mannose 6-phosphate receptors (MPRs) are transmembrane glycoproteins that target enzymes to lysosomes in vertebrates. Mannose 6-phosphate receptors bind...
26 KB (2,963 words) - 06:28, 30 January 2022
Mannose-6-phosphate (M6P) is a molecule bound by lectin in the immune system. M6P is converted to fructose 6-phosphate by mannose phosphate isomerase...
4 KB (320 words) - 00:19, 4 August 2023
biology, the cation-dependent mannose-6-phosphate receptor (CD-MPR) also known as the 46 kDa mannose 6-phosphate receptor is a protein that in humans is...
10 KB (1,330 words) - 17:41, 16 April 2024
Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
13 KB (1,664 words) - 16:27, 25 May 2024
the EGF receptor have a pH-resistant bond that persists until it is delivered to lysosomes for their degradation. The mannose 6-phosphate receptor carries...
22 KB (2,647 words) - 07:14, 29 May 2024
hexose-6-phosphate.[citation needed] α-Mannosidase Mannose receptor Mannan oligosaccharide-based nutritional supplements Rhamnose, 6-deoxy-L-mannose PTS...
17 KB (1,727 words) - 02:40, 16 September 2024
Mannose-6-phosphate receptor binding protein 1 (M6PRBP1) is a protein which in humans is encoded by the M6PRBP1 gene. Its gene product, as well as the...
11 KB (1,309 words) - 00:27, 24 December 2023
lysosomal membrane proteins and active lysosomal hydrolases, but no mannose-6-phosphate receptor. They are generally regarded as the principal hydrolytic compartment...
25 KB (2,980 words) - 14:58, 19 June 2024
cation-independent mannose-6-phosphate receptor; mannose receptor of macrophages; 180 Kd secretory phospholipase A2 receptor; DEC-205 receptor; 72 Kd and 92...
7 KB (808 words) - 13:40, 22 March 2023
mannose-6-phosphate is accomplished by two proteins: CI-MPR (cation-independent mannose-6-phosphate receptor) and CD-MPR (cation-dependent mannose-6-phosphate...
26 KB (3,161 words) - 19:09, 8 June 2024
from Latin morbilli (measles), parotitis (mumps) and rubella Mannose 6-phosphate receptor, a family of transmembrane proteins that help transport proteins...
2 KB (311 words) - 06:50, 17 August 2024
may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and...
8 KB (990 words) - 17:07, 29 May 2024
death receptors, and chemotherapy drugs. The main mechanism of trafficking L-SMase to the lysosome is through the mannose 6-phosphate receptor mediated...
8 KB (878 words) - 23:29, 13 August 2024
lysosomal tag, mannose 6-phosphate, is added to the peptides. The presence of these tags allow for binding to mannose 6-phosphate receptors in the Golgi...
43 KB (4,709 words) - 14:32, 4 September 2024
an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal...
11 KB (1,389 words) - 20:42, 23 December 2023
p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor (MPR) from endosomes to the trans-Golgi network. RABEPK has been...
4 KB (503 words) - 02:29, 28 March 2022
an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal...
9 KB (1,147 words) - 00:25, 23 December 2023
mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose...
6 KB (701 words) - 16:46, 28 October 2022
has been implicated in endosome to Golgi trafficking of the mannose 6-phosphate receptor and glucose transporter type 4. STX10 has been detected in the...
4 KB (538 words) - 11:19, 11 December 2023
the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor". The Journal of Cell Biology. 165 (1): 123–133. doi:10.1083/jcb...
19 KB (1,993 words) - 06:11, 27 May 2024
like: Spectrum of Genetic Disorders in Arabs, Lebanese type of mannose 6--phosphate receptor recognition defect (1984), Algerian type of spondylometaphyseal...
66 KB (6,343 words) - 13:48, 26 September 2024
Hirokawa N (November 2000). "A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex"...
9 KB (1,138 words) - 00:14, 5 October 2022
S, Edmunds T, Saftig P (November 2007). "LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase". Cell...
18 KB (2,001 words) - 01:59, 27 January 2024
it is internalised by the cells and reaches the lysosomes by mannose-6-phosphate receptor mediated uptake, thus replacing the missing endogenous enzyme...
14 KB (1,591 words) - 22:28, 27 August 2024
administration, it binds mannose-6-phosphate receptors on the cell surface to trigger vesicle formation around the receptor-proenzyme complex. The more...
19 KB (1,800 words) - 07:30, 15 July 2024
bis-mannose-6-phosphate (bis-M6P) tetra-mannose glycans. The bis-MGP of avalglucosidase alpha binds to the cation-independent mannose-6-phosphate receptor...
16 KB (1,224 words) - 05:11, 16 July 2024
with Lys518. When going from fructose-6-phosphate toward glucose-6-phosphate, the result could be mannose-6-phosphate if carbon C2 is given the wrong chirality...
27 KB (3,057 words) - 12:53, 9 September 2024
| Cysteine. Retrieved 2018-10-20. "Molecular cooperation in mannose 6-phosphate receptor transport in SearchWorks catalog". searchworks.stanford.edu....
6 KB (308 words) - 14:22, 7 August 2024
(March 1988). "Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors". The Journal of Biological Chemistry. 263 (7): 3521–7. doi:10...
33 KB (3,229 words) - 19:54, 7 July 2024