• Thumbnail for Plexin
    A plexin is a protein which acts as a receptor for semaphorin family signaling proteins. It is classically known for its expression on the surface of axon...
    15 KB (1,611 words) - 18:10, 23 May 2024
  • Thumbnail for Plexin A1
    Plexin-A1 is a protein that in humans is encoded by the PLXNA1 gene. Plexin A1 has been shown to interact with AKT1. GRCh38: Ensembl release 89: ENSG00000114554...
    6 KB (703 words) - 22:19, 3 March 2023
  • Thumbnail for PLXNB1
    PLXNB1 (redirect from Plexin B1)
    Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene. Within neural tissues, the plexin family serves as transmembrane...
    10 KB (1,248 words) - 07:34, 24 December 2023
  • Thumbnail for Optic chiasm
    (Sema6D) expressed at the midline, which form a complex that signals to Nr-CAM/Plexin-A1 receptors on crossing RGC axons. Since all vertebrates, even the earliest...
    15 KB (1,712 words) - 17:03, 3 July 2024
  • Thumbnail for PLXNA4A
    Plexin-A4 is a protein that in humans is encoded by the PLXNA4 gene. Plexin A4 binds to neuropilin 1 (Nrp1) and neuropilin 2 (Nrp2) and transduces signals...
    6 KB (723 words) - 23:59, 3 March 2023
  • Thumbnail for Synaptic pruning
    in mice that have a Plexin-A3 defect. Specifically, axons that are connected to a transient target will retract once the Plexin-A3 receptors are activated...
    23 KB (2,972 words) - 02:10, 7 June 2024
  • Thumbnail for SEMA4D
    induces growth cone collapse in the central nervous system. By binding plexin B1 receptor it functions as an R-Ras GTPase-activating protein (GAP) and...
    10 KB (1,298 words) - 12:06, 29 December 2024
  • Thumbnail for Dendrite
    tyrosine kinase receptors, BMP7, Wnt/dishevelled, EPHB 1–3, Semaphorin/plexin-neuropilin, slit-robo, netrin-frazzled, reelin. Rac, CDC42 and RhoA serve...
    25 KB (2,885 words) - 02:45, 6 November 2024
  • Thumbnail for PLXNB3
    Plexin-B3 is a protein that in humans is encoded by the PLXNB3 gene. PLXNB3 has been shown to interact with ARHGEF11. GRCh38: Ensembl release 89: ENSG00000198753...
    5 KB (657 words) - 20:03, 3 December 2023
  • Thumbnail for PLXDC2
    Plexin domain-containing protein 2 is a protein that in humans is encoded by the PLXDC2 gene. GRCh38: Ensembl release 89: ENSG00000120594 – Ensembl, May...
    3 KB (382 words) - 12:33, 16 January 2024
  • Thumbnail for Semaphorin-3A
    Nakamura F, Wang LH, Murakami Y, Kalb RG, Fujisawa H, Strittmatter SM (1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99...
    14 KB (1,729 words) - 23:05, 27 March 2024
  • Thumbnail for PLXDC1
    Plexin domain-containing protein 1 is a protein that in humans is encoded by the PLXDC1 gene. Plexin PLXDC2 Protein domain GRCh38: Ensembl release 89:...
    3 KB (425 words) - 17:12, 21 September 2024
  • Thumbnail for Sema domain
    also occur in the hepatocyte growth factor receptor (Uniprot: P08581), Plexin-A3 (Uniprot: P51805) and in viral proteins. CD100 (also called SEMA4D) is...
    4 KB (520 words) - 19:02, 6 July 2021
  • the association of L1CAM with neuropilin-1. Neuropilin-1 interacts with Plexin-A proteins to form the Semaphorin-3A receptor complex. Semaphorin-a3A is...
    36 KB (3,347 words) - 19:00, 17 April 2024
  • Thumbnail for PLXND1
    Plexin-D1 is a protein that in humans is encoded by the PLXND1 gene. GRCh38: Ensembl release 89: ENSG00000004399 – Ensembl, May 2017 GRCm38: Ensembl release...
    4 KB (453 words) - 23:20, 20 February 2024
  • Thumbnail for PLXNA3
    Plexin-A3 is a protein that in humans is encoded by the PLXNA3 gene. GRCh38: Ensembl release 89: ENSG00000130827 – Ensembl, May 2017 GRCm38: Ensembl release...
    4 KB (581 words) - 23:07, 4 September 2022
  • Thumbnail for PLXNA2
    Plexin-A2 is a protein that in humans is coded by the PLXNA2 gene. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins...
    6 KB (773 words) - 06:38, 3 June 2024
  • Thumbnail for SEMA3F
    PMID 15520858. Gu C, Yoshida Y, Livet J, et al. (2005). "Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins". Science. 307...
    8 KB (1,081 words) - 16:27, 27 November 2023
  • Thumbnail for Tropic cues involved in growth cone guidance
    H (Mar 2003). "Identification and characterization of a novel mouse plexin, plexin-A4". Mechanisms of Development. 120 (3): 385–96. doi:10.1016/S0925-4773(02)00421-5...
    26 KB (3,128 words) - 20:51, 23 September 2024
  • Thumbnail for Chromosome 17
    protein ORMDL sphingolipid biosynthesis regulator 3 PLXDC1: encoding protein Plexin domain-containing protein 1 PNPO: encoding enzyme Pyridoxine-5'-phosphate...
    29 KB (2,205 words) - 03:14, 5 January 2025
  • as Huntington's chorea, fragile X syndrome and myotonic dystrophy. CD232 Plexin-C1 (PLXNC1 gene); also called Virus-encoded semaphorin protein receptor...
    96 KB (492 words) - 06:06, 25 November 2024
  • Thumbnail for Semaphorin 3E
    proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based...
    4 KB (618 words) - 07:59, 3 December 2023
  • Thumbnail for ARHGEF11
    (Jul 2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"...
    13 KB (1,581 words) - 19:22, 27 July 2024
  • Thumbnail for Neuropilin 1
    Fournier A, Nakamura F, Wang LH, Murakami Y, Kalb RG, et al. (October 1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99...
    16 KB (1,812 words) - 06:08, 27 September 2024
  • Thumbnail for PLXNB2
    Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene. Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that...
    6 KB (739 words) - 11:43, 4 March 2023
  • Thumbnail for Neuropilin
    documented to regulate neurogenesis and angiogenesis by complexing with Plexin receptors/class-3 semaphorin ligands and Vascular Endothelial Growth Factor...
    11 KB (1,055 words) - 03:34, 23 June 2024
  • Thumbnail for Retinal ganglion cell
    RGCs and the midline glia and acts along with Sema6D, mediated via the plexin-A1 receptor. VEGF-A is released from the midline directs RGCs to take a...
    30 KB (3,656 words) - 16:52, 22 October 2024
  • Thumbnail for Glial cell line-derived neurotrophic factor
    embryonic organ development chemoattraction of axon commissural neuron axon guidance regulation of semaphorin-plexin signaling pathway Sources:Amigo / QuickGO...
    25 KB (2,883 words) - 06:11, 13 September 2024
  • Thumbnail for Rnd1
    (Jul 2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"...
    8 KB (955 words) - 17:20, 11 April 2024
  • Thumbnail for VEGF receptor
    Blondelle J, Singh MK, Flaherty KM, Means PC, et al. (August 2011). "Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1"...
    8 KB (754 words) - 13:03, 18 September 2024