• Thumbnail for Protease
    A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides...
    26 KB (2,799 words) - 15:02, 30 June 2024
  • Thumbnail for Serine protease
    Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins. Serine serves as the nucleophilic amino acid at the (enzyme's)...
    22 KB (2,343 words) - 20:13, 29 August 2024
  • Protease inhibitor can refer to: Protease inhibitor (pharmacology): a class of medication that inhibits viral protease Protease inhibitor (biology): molecules...
    250 bytes (55 words) - 20:49, 9 June 2020
  • and COVID-19. These protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease) and blocking proteolytic...
    12 KB (838 words) - 10:11, 12 August 2024
  • Thumbnail for Catalytic triad
    triads are most commonly found in hydrolase and transferase enzymes (e.g. proteases, amidases, esterases, acylases, lipases and β-lactamases). An acid-base-nucleophile...
    57 KB (5,790 words) - 20:33, 13 May 2024
  • Protease A may refer to one of two enzymes: Streptogrisin A Omptin This disambiguation page lists articles associated with the title Protease A. If an...
    95 bytes (44 words) - 19:59, 29 December 2019
  • Thumbnail for Cysteine protease
    Cysteine proteases, also known as thiol proteases, are hydrolase enzymes that degrade proteins. These proteases share a common catalytic mechanism that...
    14 KB (1,278 words) - 22:29, 25 April 2024
  • Thumbnail for TEV protease
    three proteases: P1 protease (1 cleavage site), helper-component protease (1 cleavage site) and TEV protease (7 cleavage sites). The native TEV protease also...
    16 KB (1,866 words) - 02:28, 14 August 2024
  • two classes of acidic proteases: Aspartic proteases - that use a catalytic aspartic acid in their active site Glutamic proteases - that use a catalytic...
    244 bytes (65 words) - 21:07, 9 March 2016
  • Thumbnail for 3C-like protease
    3C-like protease (3CLpro) or main protease (Mpro), formally known as C30 endopeptidase or 3-chymotrypsin-like protease, is the main protease found in...
    17 KB (1,653 words) - 12:43, 26 September 2024
  • Thumbnail for Prion
    Prion (redirect from Protease-resistant PrP)
    found in infectious prions has a different structure and is resistant to proteases, the enzymes in the body that can normally break down proteins. The normal...
    99 KB (10,732 words) - 13:28, 2 November 2024
  • Thumbnail for Lon protease family
    In molecular biology, the Lon protease family is a family of enzymes that break peptide bonds in proteins resulting in smaller peptides or amino acids...
    4 KB (397 words) - 12:40, 9 July 2023
  • Flavivirin (EC 3.4.21.91, Yellow fever virus (flavivirus) protease, NS2B-3 proteinase) is a protease, a type of enzyme. Chambers TJ, Hahn CS, Galler R, Rice...
    2 KB (186 words) - 02:47, 27 September 2024
  • Protease-activated receptors (PAR) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular...
    12 KB (1,250 words) - 19:00, 13 March 2024
  • Thumbnail for Rhomboid protease
    The rhomboid proteases are a family of enzymes that exist in almost all species. They are proteases: they cut the polypeptide chain of other proteins....
    42 KB (4,629 words) - 01:58, 16 December 2023
  • Thumbnail for Proteinase K
    Proteinase K (redirect from Protease K)
    In molecular biology, Proteinase K (EC 3.4.21.64, protease K, endopeptidase K, Tritirachium alkaline proteinase, Tritirachium album serine proteinase,...
    10 KB (1,063 words) - 20:45, 11 September 2024
  • Thumbnail for Threonine protease
    Threonine proteases are a family of proteolytic enzymes harbouring a threonine (Thr) residue within the active site. The prototype members of this class...
    5 KB (434 words) - 22:58, 25 April 2024
  • Thumbnail for Degradomics
    study of proteases, their inhibitors, and their substrates on a system-wide scale. This includes the analysis of the protease and protease-substrate...
    36 KB (5,012 words) - 20:38, 12 July 2024
  • Thumbnail for Variably protease-sensitive prionopathy
    Variably protease-sensitive prionopathy (VPSPr) (formerly known as Protease Sensitive Prionopathy) is a sporadic prion protein disease first described...
    9 KB (910 words) - 13:01, 24 January 2024
  • Thumbnail for HIV-1 protease
    HIV-1 protease or PR is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential...
    20 KB (2,197 words) - 00:57, 13 January 2024
  • Thumbnail for Pancreatic enzymes (medication)
    pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, protease and lactase. They are used to treat malabsorption syndrome due to certain...
    17 KB (1,422 words) - 23:27, 1 November 2024
  • Proteases (also sometimes referred to as proteolytic enzymes or peptidases) are in use, or have been proposed or tried, for a number of purposes related...
    12 KB (1,339 words) - 16:56, 29 June 2023
  • Thumbnail for Serpin
    proteins with similar structures that were first identified for their protease inhibition activity and are found in all kingdoms of life. The acronym...
    137 KB (14,301 words) - 14:45, 2 November 2024
  • Thumbnail for Actinidain
    22.14, actinidin, Actinidia anionic protease, proteinase A2 of Actinidia chinensis) is a type of cysteine protease enzyme found in fruits including kiwifruit...
    16 KB (1,922 words) - 08:00, 1 September 2024
  • picornavirus endopeptidase 2A, poliovirus protease 2A, rhinovirus protease 2A, 2A protease, 2A proteinase, protease 2A, proteinase 2Apro, picornaviral 2A...
    2 KB (198 words) - 15:28, 26 August 2023
  • In biology and biochemistry, protease inhibitors, or antiproteases, are molecules that inhibit the function of proteases (enzymes that aid the breakdown...
    20 KB (1,858 words) - 03:56, 20 October 2024
  • Thumbnail for Aspartic protease
    Aspartic proteases (also "aspartyl proteases", "aspartic endopeptidases") are a catalytic type of protease enzymes that use an activated water molecule...
    10 KB (999 words) - 06:14, 23 February 2023
  • (HIV protease inhibitor) Darunavir (HIV protease inhibitor) Delavirdine (non-nucleoside reverse transcriptase inhibitor) Fosamprenavir (HIV protease inhibitor)...
    4 KB (260 words) - 16:19, 11 August 2024
  • Thumbnail for ADAMTS13
    type 1 motif, member 13)—also known as von Willebrand factor-cleaving protease (VWFCP)—is a zinc-containing metalloprotease enzyme that cleaves von Willebrand...
    12 KB (1,420 words) - 09:40, 14 January 2024
  • Thumbnail for Active site
    produce a favourable interaction. Many enzymes including serine protease, cysteine protease, protein kinase and phosphatase evolved to form transient covalent...
    41 KB (4,859 words) - 19:37, 18 September 2024