Methylmalonic acid (MMA) is a chemical compound from the group of dicarboxylic acids. It consists of the basic structure of malonic acid and also carries...
13 KB (1,206 words) - 17:01, 16 August 2024
buildup of a toxic level of methylmalonic acid in body liquids and tissues. Due to the disturbed branched-chain amino acids (BCAA) metabolism, they are...
49 KB (4,433 words) - 18:08, 16 June 2024
elevated levels of malonic acid and methylmalonic acid. However, the methylmalonic acid levels exceed those of malonic acid. CMAMMA is not only an organic...
32 KB (3,294 words) - 15:59, 4 August 2024
Methylmalonic acid semialdehyde is an intermediate in the metabolism of thymine and valine. Methylmalonate-semialdehyde dehydrogenase (acylating) Voet...
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to methylmalonic acid. It is an important intermediate in the biosynthesis of succinyl-CoA, which plays an essential role in the tricarboxylic acid cycle...
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Vitamin B12 and folate deficiencies. The level of methylmalonic acid is not elevated in folic acid deficiency. Direct measurement of blood cobalamin remains...
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straightforward as serum levels can be falsely high or normal. Elevated methylmalonic acid levels may also indicate a deficiency. Individuals with low or marginal...
118 KB (13,134 words) - 19:21, 1 August 2024
Folate (redirect from Folic Acid)
between folate deficiency and vitamin B12 deficiency is by testing for methylmalonic acid (MMA) levels. Normal MMA levels indicate folate deficiency and elevated...
101 KB (11,049 words) - 02:09, 19 August 2024
metabolic disease combined malonic and methylmalonic aciduria (CMAMMA). By calculating the malonic acid to methylmalonic acid ratio in blood plasma, CMAMMA can...
20 KB (1,956 words) - 16:44, 12 August 2024
decreased methylmalonic acid, increased folate and a decrease in homocysteine. Formiminotransferase cyclodeaminase Glutamate-1-semialdehyde Glutamic acid...
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Folate deficiency (redirect from Folic acid deficiency)
homocysteine to methionine) as in vitamin B12 deficiency, whereas methylmalonic acid is normal (elevated in vitamin B12 deficiency).[citation needed] More...
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Carboxylic acids are organic acids characterized by a carboxyl (-COOH) functional group. The naming of these compounds is governed by IUPAC nomenclature...
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deficiency. In addition, elevated methylmalonic acid levels may also be related to metabolic disorders such as methylmalonic acidemia. If nervous system damage...
112 KB (12,247 words) - 15:40, 25 August 2024
advancement, a jaw surgical procedure Methylmalonic acidemia, an autosomal genetic disorder Methylmalonic acid Middle meningeal artery Monomelic amyotrophy...
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Malonic aciduria (category Fatty-acid metabolism disorders)
malonic acid to methylmalonic acid ratio in blood plasma, malonic aciduria can be clearly distinguished from combined malonic and methylmalonic aciduria...
15 KB (1,717 words) - 19:44, 16 May 2024
higher levels of methylmalonic acid than malonic acid, although both are elevated. By calculating the malonic acid to methylmalonic acid ratio in blood...
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not capable of utilizing lipoic acid as a sulfur source. In the metabolic disease combined malonic and methylmalonic aciduria (CMAMMA) due to ACSF3 deficiency...
48 KB (4,958 words) - 01:02, 6 August 2024
Valine (redirect from Α-Aminoisovaleric acid)
metabolic diseases: Combined malonic and methylmalonic aciduria (CMAMMA) Maple syrup urine disease (MSUD) Methylmalonic acidemia Propionic acidemia Lower levels...
14 KB (1,152 words) - 11:04, 19 February 2024
vitamin B12, methylmalonic acid, Schilling test, and a complete blood count, looking for megaloblastic anemia if there is also folic acid deficiency or...
9 KB (912 words) - 22:28, 24 February 2024
2-ethyl-2-methylmalonic acid reported in 1904. A slight excess of the levorotary form of the product of the reaction, 2-methylbutyric acid, was produced;...
41 KB (4,726 words) - 05:21, 27 May 2024
mitochondria fails due to Vitamin B 12 deficiency, elevated blood levels of methylmalonic acid (MMA) occur. Thus, elevated blood levels of homocysteine and MMA may...
30 KB (2,655 words) - 03:29, 5 August 2024
"Nutritional Supplementation with Chlorella pyrenoidosa Lowers Serum Methylmalonic Acid in Vegans and Vegetarians with a Suspected Vitamin B₁₂ Deficiency"...
22 KB (2,527 words) - 01:57, 19 August 2024
Homocysteine (category Alpha-Amino acids)
where it is accompanied by decreased methylmalonic acid, increased folate, and a decrease in formiminoglutamic acid. This is the opposite of MTHFR C677T...
24 KB (1,987 words) - 17:48, 14 August 2024
reactions: the mitochondrial methylmalonyl-CoA mutase conversion of methylmalonic acid (MMA) to succinate, which links lipid and carbohydrate metabolism...
21 KB (2,021 words) - 18:44, 15 July 2024
Alkaptonuria Aspartylglucosaminuria Branched-chain keto acid dehydrogenase kinase deficiency Methylmalonic acidemia Maple syrup urine disease Homocystinuria...
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are more commonly recognized by name than by number, such as pantothenic acid (B5), biotin (B7), and folate (B9). B vitamins are present in protein-rich...
43 KB (2,802 words) - 13:39, 23 August 2024
deficiency due to its role in metabolic processes and cellular functions. Methylmalonic acid (MMA) can be measured in both the blood and urine, whereas homocysteine...
56 KB (6,027 words) - 12:46, 25 April 2024
serum levels of Vitamin B12, methylmalonic acid, and homocysteine. If there is no clear evidence of Vitamin B12 or folic acid deficiency, additional causes...
9 KB (974 words) - 20:30, 30 May 2024
biochemistry, fatty acid synthesis is the creation of fatty acids from acetyl-CoA and NADPH through the action of enzymes called fatty acid synthases. This...
41 KB (4,751 words) - 16:31, 17 August 2024
types of methylmalonic aciduria. MCM was first identified in rat liver and sheep kidney in 1955. In its latent form, it is 750 amino acids in length...
25 KB (2,921 words) - 14:57, 26 August 2023