Myosin light-chain kinase also known as MYLK or MLCK is a serine/threonine-specific protein kinase that phosphorylates a specific myosin light chain, namely...
16 KB (1,731 words) - 22:49, 9 January 2024
A myosin light chain is a light chain (small polypeptide subunit) of myosin. Myosin light chains were discovered by Chinese biochemist Cao Tianqin (Tien-chin...
8 KB (1,021 words) - 21:26, 18 May 2023
kinase C and Rho-associated protein kinase are involved in regulating calcium ion intake; these calcium ions, in turn stimulate a myosin light chain kinase...
19 KB (2,170 words) - 06:41, 27 May 2024
Myosin light-chain phosphatase, also called myosin phosphatase (EC 3.1.3.53; systematic name [myosin-light-chain]-phosphate phosphohydrolase), is an enzyme...
14 KB (1,600 words) - 15:01, 26 August 2023
Smooth muscle (section Myosin)
calcium sensitization. The myosin light chain phosphatase is inhibited to increase the gain or sensitivity of myosin light chain kinase to calcium. There are...
37 KB (4,738 words) - 20:27, 18 July 2024
Myosin light chain kinase, smooth muscle also known as kinase-related protein (KRP) or telokin is an enzyme that in humans is encoded by the MYLK gene...
5 KB (726 words) - 01:59, 1 December 2023
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) also known as the regulatory light chain of myosin (RLC) is a protein that...
32 KB (3,867 words) - 09:33, 24 December 2023
levels. Protein kinase Signal transduction G protein-coupled receptor Serine/threonine-specific protein kinase Myosin light-chain kinase cAMP-dependent...
27 KB (2,665 words) - 17:03, 6 April 2024
In enzymology, a myosin-heavy-chain kinase (EC 2.7.11.7) is an enzyme that catalyzes the chemical reaction ATP + [myosin heavy-chain] ⇌ {\displaystyle...
5 KB (546 words) - 15:01, 26 August 2023
Myosin light chain kinase 2 also known as MYLK2 is an enzyme which in humans is encoded by the MYLK2 gene. This gene encodes a myosin light chain kinase...
6 KB (777 words) - 02:00, 1 December 2023
Myosin light chain kinase 3 also known as MYLK3, is an enzyme which in humans is encoded by the MYLK3 gene. Phosphorylation of cardiac myosin heavy chains...
5 KB (666 words) - 16:50, 28 October 2022
kinase is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), ultraviolet light,...
14 KB (1,385 words) - 10:32, 28 April 2024
biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that...
11 KB (1,128 words) - 19:03, 18 September 2023
Atrial Light Chain-2 (ALC-2) also known as Myosin regulatory light chain 2, atrial isoform (MLC2a) is a protein that in humans is encoded by the MYL7...
19 KB (2,346 words) - 10:57, 16 January 2024
There are two types of CaM kinase: Specialized CaM kinases, such as the myosin light chain kinase that phosphorylates myosin, causing smooth muscles to...
29 KB (3,458 words) - 16:39, 17 March 2024
CAMK (redirect from Calcium/calmodulin-dependent protein kinase II)
myosin light chain kinases. This group of proteins includes CAMK III. More on CAMKIII can be found following this link. Multi-functional CAM Kinases have...
8 KB (886 words) - 12:46, 31 January 2024
Wortmannin (category Phosphoinositide 3-kinase inhibitors)
DNA-PKcs, some phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK) at high concentrations Wortmannin...
12 KB (1,138 words) - 05:28, 7 May 2024
5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
65 KB (7,147 words) - 05:41, 24 June 2024
preferentially expressed protein kinase, in the human is encoded by the SPEG gene, a member of the myosin light chain kinase protein family. SPEG is involved...
8 KB (832 words) - 22:28, 2 December 2023
c-Jun N-terminal kinases (JNKs), were originally identified as kinases that bind and phosphorylate c-Jun on Ser-63 and Ser-73 within its transcriptional...
14 KB (1,626 words) - 20:50, 30 May 2024
known as kinase-related protein or KRP) is an abundant protein found in smooth-muscle. It is identical to the C-terminus of myosin light-chain kinase. Telokin...
20 KB (2,505 words) - 01:35, 15 October 2022
side chains. At least 350 of the 500+ human protein kinases are serine/threonine kinases (STK). In enzymology, the term serine/threonine protein kinase describes...
14 KB (1,210 words) - 13:35, 14 June 2024
Myosin light chain kinase 4 also known as MYLK4 is an enzyme which in humans is encoded by the MYLK2 gene. MYLK4 is a member of the myosin light-chain...
4 KB (330 words) - 09:34, 10 March 2024
MYL9 (redirect from 20 kd myosin light chain)
modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding...
4 KB (523 words) - 20:54, 21 December 2023
activates myosin light-chain kinase. The calcium-calmodulin-myosin light-chain kinase complex phosphorylates myosin on the 20 kilodalton (kDa) myosin light chains...
62 KB (7,395 words) - 16:30, 12 July 2024
cells and activates protein kinase A. Both of these changes inactivate myosin light-chain kinase and activate myosin light-chain phosphatase. In addition...
18 KB (1,703 words) - 06:18, 17 March 2024
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
35 KB (3,829 words) - 14:24, 17 June 2024
protein (GFP), calmodulin (CaM), and M13, a peptide sequence from myosin light-chain kinase. When bound to Ca2+, GCaMP fluoresces green with a peak excitation...
28 KB (3,065 words) - 01:46, 30 March 2024
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
46 KB (5,492 words) - 03:05, 21 June 2024
Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
35 KB (3,831 words) - 00:20, 19 July 2024