enzyme phenylalanine ammonia lyase (EC 4.3.1.24) catalyzes the conversion of L-phenylalanine to ammonia and trans-cinnamic acid.: L-phenylalanine = trans-cinnamate...
20 KB (2,185 words) - 06:53, 3 November 2024
Phenylalanine/tyrosine ammonia-lyase (EC 4.3.1.25, PTAL, bifunctional PAL) is an enzyme with systematic name L-phenylalanine(or L-tyrosine):trans-cinnamate(or...
3 KB (285 words) - 12:08, 29 November 2023
histidase are associated with histidinemia and urocanic aciduria. Phenylalanine ammonia-lyase, another enzyme that contains the MIO cofactor GRCh38: Ensembl...
5 KB (638 words) - 11:14, 18 May 2024
Phenylalanine is converted to cinnamic acid by the enzyme phenylalanine ammonia-lyase. Phenylalanine is biosynthesized via the shikimate pathway. The genetic...
28 KB (2,386 words) - 21:26, 25 July 2024
pathway, in which the natural amino acid L-phenylalanine undergoes a deamination by phenylalanine ammonia lyase to afford (E)-cinnamate. The resulting monocarboxylate...
15 KB (1,228 words) - 16:46, 20 September 2024
3,4-dihydroxyphenylalanine reductive deaminase (redirect from 3,4-dihydroxy-L-phenylalanine ammonia-lyase (3,4-dihydroxyphenylpropanoate-forming))
DOPA-reductive deaminase, DOPARDA; systematic name 3,4-dihydroxy-L-phenylalanine ammonia-lyase (3,4-dihydroxyphenylpropanoate-forming)) catalyses the following...
1 KB (116 words) - 04:16, 28 November 2023
Phenylketonuria (redirect from Deficiency disease, Phenylalanine Hydroxylase)
clinical trials to investigate PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase or 'PAL'), which is an enzyme substitution therapy in which the...
57 KB (6,179 words) - 14:29, 25 October 2024
biosynthesized from phenylalanine. Deamination of L-phenylalanine into cinnamic acid is catalyzed by phenylalanine ammonia lyase (PAL). PAL catalyzes...
20 KB (1,852 words) - 14:49, 9 September 2024
and scent compounds. Phenylalanine is first converted to cinnamic acid by the action of the enzyme phenylalanine ammonia-lyase (PAL). Some plants, mainly...
6 KB (619 words) - 17:20, 7 October 2024
phenylketonuria. It is a phenylalanine (Phe)‑metabolizing enzyme. Chemically, it is a pegylated derivative of the enzyme phenylalanine ammonia-lyase that metabolizes...
8 KB (531 words) - 03:53, 22 May 2024
important electrophilic catalytic residue in histidine ammonia-lyase and phenylalanine ammonia-lyase enzymes, but the active residue was later found instead...
8 KB (706 words) - 04:26, 3 February 2024
Ammonia + H+ L-tyrosine = trans-p-hydroxycinnamate + NH3 EC 4.3.1.24 (phenylalanine ammonia-lyase) EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase)...
2 KB (212 words) - 21:37, 18 August 2023
the phenylpropanoid pathway starting with L-phenylalanine, which is deaminated by phenylalanine ammonia lyase (PAL) to form t-cinnamic acid. The para position...
37 KB (3,760 words) - 19:49, 24 November 2024
Threonine ammonia-lyase (EC 4.3.1.19, systematic name L-threonine ammonia-lyase (2-oxobutanoate-forming), also commonly referred to as threonine deaminase...
15 KB (1,683 words) - 16:02, 26 August 2023
Its biosynthesis involves the action of the enzyme phenylalanine ammonia-lyase (PAL) on phenylalanine. It is obtained from oil of cinnamon, or from balsams...
9 KB (686 words) - 16:52, 23 October 2024
Permissive action link, a security device for nuclear weapons Phenylalanine ammonia-lyase, a class of enzymes PAL Airlines, Canada PAL Airlines (Chile)...
4 KB (467 words) - 13:25, 8 August 2024
studies identified phenylalanine and valine as the precursors to capsaicin. Enzymes of the phenylpropanoid pathway, phenylalanine ammonia lyase (PAL), cinnamate...
59 KB (5,930 words) - 11:59, 20 November 2024
phenylalanine is converted to 4-coumaroyl-CoA in a series of steps known as the general phenylpropanoid pathway using phenylalanine ammonia-lyase,...
26 KB (2,467 words) - 13:46, 2 November 2024
DMG-PEG 2000. Pegvaliase (Biomarin) – PEGylated recombinant phenylalanine ammonia-lyase for the treatment of Phenylketonuria, approved by the FDA for...
27 KB (2,986 words) - 00:38, 24 October 2024
indicated in blue, abbreviated as follows: E1, phenylalanine ammonia lyase (PAL), E2, tyrosine ammonia lyase (TAL), E3, cinnamate 4-hydroxylase, E4, 4-coumaroyl:...
19 KB (1,905 words) - 20:10, 13 May 2024
first enzyme involved is phenylalanine ammonia-lyase (PAL) that converts L-phenylalanine to trans-cinnamic acid and ammonia. Gallic acid is formed from...
12 KB (1,163 words) - 14:21, 2 October 2024
List of EC numbers (EC 4) (redirect from Phosphorus-oxygen lyases)
(tyrosine ammonia-lyase), EC 4.3.1.24 (phenylalanine ammonia-lyase) and EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase) EC 4.3.1.6: β-alanyl-CoA ammonia-lyase...
62 KB (7,931 words) - 19:04, 4 January 2024
coat. Starting with the transformation of phenylalanine into cinnamic acid mediated by phenylalanine ammonia-lyase. Cinnamic acid will then go through two...
21 KB (2,233 words) - 08:08, 21 August 2024
L-phenylalanine, first the amino acid is non-oxidatively deaminated by phenylalanine ammonia lyase (PAL) to make cinnamate, followed by oxidation at the para position...
12 KB (1,048 words) - 22:47, 25 October 2024
khat begins with L-phenylalanine and the first step is carried out by L-phenylalanine ammonia lyase (PAL), which cleaves off an ammonia group and creates...
27 KB (2,633 words) - 14:32, 6 November 2024
new pathway proposed suggests that phenylalanine first forms cinnamoyl-CoA via the enzymes phenylalanine ammonia-lyase and acyl CoA ligase. The cinnamoyl-CoA...
66 KB (6,171 words) - 19:40, 17 November 2024
20) Category:EC 4.3.1 Phenylalanine ammonia-lyase (EC 4.3.1.24) Category:EC 4.4.1 Cystathionine gamma-lyase Cystathionine beta-lyase Leukotriene C4 synthase...
33 KB (3,650 words) - 18:48, 10 September 2024
cones. L-Phenylalanine serves as the starting material, which is converted to cinnamic acid by the PLP-dependent phenylalanine ammonia lyase. Cinnamic...
9 KB (833 words) - 10:44, 16 June 2024
alba L.) leaves begins with phenylalanine, which produces cinnamic acid under the action of phenylalanine ammonia lyase (PAL). Cinnamic acid is catalyzed...
13 KB (1,077 words) - 23:11, 12 September 2024
2017, Codexis developed a recombinant phenylalanine ammonia-lyase (PAL) enzyme, to act as a substitute phenylalanine hydroxylase (PAH) enzyme for people...
7 KB (472 words) - 08:14, 19 October 2024