps) and rubella Mannose 6-phosphate receptor, a family of transmembrane proteins that help transport proteins...
    2 KB (311 words) - 06:50, 17 August 2024
  • Thumbnail for Cathepsin F
    may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and...
    8 KB (990 words) - 17:07, 29 May 2024
  • death receptors, and chemotherapy drugs. The main mechanism of trafficking L-SMase to the lysosome is through the mannose 6-phosphate receptor mediated...
    8 KB (878 words) - 23:29, 13 August 2024
  • Thumbnail for Lysosome
    lysosomal tag, mannose 6-phosphate, is added to the peptides. The presence of these tags allow for binding to mannose 6-phosphate receptors in the Golgi...
    43 KB (4,709 words) - 14:32, 4 September 2024
  • Thumbnail for GGA2
    an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal...
    11 KB (1,389 words) - 20:42, 23 December 2023
  • Thumbnail for RABEPK
    p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor (MPR) from endosomes to the trans-Golgi network. RABEPK has been...
    4 KB (503 words) - 02:29, 28 March 2022
  • Thumbnail for GGA3
    an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal...
    9 KB (1,147 words) - 00:25, 23 December 2023
  • Thumbnail for NAGPA
    mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose...
    6 KB (701 words) - 16:46, 28 October 2022
  • Thumbnail for STX10
    has been implicated in endosome to Golgi trafficking of the mannose 6-phosphate receptor and glucose transporter type 4. STX10 has been detected in the...
    4 KB (538 words) - 11:19, 11 December 2023
  • Thumbnail for Retromer
    the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor". The Journal of Cell Biology. 165 (1): 123–133. doi:10.1083/jcb...
    19 KB (1,993 words) - 06:11, 27 May 2024
  • like: Spectrum of Genetic Disorders in Arabs, Lebanese type of mannose 6--phosphate receptor recognition defect (1984), Algerian type of spondylometaphyseal...
    66 KB (6,343 words) - 13:48, 26 September 2024
  • Thumbnail for AP1B1
    Hirokawa N (November 2000). "A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex"...
    9 KB (1,138 words) - 00:14, 5 October 2022
  • Thumbnail for Glucocerebrosidase
    S, Edmunds T, Saftig P (November 2007). "LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase". Cell...
    18 KB (2,001 words) - 01:59, 27 January 2024
  • Thumbnail for Alpha-mannosidosis
    it is internalised by the cells and reaches the lysosomes by mannose-6-phosphate receptor mediated uptake, thus replacing the missing endogenous enzyme...
    14 KB (1,591 words) - 22:28, 27 August 2024
  • administration, it binds mannose-6-phosphate receptors on the cell surface to trigger vesicle formation around the receptor-proenzyme complex. The more...
    19 KB (1,800 words) - 07:30, 15 July 2024
  • bis-mannose-6-phosphate (bis-M6P) tetra-mannose glycans. The bis-MGP of avalglucosidase alpha binds to the cation-independent mannose-6-phosphate receptor...
    16 KB (1,224 words) - 05:11, 16 July 2024
  • Thumbnail for Glucose-6-phosphate isomerase
    with Lys518. When going from fructose-6-phosphate toward glucose-6-phosphate, the result could be mannose-6-phosphate if carbon C2 is given the wrong chirality...
    27 KB (3,057 words) - 12:53, 9 September 2024
  • | Cysteine. Retrieved 2018-10-20. "Molecular cooperation in mannose 6-phosphate receptor transport in SearchWorks catalog". searchworks.stanford.edu....
    6 KB (308 words) - 14:22, 7 August 2024
  • (March 1988). "Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors". The Journal of Biological Chemistry. 263 (7): 3521–7. doi:10...
    33 KB (3,229 words) - 19:54, 7 July 2024